Can CBD Help IVDD in Dogs?
When I was approached to join the CBD Dog Health team, I didn’t hesitate for even a second to say yes. Cannabis had changed my life and when I learned it could help change animal’s lives too, I knew what I was supposed to be doing with my life. Since I’ve joined, CBD has dramatically improved the life of my own beloved dog, Blanche, who suffered terribly from acute separation anxiety, but I have been so grateful to be able to witness countless other pets who could barely walk, start to RUN. Seizures, allergies, all levels of anxiety – GONE!
It’s been an incredible journey, but I have to admit how difficult it can be to hear of so many animals suffering and these poor pet parents who are so scared to try this all natural medicine because of the stigma surrounding it. I’ve spent HOURS on the phone with stressed out pet owners doing my very best to educate and guide them into being comfortable using cannabis medicine. It’s simply a matter of education and understanding. As exhausting as it can be, it is ALWAYS worth it when I get to hear all of the incredible success stories from all over the country. Happy, healthy pets and relieved owners! So now, I want to share some of these stories with you.
One of our favorite stories was with a beautiful dog named Olivia who we helped live out her very best life, pain free for her last year. A few months ago, Olivia’s mother contacted us to let us know that her sweet girl had passed away peacefully. It was so sad to hear. I took a breath and told her that because she decided to share Olivia’s story to our audience, she’s been able to help hundreds of other dogs live healthy, happy, pain free lives. Her story has helped other pet parents understand the benefits of using CBD for their pet’s health needs. Because sometimes, all you have to do is see it for yourself and that gives you the faith you need to dive in on something like CBD. So Olivia lives on in each of those animal’s lives. She has impacted them through her story and has helped so many other animals who needed a solution. And that’s why we do what we do. My hope in writing these success story blogs is for you to see how much CBD can improve other pet’s lives to help you take the leap of faith and start healing your animals NATURALLY too. Sharing real stories, from real pet owners is the best way for us to demonstrate the true success and effectiveness of CBD. So let’s get this storytime started!
Table of Contents
CBD FOR IVDD
Success Story: Toothless
“This is Toothless! He is a gem and stole our hearts as soon as we met him. We rescued him 4 years ago, but the past he left behind is catching up to him. The little fella suffers from IVDD (disc disease), and sadly he collided with his big k9 sister coming in from outside. It was the worst “flare-up” we have ever seen. We went to the emergency vet twice and after he was fully loaded with SO MANY drugs, it just wasn’t working. He was spending his days whimpering and yelping out in pain.”
“Heads hung, feeling defeated & preparing for the worst, we decided to try alternative and less invasive methods. I found a local vet that thinks more holistically and got our boy in for a consult. We’re now on a path to recovery with acupuncture, laser therapy, and you guessed it – CBD oil! EASE, to be exact!”
“Since his first porcupine sessions and applications of the oil, our boy is finally able to rest and let his body heal. Inflammation is decreasing and his ears are finally standing upright again. There’s no doubt that we are early in this process, or that we have a ways to go, but we are so relieved to have found something that seems to provide relief and isn’t pumping him full of contradicting medicines!”
WHAT IS IVDD?
Intervertebral Disc Disease (IVDD) is a degenerative disease where the cushioning disks between the vertebrate of the spinal column bulge or burst into the spinal cord space. When this happens the disk will press against the nerve that runs on the spinal cord. It is one of the most common neurological issues seen in pets and unfortunately, is something that can come with age and can happen at any time. This can lead to extreme pain, nerve damage, or even paralysis. Depending on the location of the damaged disk, problems can occur anywhere in the body (though in cats it’s mostly found in the neck and upper back).
IVDD is most commonly found in short-legged breeds like dachshunds and beagles and especially in obese and out of shape dogs.
A few ways to tell if your dog is suffering from IVDD:
- Unable to move neck
- Back Pain
- Crying when touched
- Abdominal tenderness
- Dragging their leg(s)
- Falling over
- Reduced Appetite
- Loss of bowel or bladder control
- Arched back
- Unwillingness to jump
HOW CBD CAN HELP YOUR ANIMAL WITH IVDD?
REDUCE PAIN AND INFLAMMATION
What matters most with an animal suffering from IVDD is preserving their quality of life! We want to reduce the pain and inflammation as much as possible. Generally, a veterinarian would recommend or prescribe an NSAID like Rimadyl. Unfortunately, these drugs are tough on our animal’s bodies and can cause things like stomach ulcers, kidney failure, and liver toxicity. CBD is a natural, side effect free solution to help your animal with pain and inflammation.
CBD works with the endocannabinoid system to reduce inflammation. For millions of years, the endocannabinoid system has existed in almost every living organism from humans to animals and even some insects. This universal system’s overall function is to regulate homeostasis within the body.
CBD provides communication between varying types of cells within our bodies using receptors. These communications regulate certain cells to act in defense of the body. For example, if you are injured, CBD helps instruct cells on how to handle the injury.
A Baylor College of Medicine study, using In vitro and in mouse models, found that CBD significantly attenuated the production of proinflammatory cytokines IL-6 and TNF-α while elevating levels of anti-inflammatory IL-10. In the veterinary study, CBD significantly decreased pain and increased mobility in a dose-dependent fashion among animals with an affirmative diagnosis of OA.
Another study published in 2006 in Current Neuropharmacology also states that cannabinoid receptors have shown therapeutic value against inflammatory and neuropathic pains and also concluded that CBD has therapeutic benefits for both people and pets suffering from chronic pain and acute chronic pain episodes.
Did you know that the U.S. government has a patent on cannabis as a neuro-protectant? As a neuro-protectant, CBD helps reduce damage to the brain and nervous system and encourages the growth and development of new neurons. A condition such as IVDD can create permanent neural damage, but studies have shown that CBD is able to protect against this damage and improve recovery.
A recent study suggests that “the endocannabinoids acting through CB1 and CB2 receptors are part of an early neuroprotective response triggered after SCI that is involved in the spontaneous recovery after an incomplete lesion.”
Another study done on mice concluded, “Cannabidiol improved locomotor functional recovery and reduced injury extent, suggesting that it could be useful in the treatment of spinal cord lesions.”
IVDD can be a very scary and traumatic time for your cat or dog. Dealing with chronic pain and possibly losing the ability to walk is very challenging and upsetting for your pet and for you as well. If your animal has had to go through surgery for IVDD, they are confined to a crate to keep them immobile for a few weeks afterward which causes a great deal of stress and anxiety for many pets who may be unaccustomed to being crated. Using CBD to help ease their anxiety is an excellent way to help your animal rest peacefully during their recovery and every day.
PREVENT MUSCLE SPASMS
Muscle spasms are a common side effect of IVDD. Unfortunately, these spasms can be very painful to your animal so it’s really important to control them as much as possible. Full Spectrum CBD can help with these muscle spasms and keep your pet more comfortable.
DOSING CBD for IVDD
It may seem strange, but It’s very important to understand that the dosing of CBD has very little to do with the size or the weight of the animal and more to do with their particular ailment and the animal’s specific needs. For example, a small dog suffering from cancer would need a lot more than a big dog with anxiety. Studies have demonstrated the safety of using CBD, even extremely high doses, so you have nothing to worry about.
Finding the correct dose of CBD for IVDD may take a little bit of trial and error. I recommend keeping a daily journal to document and moderate how much you are giving and what dose is making them feel better. Remember, while CBD isn’t proven to cure the issue, it is all about improving your beloved pet’s QUALITY OF LIFE!
Decide on the starting daily dose (based on our experience, I would start at around 20mg a day) and check-in after a few days. Have you noticed a difference in their mobility and comfort level? Do you think they need more? Are they doing great and you want to see if they could do just as well with a lesser amount? Log these details and you will be able to discern the exact dosage that you need to see the desired results. Each pet is unique and different so get comfortable with making adjustments as needed. Think Goldilocks and the subtleties in her choice of the ‘just right’ bed. Tweak the dosage until you find that sweet spot that works just right for your fur baby. Because of the chronic nature of the IVDD condition, we advise that you continue administering CBD daily in order to keep your pet pain free, relaxed, and comfortable.
About Hernando Umana
Father of Blanche, and 8-year old Shih Tzu and senior rescue Linda, Hernando Umana is a Broadway performer in New York City and works tirelessly to share the benefits of CBD with pet parents across the country. He graduated from Dr. Sulak’s Healer Cannabis Dosage Protocols and Methodologies. Despite his confidence and talent, Hernando found himself struggling after graduation. In a profession where anxiety is absolutely crippling, he wasn’t getting the kind of work he knew he should be getting. Thankfully, during one of his many visits to Angie in Florida, she introduced him to CBD and he has never looked back. Four years later, he had opened two first national tours, been on Broadway, worked with Cyndi Lauper, Brendan Urie, Andrew Loyd Webber, and many others. And now – Hernando is Co-Owner of CBD Dog Health. CBD was life-changing for both of them, and he could not be happier to be in a business doing something he loves so much that helps dogs like Blanche live a happy, stress-free life.
Getting real with CBD- a veterinary surgeon’s perspective
It was about the third week into Bastion’s recovery from his TPLO surgery, and he was already having a rough time. Bastion was a gregarious yellow Labrador who had injured his stifle about 25 days earlier. Fortunately, his family elected to have the stifle surgically reconstructed. Initially, he was recovering well from surgery, but one day in particular, he returned to the hospital because he’d had a brief setback. He was limping far more severely than would be normally expected at that stage of recovery.
Related: Get our guide to CBD
The osteotomy from his surgery had not yet completely healed, and he was still in the middle of his prescribed five weeks of strict exercise restriction. His family was trying their best, but Bastion wasn’t having it. He was too active at home, and his humans were growing frustrated. They’d received anti-anxiety medications but weren’t giving them. Instead, his family had decided to give him CBD oil at home. When I asked why, the client responded, “I found CBD oil at the local farmers’ market, and I figured it would work just as well.”
Like Bastion, an increasing number of pets are receiving cannabidiol (CBD) supplements. The popularity of CBD continues to rise, and many clients are incorporating it into the medication protocol for their pets, either as an adjunct or an alternative treatment option. Perhaps the initial interest in the benefits of CBD can be traced back to 1998, or possibly earlier, when scientists at the National Institutes of Health discovered that CBD could protect cells from oxidative stress.
These findings fueled interest in the human medical field and, in large part, that appeal has been transmuted into veterinary medicine. The regard for this molecule has risen to such levels that in many homes, CBD is being used as the sole treatment option for a variety of medical conditions. Veterinarians are becoming more fluent in the fascinating pharmacology regarding the use of this phytocannabinoid. A recent survey indicated that most veterinarians (61.5%) felt comfortable discussing the use of CBD with their colleagues, but only 45.5% felt comfortable discussing this topic with clients.1
Furthermore, veterinarians and clients in states with legalized recreational marijuana were more likely to talk about the use of CBD products to treat canine ailments than those in other states.2 Lastly, CBD was most frequently discussed as a potential treatment for pain management, anxiety, and seizures.1 At first glance, the use of CBD has tangential or limited relevance in the world of veterinary surgery. However, as one takes a closer look at the putative—and proven—benefits, it is clear that we are just scratching the surface of its therapeutic benefits.
Whether you perform surgery within a specialty discipline (oncology, orthopedics, neurology, soft tissue surgery, mixed animal, oral/dental, etc.), or surgery is only a small part of your general practice, every veterinarian endeavors to manage pain aggressively. The first choice for pain relief among many clinicians are the medications that have been more extensively studied, including but not limited to anti-inflammatories, gabapentinoids, opioids, local anesthetics, and other analgesics (acetaminophen, amantadine, Cerenia, etc.). These medications or a combination thereof have been prescribed to treat pain from orthopedic surgery, soft tissue surgery, intestinal surgery, and surgical neuropathic conditions, to name just a few. In the most basic schema, pain is divided into four categories: nociceptive pain (a response to damaged tissue), neuropathic pain (a response to directly-damaged sensory or spinal nerves), centralized pain (the result of pain signals being improperly amplified), and inflammatory pain.1
Cannabinoids may have a role to play in mediating all four of these types of pain states. When tissue is damaged, histamine, serotonin, TNF-alpha, IL-1-beta, IL-6 and Il -17 6 , and interleukin 17 are released.2 Cannabinoids bind to the CB1 receptors and attenuate the pain signal by slowing down the release of those neurotransmitters.3 This process can take place locally or in the central nervous system.3 Cannabinoids have also been shown to inhibit the release of GABA, a well-known neurotransmitter associated with pain.3 Although there is a paucity of clinical research on the use of CBD to treat postoperative pain in the veterinary medical setting, there has been heartening research conducted in humans. Indeed, the National Academies of Sciences, Engineering, and Medicine concluded that there is “substantial evidence that cannabis is an effective treatment for chronic pain in adults.”
Opioids have long been the go-to option or cornerstone of pain management, but the potential for the adverse events associated with the use of opioids in veterinary patients is universally accepted.38 I have seen how distressing it can be for a family to see their pet experiencing any of the unpleasurable side effects of opioids, including urine retention, delayed bowel movements, whining, panting, disorientation, or other manifestations of dysphoria. Those are just some of the challenges that clinicians face when using opioids for chronic pain management. Considering the ongoing consequences of the opioid epidemic, there is a search for pain management solutions that are innovative, prone to less adverse events, and are more effective. As the scientific community begins to evaluate the evidence for use of CBD, it is clear that more research is needed.
Anecdotal reports of CBD’s efficacy as a pain reliever are ubiquitous, but more practitioners are turning to scientific data for evidence of CBD’s efficacy. A study in 2020 evaluating effects of CBD hemp extract on opioid use and quality-of-life indicators in chronic pain patients found that over half of chronic pain patients (53%) reduced or eliminated their opioids within eight weeks after adding CBD-rich hemp extract to their regimens.5 Almost all CBD users (94%) reported quality-of-life improvements.5 A recent study evaluating orally consumed cannabinoids for long-lasting relief of allodynia in a mouse model found that cannabinoids reduced hyperalgesia, and a similar effect was not found with morphine.4 Mouse vocalizations were recorded throughout the experiment, and mice showed a large increase in ultrasonic, broadband clicks after sciatic nerve injury, which was reversed by THC, CBD, and morphine.4 The study demonstrated that cannabinoids provide long-term relief of chronic pain states.4 If research shows that use of cannabinoids in animals—specifically, CBD—can help to decrease the use of opioids for pain management, that would help make more animals comfortable and potentially help to fight the tragic epidemic of human prescription opioid abuse. Further research is needed in a variety of species, specifically, both the canine and feline species.
Both general veterinary practitioners and veterinary surgeons commonly diagnose and treat fractures. No large retrospective study of fracture incidence in dogs in North America has been published since 1994; however, the findings from that year’s study are still informative regarding the frequency of bone injuries. The study demonstrated that approximately 24% of all patients in the population studied over a 10-year period were affected by a disorder of the musculoskeletal system, with fractures contributing the largest proportion (over 29%) of all of the diagnoses of the appendicular skeletal system.7 Although that research is dated, the conclusions from this study, at the very least, indicate that fractures are commonplace in the clinical veterinary setting.7 Fracture repair has gradually become more straightforward due to improvements in technology. Because of these innovations, specialty surgeons and general practitioners who repair fractures have begun to see better surgical outcomes. So whether you primarily stabilize fractures with implants, or if external coaptation of fractures with the intention to refer (or perhaps as the primary means of fixation) is your treatment of choice, all veterinary practitioners aim to help fractured bones heal quickly. Despite these technological improvements, bone healing can be protracted or non-existent with some fractures. There are a variety of options at a veterinarian’s disposal to kick-start the healing process, but perhaps in the near future, CBD may be added to that armamentarium . The effect of CBD in fracture healing has been investigated evaluating bone callus formation in femur fractures in a rat model.8 The findings demonstrated enhanced biomechanical properties of healing fractures in those given CBD compared with a control group.8 This effect was not found in those given only Δ9-THC. Moreover, the bone-forming (osteogenic) effects of CBD were weakened when test subjects were given equal amounts of CBD and Δ9-THC.6 Another in vivo research study indicated that when CBD is incorporated into a surface that promotes bone growth (osteoconductive scaffold) it can stimulate stem cell migration and osteogenic differentiation.9 Further studies are needed to better evaluate the role of CBD in healing and bone metabolism of companion animals so that these findings can be applied in the clinical setting.
Additionally, cannabis has been shown to be a useful addition in treatment plans to improve bone health in laboratory studies. Studies have endeavored to better understand the role of CB2 receptors in maintaining bone health. CB2 receptors in bone cells have been linked to maintaining bone density and stimulating growth and may therefore have a part in reversing the effects of osteoporosis.10 One study evaluating the role of CB2 receptors found that mice whose genes had been altered to remove the CB1 or CB2 receptors developed signs of bone weakness that were far more pronounced than those in the control group.12 Another study in 2009 investigated the relationship between CB2 expression and bone disease in humans. It found that people with dysfunctional CB2 receptors have significantly weaker hand bones.11
Osteoarthritis (OA) affects many dogs, large and small. Most often, OA is the consequence of a developmental orthopedic disease that affects a single joint or a pair of joints and, less often, affects multiple joints. It is axiomatic that ‘Mother Nature likes symmetry,’ thus developmental orthopedic diseases frequently affect both left and right joints. For example, hip dysplasia is reportedly bilateral in >60% of affected dogs,13 and elbow dysplasia is bilateral in approximately 50% of affected dogs.14Osteoarthritis occurs secondary to a myriad of primary orthopedic conditions that affect a variety of joints including: the hip (most common causes of OA in the hip: hip dysplasia, Perthes disease); stifle (patellar luxation, cranial cruciate ligament disease, osteochondritis dissecans [OCD]); elbow (elbow dysplasia, elbow OCD, fragmentation of the medial coronoid process, incomplete ossification of the humeral condyle); shoulder (shoulder OCD, developmental shoulder subluxation); tarsus (OCD of the talus), and carpus (carpal laxity, carpal subluxation secondary to chondrodystrophy); and metacarpophalangeal (MCP) and metatarsophalangeal (MTP) joint degenerative osteoarthritis (digital osteoarthritis).
Cannabinoids were found to treat pain secondary to inflammation in a variety of studies on humans. Some of the most compelling research has shown that cannabis can reduce the inflammation in the joint caused in human patients diagnosed with immune-mediated arthritis.15 One study found that cannabinoids could simultaneously reduce the secretion of cytokines involved in inflammation from one type of TH immune cells, which were being under-produced, while also increasing their numbers to correct their scarcity.15 Furthermore, in a study in 2003, researchers found that plant-based cannabinoids could suppress the expression of interleukin-1beta—one of the most prominent markers for inflammation in patients with rheumatoid arthritis—by as much as 50%.16 And finally, in 2006, transdermal applications of CBD were shown to decrease biomarkers that can contribute to neurogenic inflammation in a sample of arthritic rats.17
A report published in The Journal of PAIN and written by researchers at Baylor College of Medicine revealed the results of a large, double-blinded, placebo-controlled study on the positive effects CBD had in the fight against osteoarthritis.18 The study was designed with two main goals: The first portion of the research studied the effect CBD had on the inflammatory molecules and cells in mice.18 The second portion of the study investigated whether CBD improved the quality of life in dogs diagnosed with osteoarthritis. In lab tests and in mouse models, CBD significantly decreased the production of natural chemicals that promote inflammation, and it increased the natural chemicals that fight inflammation.18 Essentially, they saw a drop in proinflammatory cytokines and an increase in anti-inflammatory cytokines.18 For dogs with osteoarthritis, CBD significantly decreased pain and increased mobility in a dose-dependent fashion. Importantly, a lower dose of liposomal CBD was as effective as the highest dose of non-liposomal CBD, indicating that the effect of CBD was quicker and more powerful when CBD was delivered encapsulated in liposomes than without.18 Blood samples indicated no significant harmful side effects or adverse events over the 4-week analysis period.18 Although this study is very promising, and it supports the safety and therapeutic potential of hemp-derived CBD for relieving arthritic pain in dogs, it is important to consult with your pet’s veterinarian before giving any supplement or medication.
In the veterinary population, use of cannabidiol and other alternative treatments has the potential to obviate the need for other medications and thus spare patients from adverse effects associated with their use. More likely, the use of cannabinoids could be additive or synergistic in a multimodal treatment strategy and could increase quality-of-life issues associated with painful arthritic conditions.
Intervertebral Disk Disease
As our patients age, discs in their spines undergo degenerative changes. Thus, degeneration of intervertebral discs is inevitable. This process of degeneration is multifactorial, and it involves hypoxia, inflammation, neoinnervation, accelerated catabolism, and reduction in water and glycosaminoglycan content.39 The magnitude and severity of disc degeneration can vary widely between patients. The most common locations of clinically relevant disc disease are the cervical spine, thoracolumbar spine, and lumbosacral spine.40 Although there are various manifestations of disc disease, broad classifications of Hansen Type I and Type II are typically used to describe the condition. In short, disc material may either extrude (acute herniations) or protrude (chronic herniations), both of which compress the spinal cord, which can ultimately cause pain, paresis, paralysis, and other neurological deficits.40 The prevalence of thoracolumbar disc disease in dogs has been estimated at 3.5%.40 Depending on the neurologic examination, diagnosis, severity, prognosis, and other factors, surgery may be recommended to decompress the spinal cord. After surgical decompression, there is a host of challenges that the patient, the family, and the surgeon may have to work through, including a potentially protracted recovery, recurrence of neurological signs, post-surgical pain, spinal instability, urinary disorders, (cystitis, urinary tract infection, urinary retention, micturition disorders), ascending myelomalacia, and others.41 Could CBD play a part in helping to improve those affected by disc disease pre-, intra-, or post-operatively, and what types of spinal disorders could benefit from CBD? A study conducted on the use of CBD in mice with degenerative disc disease showed promise in mitigating the effect of disc damage and wear.19 Instead of being ingested orally, CBD was injected at the site of the disc. Researchers investigated the effects of cannabidiol intradiscal injection using a combination of MRI and histological analyses.19 A puncture was created in the disc, and then CBD was injected into the disc (30, 60 or 120 nmol) shortly after.19 The effects of intradiscal injection of cannabidiol were analyzed within 2 days by MRI.17 Fifteen days later, the group that received cannabidiol 120 nmol was resubmitted to MRI examination and then to histological analyses after the cannabidiol injection.19 They found that cannabidiol significantly decreased the effects of disc injury induced by the needle puncture.19 These results suggest that this compound could be useful in the treatment of intervertebral disc degeneration, perhaps using a novel route of administration. Unfortunately, the exact mechanism for how CBD oil helped alleviate disc damage is still being investigated. The hope is that the neuroprotective properties of cannabidiol can also be found in the study of canine and feline disc disease to ultimately improve functional recovery.
Fortunately, more effort, research, and attention is being paid to treating pain in veterinary medicine.Nociceptive pain is caused by external pressure, cold, heat, or internal trauma, stimulated by the release of compounds like bradykinin, prostaglandins, or leukotrienes.20 Humans may describe this pain as a sharp, aching, or throbbing sensation. In veterinary patients, nociceptive pain may be manifested by limping, sharp movements, lip smacking, panting, vocalization, or, in select cases, no obvious response. The function of nociceptive pain in humans, and presumably in pets, is to alert them that they are injured and hopefully prevent further injury.20
Neuropathic pain, caused by direct damage to sensory or spinal nerves, allows aberrant pain signals to be sent to the brain.21 In veterinary patients, a common example of neuropathic pain that I diagnose commonly is sciatic or radial nerve hyperpathia, but lumbar or cervical foraminal radiculopathies can also be relatively frequent causes of neuropathic pain. Neuropathic pain syndromes are often secondary to intervertebral disc disease, static and dynamic nerve foramen impingement, vertebral instability, recent surgery, trauma, abnormal conformation, abnormal gait, and chronic joint pain.21 A classic example of neuropathic pain in humans is diabetic neuropathy.
Unfortunately, there are some challenges to diagnosing and understanding neuropathic pain in the veterinary setting, particularly in the presence of an otherwise normal orthopedic exam. To be sure, neuropathic pain can be evoked by low- or high-intensity stimuli; it can be spontaneous and not stimulus-dependent; it is maladaptive (maintained in the absence of tissue trauma), and it responds poorly to opiates and anti-inflammatory drugs.21
CBD use has shown promise in the treatment of neuropathic pain. In a 2010 study, researchers looked at a sample of diabetic rats and administered daily doses of Cannabis sativa ranging from 25 to 100 mg/kg [AC6] of body weight.22 After fourteen days, the rats exhibited significant reductions in tingling, heat, and pain in the extremities associated with advanced diabetes.22 Another study, from 2015, compared descriptions of spontaneous pain among sixteen patients with painful diabetic peripheral neuropathy in a randomized, double-blinded setting.23 The study subjects were administered four single-dosing sessions of placebo or cannabis. Significant reduction in pain intensity varied directly with the size of their dose.23
As we begin to understand neuropathic pain in animals more clearly, treatment strategies and pharmaceutical alternatives will more adequately address their pain, possibly including the use of CBD or CBD alternatives. Additional research will hopefully actualize the promise and potential that CBD may have in treating the veterinary population in neuropathic pain.
Exercise restriction is a critical component for successful surgical outcomes in many elective orthopedic surgeries. For example, post dynamic stifle stabilization surgery, I frequently recommend a minimum of five to eight weeks of strict monitoring and exercise restriction. This recommendation can be extremely challenging for families, because many of the animals are inclined to be active, are frequently powerful and athletic, and are young and unaccustomed to confinement. Implant failure or a poor surgical outcome overall can many times be ascribed to the challenges related to activity restriction. Difficulties with this process may lead to protracted recovery or even surgical treatment failure, necessitating a second surgical procedure.
Common pharmaceutical strategies employed to help with exercise restriction include the use of Trazodone and Acepromazine.24However, both of these medications can have variable effects depending on the individual, and in some cases, there are undesirable adverse effects (e.g. excessive sedation and paradoxical excitation with Acepromazine, serotonin syndrome with Trazodone, etc.).24
Could CBD or CBD derivatives enhance calmness and alleviate anxiety in animals? Based on CBD’s proposed mechanism of action in mitigating anxiety, the answer may be encouraging. Higher levels of natural endocannabinoids in the human body are associated with an antidepressant effect.25 Cannabinoid receptors are found throughout the central nervous system and play a key part in maintaining our sense of well-being. They are particularly numerous in cells tasked with manufacturing serotonin where it is needed.25
Cannabidiol may also have an effect on the hippocampus, which is a region of the brain responsible for memory and mood. Glucocorticoids are secreted during stress, which may cause the hippocampus to atrophy.26 That shrinking process plays a role in diminished memory and depressed mood.26 Cannabinoids have shown an ability to counter this process through the phenomenon of hippocampal neurogenesis (regrowth and development in nerve tissue), which can be activated by the expression of cannabinoid type-1 receptors.26 Both natural endocannabinoids and plant-based cannabinoids have both been shown to accelerate this process.26
In another random-controlled trial performed on humans, subjects receiving a 600 mg CBD supplement also reported less subjective anxiety symptoms during public speaking than those who’d taken a placebo.27 CBD also shows activity specific to the limbic system in the brain. A study evaluating that effect on the limbic system found that CBD administration helped to reduce symptoms in people with social anxiety disorder.28 Indeed, the National Academies of Sciences, Engineering, and Medicine specifically referenced CBD’s effects in a statement about anxiety disorders, “…there is evidence that cannabidiol is an effective treatment for the improvement of anxiety symptoms, as assessed by a public speaking test in individuals with social anxiety disorders.”30
A 2019 study in mice simulated to have an anxiety disorder, (Fragile X Syndrome—a neurodevelopmental disorder that affects intellectual, social, and physical development due to a mutation of the FMR1 gene) were shown to have fewer anxiety-related behaviors across tests when given CBD.31 Furthermore, CBD decreased the anxiety response of all mice tested while not affecting their cognitive performance.31
The potential for CBD to be efficacious in treating anxiety in other species will be important to study, but its use as an anxiolytic and sedative is growing in popularity despite the paucity of research specific to this indication. As previously mentioned, anxiety was one of the most common reasons for veterinarians to discuss CBD.1 The most commonly used CBD formulations were oil/extract and edibles1 for the putative benefits of relieving anxiety, among others.1 As CBD research continues to gain steam, more attention will hopefully be directed towards how the full ensemble of cannabinoids, terpenes, and flavonoids seem to complement each other, working through multiple receptors at once, and often enhancing each other’s signals to the body (entourage effect).
When it comes to wounds, all medical professionals are generally united in a common purpose: we want wounds to heal faster. Indeed, products that promote or accelerate wound healing have been of interest to veterinarians and physicians since the advent of wound treatment. Wound healing products and topical agents may target different phases of wound healing, including debridement, wound contraction, epithelialization, and granulation. Many products promote the formation of granulation tissue, while others are more effective after granulation tissue has formed (e.g. hyaluronic acid). For this reason, adapting the topical dressing specific to the stage and progress of wound healing is of utmost importance.
CBD has shown efficacy in the maturation phase of wound healing and some inflammatory skin conditions.33 In a 2019 study of 20 patients with two most frequent skin disorders—psoriasis (5 patients), atopic dermatitis (5), and resulting outcome scars (10)—the subjects were instructed to administer topical CBD-enriched ointment to lesioned skin areas twice daily for three months.33The results showed that topical treatment with CBD-enriched ointment significantly improved the skin parameters and the symptoms associated with the skin condition.33 This study concluded that the topical administration of CBD ointment, without any THC, is a safe, effective, and non-invasive alternative for improving the quality of life in patients with some skin disorders, especially inflammatory ones.33 Another study in 2019 investigated the potential effect of a Cannabis sativa L. ethanolic extract standardized in cannabidiol as anti-inflammatory agent in the skin.34 The study found that the extract inhibited the release of mediators of inflammation involved in wound healing and inflammatory processes occurring in the skin.34 The down-regulation of genes involved in wound healing and skin inflammation was at least in part due to the presence of cannabidiol.34 The findings provided new insights into the potential effect of Cannabis extracts against inflammation-based skin diseases.
Bacterial infiltration can negatively influence wound healing. Another area in which topical cannabis treatments show a great deal of potential is in the treatment of bacteria-related skin disorders. One study from 1976 indicated that isolates of THC and CBD were effective in reducing samples of staphylococci and streptococci, two bacteria associated with acne.35 Another study from 2008 found that the plant-based CBD, CBC, CBG, THC, and CBN were substantially potent against a variety of Staphylococcus aureus strains, which were resistant to the antibiotic methicillin (MRSA).36
However, a recent study perhaps underscores the importance of adjusting topical therapy according to the stage of healing. In 2020, the Australian Veterinary Journal reported a study on horses with wounds that were created in a laboratory setting and then deliberately contaminated. Each wound was assigned to a treatment group that contained 1% cannabidiol in three different manuka honey formulations.37 Treatments were applied topically daily for a total of 42 days. The results indicated that irrespective of the treatment, wounds did not retract as expected in the first seven days after wound creation.37 There was no difference in wound area, daily healing rate, or days to complete healing between treatment groups.37 This study highlights the importance for continued study on the correct time, concentration, and best practices when using CBD to accelerate wound healing.
Though the overall potential for cannabidiol to address specific surgical conditions is encouraging, strong double-blinded, placebo-controlled studies with large sample sizes are lacking. Based on the research that’s available in animal models and among human patients, there are large pockets of convincing research that inspire hope and promise in the use of CBD in veterinary surgery and veterinary medicine writ large. To be sure, the concept of scientific integrative medicine should be considered along with other first-line treatments for veterinary patients. Evidence-based solutions should be prioritized when treating disease, but innovative or novel treatments may have to be considered in patients with neuropathic pain, disc disease, anxiety, or debilitating arthritis. New discoveries in the world of cannabis-based medicine may be just what the doctor ordered for an effervescent Labrador like Bastion.
Kogan, L., Schoenfeld-Tacher, R., et al. (2018) US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions. Frontiers in Veterinary Science, 5:338.
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CBD Oil for Dachshunds
Your Dachshund is, without a doubt, the cutest dog on the block.
With her loving nature and charming looks, I know she gets constant attention from all your friends and family.
Unfortunately, due to their unique build, I’m sure you’re aware that Dachshunds suffer from specific health problems, especially back issues.
So, you’re probably looking for ways to help your Dachshund stay healthy, and have likely heard about CBD supplements.
In this article, I’m going to outline how CBD may help prevent some of the main health issues affecting Dachshunds.
This is our top choice for small dogs. It’s a 100% Organic Full Spectrum Oil that has received wonderful reviews of many pet owners.
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Despite their friendly appearance and character, Dachshunds were bred to be prolific hunters.
They were bred in Germany well before the 15th century and were originally a lot larger back then, weighing anywhere between 10-20 lbs.
They’d hunt anything from boar to rabbits, and were bred to make perfect, hard-working, and obedient hunting companions.
In the 19th century, Dachshunds became popular as pets, and were crossed with other breeds to create the smaller breed we know and love today.
Common Health Problem Affecting Dachshunds
Dachshunds are relatively healthy dogs, and can live up to 15 or even 20 years.
However, their peculiar build makes them prone to back problems, as well as arthritis or dysplasias.
Dachshunds are also prone to developing weight issues, which can lead to a variety of other problems.
Here is a list to review. Does your dog have any of these issues?
- Diabetes: Diabetes has many different causes. One of those is genetics, and this breed is believed to be slightly more prone to developing diabetes than some other breeds. Dachshunds are also prone to having weight issues, which is a leading cause of diabetes in dogs just like in humans.
- Eye Problems: Dachshunds are prone to developing a variety of eye conditions, including dry eye, cataracts, and Progressive Retinal Atrophy (PRA).
- Hip Dysplasia: Hip dysplasia is a genetic condition, meaning it is usually passed down from parents to their litter. It is characterized by a malformation of the hip joint, causing the bones in the joint to grind against each other.
- Intervertebral Disc Disease (IVDD) and other back problems: IVDD and other back problems are the #1 health concern for Dachshunds. Unfortunately, due to their breeding, roughly 1 in 4 Dachshunds develop IVDD at some point in their life.
- Obesity: Dachshunds are notorious for struggling to manage their weight. This is generally caused by a poor diet, overeating or a lack of exercise, but can also be the result of an underlying condition like hip dysplasia or arthritis, which might leave a dog avoiding physical activity.
- Patellar Luxation: Patellar luxation happens when the knee is not formed properly, which causes it to dislocate on a regular basis. While it doesn’t cause acute pain, it usually leads to arthritis.
- Skin Issues: Dachshunds are fairly prone to developing skin diseases. Acanthosis nigricans, for example is unique to the Dachshund.
How Can CBD Help My Dachshund?
Reading about your dog’s potential health problems is no fun.
But remember, there are plenty of options out there to help you improve your Dachshunds condition if they happen to suffer from one of these ailments.
One of those options is CBD, or cannabidiol, a natural, plant-based compound found in cannabis and hemp plants.
Below I’m going to look at 2 common conditions affecting Dachshunds.
But before I get started, you’re probably wondering who I am.
My name’s Blake, and only a few years ago I was in a similar position to you:
My dog Rosie, a gorgeous Golden Retriever was diagnosed with Cancer.
The poor girl was already dealing with hip dysplasia and it eventually caused her to develop arthritis as well.
Following Rosie’s cancer diagnose, I was set on helping her enjoy her remaining years to the fullest.
This is when the topic of CBD came across my desk.
Obviously, I wasn’t convinced from the get-go.
In fact, I was more than hesitant to give my dog Rosie a medicine derived from “pot.”
But, I learned that CBD is a completely safe, compound that causes no side effects.
And, most importantly, it’s non-psychoactive, meaning it won’t get your pooch “high.”
Today, I’m so glad I decided to try CBD.
Within only a few days of trying it, Rosie’s condition improved immeasurably.
It was so obvious she was in less pain, but she also became more active and regained her appetite (which was always a little off following a her chemo treatments).
Best of all, I was able to extend her life well beyond my vet’s original estimates.
Now, I want to help other pet owners learn about the huge potential of CBD.
So, here are 2 ways you can also harness the health benefits of CBD for specific ailments popular in Dachshunds.
Remember, CBD has many different health benefits, not just the ones I outline below.
CBD for Dachshunds With Back Problems
Back problems are the #1 health concern for Dachshunds.
The most common back problem affecting Dachshunds is IVDD (Intervertebral Disc Disease), which is estimated to affect around 25% of all Dachshunds at some point in their life.
IVDD is caused when a inter-vertebral disc bursts or herniates and bulges out of its original position.
Over time, these discs become hard, brittle, and begin pushing on surrounding tissue, including nerves.
The most obvious symptoms of IVDD are pain and lameness, especially in the affected part of the back and the hind legs.
Your dog may also cry out in pain as a result of IVDD, or experience other symptoms, including:
- Hunches in the back or neck
- Unwillingness to jump and avoidance of physical activity
- Loss of bladder or bowel control
- Reduced appetite
- Lack of energy
IVDD is treatable, but the exact treatment your dog undergoes will vary depending on their exact condition.
In mild cases of IVDD, your vet will usually go for palliative treatment designed to minimize your dog’s pain while maximizing their ability to live a normal life without causing further damage to the spine.
In more serious cases of IVDD, your vet may decide to operate on your dog.
If your Dachshund suffers from IVDD and you’re looking for a natural way to control his/her pain, I highly recommend using CBD, especially as an alternative to regular pain medications.
Studies show that CBD is a natural painkiller and anti-inflammatory.
By stimulating your dog’s endocannabinoid system (a physiological system involved in managing everything from pain to memory and sleep), pain signals or “triggers” to the brain are reduced while also actively fighting inflammation around the body.
This is why CBD has become such as popular treatment option for people and animals suffering from arthritis.
Plus, the fact that CBD produces no side effects makes it especially attractive.
Most regular pain medications prescribed to dogs (like Metacam and Rimadyl, for example) can cause side effects, including:
- Black, tarry or bloody stools or diarrhea
- Increased or decreased activity
- Skin irritation
- Stomach ulcers
- Unexpected weight loss
- Loss of appetite
- Abdominal pain
- Liver and kidney damage
I used CBD with my dog Rosie to manage the inflammation and pain caused by her hip dysplasia and arthritis.
Her condition had left her acting lethargic and lazy, which was not like the Rosie we knew at all.
She was always an active dog that loved to play, go for runs, and swim.
Occasionally, she’d also whimper or cry out in pain after performing some kind of activity/movement that especially hurt her hip or legs.
Once we started using CBD, however, that all changed. Many pet owners report the exact same thing as well.
Within just a few days, we noticed huge improvements to her condition.
She immediately became more active around the house and seemed to struggle less when getting up/laying down, or jumping up on the couch.
As we continued her treatment, she only improved further.
Within a few weeks, she was joining us on walks and back to playing in the park with her other fury friends.
If your dog suffers from IVDD, I highly recommend you try CBD to help manage his/her painful symptoms as well as control any inflammation that may be forming around their affected discs.
If, as a result of IVDD, your dog develops arthritis (which is very common), I also recommend using CBD to manage their pain and inflammation.
CBD for Dachshunds With Diabetes
There are many causes of dog diabetes.
Some common causes include:
- Genetics (certain breeds, like Dachshunds, are more prone to developing diabetes)
- Autoimmune conditions
- Certain medications
If your dog deals with diabetes, you’ll want to control their condition immediately.
Your vet will be able to help you do this, usually using certain medications, insulin injections, dietary/lifestyle changes.
While it is a serious health condition, dog diabetes is pretty manageable in a way that still lets your dog live a relatively normal life.
If your Dachshund pup deals with Diabetes, I highly recommend trying CBD oil.
In 2015, an Israeli company began developing CBD-based diabetes treatments after numerous studies showed that the compound could help treat and prevent the disease.
Studies suggest CBD can help fight diabetes in numerous ways, mainly by fighting the chronic inflammation seen in patients with type 2 diabetes, promoting immune health and metabolic processes.
Now, I know what you’re thinking:
“These studies are based on lab rats or humans, so how can I be sure my dog will react to CBD the same way?”
Well, while your dog’s anatomy may be different to yours, he/she actually has the exact same endocannabinoid system as you do.
This means they can benefit from CBD in much the same way as humans or other mammals.
Hence, if your dog suffers from diabetes, I highly recommend trying a CBD-rich pet supplement such as King Kanine CBD oil or treats.
I’ve also had success with Canna-Pet supplements and recommend them as well.
Are Other Small Dogs Seeing Results With CBD Products?
I’m not the only pet owner sharing the awesome results of CBD.
There are pet owners EVERYWHERE who use these supplements to help their dogs, cats, and even horses with everything from anxiety and behavioral issues, to cancer.
Deuce, for example, is a Dachshund whose owners use CBD capsules and oil to treat his diabetes, anxiety, and joint pain.
Screenshot taken from Canna-Pet.com
Like many other Dachshunds, Deuce had back issues as well, and his owners believe his symptoms have been reduced through the use of CBD supplements.
Chili used CBD to help with his cancer.
Screenshot taken from Canna-Pet.com
He used CBD treats and cookies to keep him happy through his last few years. His owners believe these biscuits helped make his remaining time as enjoyable as possible.
Another example is Erin, a Dachshund – Scottie mix.
Screenshot taken from Canna-Pet.com
She suffers from arthritis and had a lot of pain just walking. After using CBD, she’s almost running again! Her owners are extremely happy with the results these supplements have had in regards to her pain and inflammation.
Which Product is Best for Smaller Pets
Over the years I’ve tested out quite a few different brands.
I personally feel some performed better than others, and certain companies offer much better value when shopping online.
As of today, my top recommendation comes from a company that we’ve been using for quite some time: King Kanine.
They have a bunch of products, however their King Kalm CBD 300mg RX offers the best value.
For small dogs like Dachshunds, this particular oil should last you long enough to see some positive results.
If you want more specific details on our experience with these products, you can head over to my King Kanine review for more details.
If your pup is not feeling so great right now, I hope CBD can help!
Hey I’m Blake, the founder of this website. Our family was fortunately to have discovered CBD products after our dog Rosie was diagnosed with a few common ailments. I truly believe they enhanced her last few years, and it’s my passion to spread the word through this website. Thanks for visiting!