cbd oil for anxiety how long to work

Can You Overdose on CBD?

Cannabidiol (CBD) oil is growing in popularity, mostly due to recent legalization and its frequently touted effectiveness in treating common ailments. CBD is used as treatment for a wide range of illnesses and ailments. Unfortunately, most people are unaware of which dose is best. The responsible use of CBD oil to achieve the best possible results requires awareness of its composition and proper dosage so that too much CBD is not ingested.

Can You Overdose on CBD?

The answer to this question is likely a version of “yes,” although an overdose is not life-threatening as it can be with other substances. It is estimated that an average male who weighs 180 lbs would need to ingest more than 33 tablespoons of CBD oil in one sitting to qualify as “overdosing” on CBD. As further perspective, a typical dose is 1/8 of a teaspoon.

That said, while it may be hard to overdose on CBD, this should not be misconstrued as meaning that high amounts of CBD are somehow harmless. (After all, as with any medicinal substance, the packaging directions regarding recommended dosage are not arbitrary: They are there for a reason.) If you experience severe effects after taking an inordinate amount of CBD, seek immediate medical attention.

Anyone who regularly uses CBD for pain or other issues needs to know they are taking a correct and safe, therapeutic dose of CBD, based on factors such as:

  • Body and Weight. Appropriate CBD levels are partly based on metabolism and body weight.
  • Biphasic Action. Lower doses of CBD have certain effects and higher doses have other effects. It is important to consider what ailments the CBD is intended to treat to identify the correct dosage.
  • Form of CBD. The most common form is CBD oil or tincture, but other forms such as gummies and vape juice are also used. Dosage depends on the form of CBD consumed.

The Effects CBD Can Have on the Body

Although CBD is one of 100 chemical compounds found in the cannabis plant, it is not psychoactive, like THC. This quality makes CBD a promising option for chronic pain relief and anxiety. CBD works by changing the receptor activity of the body’s endocannabinoid system (ECS), which regulates functions such as sleep, pain response, and the immune system.

Does Taking More CBD Reduce Anxiety Even More?

Anxiety and depression are devastating mental health disorders that are all too common. People who have sought treatment for anxiety but are not comfortable with pharmaceutical drugs have turned to CBD oil as a promising treatment. CBD has also been used to treat addiction.

A Brazilian study set out to measure anxiety levels when 57 men received either oral CBD or a placebo— 90 minutes before participating in a simulated public speaking contest. The results revealed that a 300-mg dose of CBD significantly reduced the men’s anxiety. Interestingly, both the placebo, a 150-mg dose of CBD, and a 600-mg-larger dose of CBD had little to no effect on anxiety.

This study and others like it reveal that more is not necessarily better when it comes to CBD. Identifying the proper dose is imperative for achieving the desired results. Different individuals can react to different doses in varying ways.

CBD and Pets

While there is no definitive research that shows how CBD affects dogs and other pets, pet owners have plenty of anecdotal evidence based on treating their animals for pain, seizures, and even depression. The AKC Canine Health Foundation is currently sponsoring research into the effects of CBD for treating epilepsy in dogs and is hopeful that beneficial discoveries will come of this effort.

CBD Is Becoming Popular for Pets – Why and How It Works

CBD works the same on a dog’s ECS as it does on a human. Pet owners who have struggled to find a viable remedy for their pets’ ailments have turned to CBD. Although the safety and risks of using CBD for dogs have not been researched, it is known to have the following side effects:

  • Dry mouth. CBD decreases the production of saliva which causes increased thirst.
  • Lowered blood pressure. Temporary drops in blood pressure can occur when doses are too high.
  • Drowsiness. The calming effect of CBD helps with anxiety but can also cause drowsiness.

Can Pets OD on CBD?

A commonly asked question is “What happens if my dog eats CBD?” The truth is that the safety and risks associated with dogs ingesting CBD have not been researched. The FDA has not approved CBD for dogs, so there is no regulated dosing. It’s not known exactly how much CBD is toxic for dogs. If a dog accidentally ingests any amount of CBD oil, it is best to seek treatment from a vet.

CBD and Children

Parents will go above and beyond for their children, especially when their children are in pain or suffering from other ailments. Although some doctors recommend CBD oil for children, citing numerous benefits, it is important to understand that a child’s body can react differently to a substance that works well for an adult.

Not only are dosages different to account for a child’s smaller and less developed body, but the manner in which CBD is ingested is different as well. Children obviously will not be vaping or dabbing CBD concentrates, so other methods of ingestion, such as gummies or placing CBD oil under the tongue are necessary.

If your child has consumed too much CBD and you are concerned, contact poison control immediately. CBD is a legal compound that can be toxic in large doses, similar to soap or toothpaste. Erring on the side of safety is best, especially considering that there is still much to learn about the potentially harmful properties of CBD taken in high quantities.

How Long Do the Effects of CBD Take to Wear Off?

The answer to this question depends on many factors such as the dose and a person’s metabolism. In general, it can take 5-20 minutes for the effects of CBD to manifest and these can last 2-4 hours. A big factor affecting how long CBD’s effects last is the method of ingestion and whether a CBD user ingests edible gummies, a capsule, a tincture, or a food product laced with CBD. Vaping, the most common way to consume CBD, begins to work within five minutes, but also subsides fairly quickly. The effects of topical CBD can take longer to kick in but also tend to last longer.

CBD oil has been studied for its potential role in easing symptoms of many common health issues in adults, including anxiety, depression, acne and heart disease. However, not much research exists addressing the toxicity of CBD or whether adults, children, or pets can overdose on CBD. Research on the potential health benefits and risks of CBD oil is ongoing. While CBD is generally regarded as a safe and effective way to manage pain and anxiety, CBD is still a medicinal substance that should be taken according to the dosing instructions on the packaging label.

About Kristina Robb-Dover

Kristina Robb-Dover is a content manager and writer with extensive editing and writing experience. read more

CBD for anxiety and depression – does it work?

Interest in CBD (cannabidiol) for the treatment of anxiety and depression has grown in popularity in recent years, especially since the introduction of the 2018 Farm Bill in the US, which allows people to legally buy products containing CBD under federal law.

CBD is a chemical found in the Cannabis sativa plant. THC (delta-9-tetrahydrocannabinol) is another active compound found in cannabis, which is also known as marijuana. THC is well-known for making people ‘high’, but CBD does not produce the same intoxicating effects.

CBD is of interest in the treatment of anxiety and depression because:

  • CBD appears to be safe and generally well-tolerated
  • Studies conducted in animals suggest it may be effective for anxiety and depression
  • The current treatments available for anxiety and depression aren’t always effective

People are using CBD, but the evidence supporting its use is limited

A national survey conducted in the US in 2019 revealed that people are most commonly using CBD to reduce pain, stress and anxiety, and to improve sleep.

A review conducted by the National Academies of Sciences, Engineering and Medicine, however, has found limited evidence that CDB can improve symptoms of anxiety in people with social anxiety disorders. This result doesn’t mean that CDB isn’t effective, it just means that more work needs to be done to better understand the potential role of CBD in the treatment of anxiety.

The evidence supporting the use of CBD in depression is even more limited than that available for anxiety.

CBD and anxiety – what the clinical research shows

One dose of CBD reduced anxiety in people with SAD

One dose of CBD reduced anxiety in men with generalized social anxiety disorder (SAD) in two small studies. Study participants reported feeling less anxious during a public speaking test in one of the studies, and experienced a reduction in cognitive impairment.

The other study reported that participants felt less anxious and also showed that CBD caused changes in regional cerebral flow. CBDs was thought to have an effect on the limbic and paralimbic areas of the brain. These areas are involved in processing of emotional information.

The studies were double-blind, randomized, placebo-controlled studies, which investigated a single dose of a capsule containing either 400mg or 600mg of CBD.

Longer-term use of CBD also helped to reduce anxiety symptoms

CBD taken for four weeks significantly reduced anxiety in a small group of Japanese teenagers who suffered from social anxiety with avoidant personality disorder in another small study.

Treatment with capsules containing CBD 25 to 50-75mg a day for 1-3 months also helped to improve anxiety symptoms and caused fluctuating improvements in sleep disturbances, according to an analysis of patient records. The records of 72 psychiatric patients with anxiety and sleep problems were analyzed.

CBD has potential as an add-on therapy in people with anxiety disorder

CBD may have potential as an add-on to cognitive-behavioral therapy (CBT) in people with anxiety disorder, particularly post-traumatic stress disorder (PTSD), according to a small study in which it was shown to enhance ‘extinction learning’.

Extinction learning refers to the process whereby there is a gradual decrease in the response to a stimulus, such as an event that causes fear or anxiety, by learning to associate that stimulus with a different response.

CBD helped to lessen a fearful response in participants in this study. Adding CBD to behavioral therapies for the treatment of anxiety may enhance the effectiveness of these techniques.

PTSD symptoms were also reduced, especially for those who suffered from frequent nightmares, in a study conducted in 11 participants with PTSD. Participants took CBD capsules or liquid spray, starting at doses of 25-48.64mg a day, for 8 weeks.

CBD and depression – what the clinical research shows

Clinical research investigating CBD in patients with depression is limited

Much of the research has looked at products containing both CBD and THC, such as nabiximols (Sativex), which is approved outside of the US to treat spasticity in patients with multiple sclerosis. One such study showed that a 6-day regimen of nabiximols helped to reduce depression during cannabis withdrawal.

In another study conducted in patients who were still regularly using cannabis, treatment with CBD 200mg a day was reported to have a restorative effect and significantly increased left subicular complex volume, particularly in the brains of heavy cannabis users. The researchers reported that the results indicate that CBD might be useful as an add-on therapy in the treatment of major depressive disorder (MDD) and other disorders. The study was conducted over about 10 weeks in 18 people who were regular cannabis users.

Clinical trials are underway or set to begin in patient with depression

In March 2021, a clinical trial was being conducted to investigate CBD 150-300mg a day for 12 weeks in 100 patients with bipolar depression. The study is expected to be completed in April 2022.

Another trial is also expected to begin to investigate the use of Epidiolex in 10 patients with treatment-resistant MDD. Epidiolex is an FDA-approved oral solution containing CBD, which is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome or tuberous sclerosis complex in patients one year of age or older.

How CBD works in anxiety and depression

CBD acts on more than 65 key targets in the body, including the endocannabinoid system and serotonin (5-HT) 1A receptors.

The endocannabinoid system is a biological, cell signaling system, which CBD acts on. This system plays a role in the regulation of many factors including appetite, memory, mood, pain, inflammation, the immune system and more.

5-HT1A receptors are also a key target for current anxiety and depression treatments.

Exactly how CBD works in anxiety and depression, and which targets are key to its anxiolytic and antidepressant effects, is still being investigated.

Further research is required

Current research suggests that CBD has potential in the treatment of anxiety and depression. Further research is needed, however, including larger and longer-term randomized, controlled trials to fully understand what role CBD will play in the treatment of these conditions.

Remember to consult your healthcare professional before using CBD for anxiety or depression.