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Medical cannabis can reduce essential tremor by turning on overlooked cells in the central nervous system. Injecting a specific synthetic cannabinoid into the spinal cord of mice suffering from essential tremor reduces involuntary shaking by activating astrocytes.

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How do they get mice with essential tremor

The article didn't state specifically, but most likely drug induced.

Of the animal models with extensive tremor characterization, harmaline-induced rodent tremor models provide an important framework showing that rhythmic and synchronous neuronal activities within the olivocerebellar circuit can drive action tremor.

Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature.

I know 6-hydroxydopamine is used to induce Parkinson’s in rats.

Dopaminergic toxins can be used are often the most used drugs to produce movement-related disorders. MPPP is an example of a substance capable of inducingirreversible parkinson symphtoms.

I have it; I’ll conduct my own experiments and report back.

A bit misleading on the title. is "cannabis" and a "synthetic cannabinoid" actually the same thing?

No. Insanely misleading.

It's not even a synthetic cannabinoid in the true sense, as it has nowhere near the same structure. It's a synthetic "cannabimimetic" that kinda mimics phytocannabinoids, but not really. This title is whack.

Most scientific articles that gain traction on Reddit are misleading

You ready to inject some weeed

Really really misleading. The molecules are classified this way due to being active at the cannabinoid receptors. "Fun" fact: most of the synthetic cannabinoids are extremely deadly and they are active at the few units of miligrams. They are also highly addictive and can produce severe physical withdrawals. A lot of people have died using them due to this false impression given by the word "cannabinoid".

Also another mouse study. A lot of good ideas never survive the transaction from mice to humans.

A spinal injection into mice of a synthetic cannabinoid did “xyz” is a long long way of from, Aunt Jude’s hash brownies cured my whatever.

This is one of those American "weed culture" posts that tries to promote weed as a 100% cure all.

There are definitely upsides but I have yet to recommend it as a treatment to any of my patients not out of spite but rather clear and definitive research demonstrating strong drawbacks and fallacies.

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