cbd oil for interstitial lung disease

E-cigarette, or Vaping Product, Use Associated Lung Injury (EVALI)

In the summer of 2019, the Centers for Disease Control and Prevention (CDC) began to investigate a steep rise in hospitalizations linked to the use of vaping products. The patients complained of a host of respiratory symptoms including shortness of breath, cough, and chest pain. They all shared one thing in common: They had used vaping products within the previous three months.

The condition came to be called “e-cigarette, or vaping, product use associated lung injury,” or EVALI. By February 2020, the CDC had recorded over 2800 hospitalizations due to EVALI along with 68 deaths caused by the condition.

Fortunately, there has been a substantial drop in cases since they peaked in August and September of 2020. What’s more, researchers have also identified vitamin E acetate, a chemical added to some THC-containing vaping products, as the main—but possibly not the only—cause of the illness. The outbreak of EVALI cases emerged against a backdrop of an ongoing vaping epidemic among youth. According to the CDC, 15% of EVALI patients were less than 18 years old.

At Yale Medicine, most pediatricians have started asking middle- and high school-age patients about their exposure to vaping, in large part to identify patients who might be at higher risk for developing related problems.

“I screen all of my patients, any child over age 12, since [vaping] can exacerbate underlying conditions like asthma,” says Yale Medicine pediatric pulmonologist Pnina Weiss, MD.

What is EVALI?

EVALI is a serious medical condition in which a person’s lungs become damaged from substances contained in e-cigarettes and vaping products.

Vaping involves using a device known as an e-cigarette—but also called a vape pen, mod, or tank—to heat up a small amount of liquid, turning it into a vapor that can be inhaled. Most vape liquids contain substances such as propylene glycol and glycerol as base ingredients that create the vapor. But they may also contain other compounds including artificial flavors, nicotine, THC, and cannabinoid (CBD) oil.

What are the symptoms of EVALI?

EVALI may cause the following symptoms:

  • Shortness of breath
  • Cough
  • Chest pain
  • Fever and chills
  • Diarrhea, nausea, vomiting, and abdominal pain
  • Rapid heartbeat
  • Rapid and shallow breathing

What are the causes of EVALI?

Researchers have linked vitamin E acetate, a synthetic form of vitamin E found in some THC-containing vaping products, to EVALI. When inhaled, the chemical can damage the lungs. One study detected vitamin E acetate in the lung fluid of 48 out of 51 EVALI patients sampled across 16 states. By contrast, lung fluid samples taken from healthy people did not contain the vitamin.

Because of this and other studies, vitamin E acetate is considered the main cause of EVALI. Other chemicals found in nicotine- and THC-containing vaping products may also play a role in the condition.

What are the risk factors of EVALI?

The primary risk factor for EVALI is current or previous use of a vaping device.

In particular, use of vaping devices that contain THC have been associated with the condition. According to the CDC, over 80% of people hospitalized due to EVALI reported use of vaping products that contained THC, though many also said they used nicotine-containing products. The CDC further notes that nearly 80% of EVALI patients who used THC-containing e-cigarettes obtained their vaping products from “informal sources” including family, friends, dealers, or online sources, rather than commercial outlets.

How is EVALI diagnosed?

Diagnosing EVALI can be challenging because the symptoms of this lung condition are similar to those of other respiratory illnesses, like pneumonia and even the seasonal flu virus.

What’s more, there is no single test for EVALI. It’s what is known as a “diagnosis of exclusion,” which means that a doctor will conduct tests to rule out other potential diseases and conditions.

Your doctor will begin his or her diagnosis by asking you about your use of e-cigarettes within the past three months and whether you vaped a product containing nicotine, THC, or both. During the physical exam, your doctor will use a stethoscope to listen to your lungs, check your heartrate, and measure your blood oxygen saturation using a pulse oximeter. A chest X-ray or computed tomography (CT) scan is usually necessary for diagnosis and will show hazy looking spots (called opacities) in the lungs. This contrasts with a clear back space in healthy lungs. Your doctor may also order bloodwork to rule out other possible causes of your illness.

What is the treatment for EVALI?

Many people diagnosed with EVALI need to be treated in a hospital where medications can be closely monitored, and respiratory support is readily available.

Treatments may include:

  • Corticosteroids. A type of medication that reduces inflammation in the lungs and throughout the body.
  • Supportive care. Patients may receive supplemental oxygen through a nasal cannula. In more severe cases, they may be put on a mechanical ventilator or an extracorporeal membrane oxygenation machine.
  • Antibiotics. These drugs may be given to the patient while diagnostic test results are being finalized as it’s difficult to distinguish EVALI from bacterial infections.
  • Antivirals. Because EVALI causes similar symptoms to some viral infections, antivirals may be used, especially during influenza season.

What is the outlook for someone with EVALI?

Because the illness is so new, there is no way to predict how patients will fare after being released from the hospital following treatment. Dr. Weiss says that some have become ill again after steroid treatment is stopped, so follow-up care is vital.

“We recommend that patients see a pulmonologist within one to two weeks after being discharged to undergo testing of lung function and pulse oximetry [level of oxygen in the blood],” she says.

Because of the lack of long-term data and the fact that patients have died from EVALI, the prognosis for those affected remains uncertain. Researchers are working hard to learn as much as possible about the illness, its causes, and the odds for making a full recovery.

How is Yale Medicine unique in its approach to EVALI?

“Yale physicians have been at the forefront in identifying EVALI cases,” Dr. Weiss says. She explains that even before CDC guidelines on treating the illness were released, Yale doctors were successfully treating patients with a combination of antibiotics and steroids. Doctors at Yale Medicine also collaborate with researchers in the fields of tobacco and addiction medicine to provide care for patients with EVALI.

Interstitial Pneumonia

What does interstitial pneumonia mean?
1. chronic lung disease affecting the interstitial tissue of the lungs
Interstitial pneumonia is a disease in which the mesh-like walls of the alveoli become inflamed. The pleura (a thin covering that protects and cushions the lungs ).

Interstitial pneumonia ( NSIP) is a rare disorder that affects the tissue that surrounds and separates the

Interstitial pneumonia

noun chronic lung disease affecting the interstitial tissue of the lungs.
Interstitial pneumonia: Another name for Interstitial lung disease (or close medical condition association).

Interstitial pneumonia: Related Diseases
Interstitial pneumonia: Interstitial pneumonia is listed as a type of (or associated with) the following medical conditions in our database:

  • Respiratory conditions
  • Lung conditions
  • Pneumonia
  • Chest conditions
Causes of Interstitial pneumonia

Some of the causes of Interstitial pneumonia are included in the list below:

  • Pulmonary fibrosis
  • Lymphocytic interstitial pneumonia
  • Desquamative interstitial pneumonitis
  • Coin lesion (chest x-ray)
  • Pneumonia
Symptoms of Interstitial pneumonia (Interstitial lung disease)

Some of the symptoms of Interstitial pneumonia include:

  • Fever
  • Fatigue
  • Muscle pain
  • Joint pain
  • Abnormal chest sounds

These medical disease topics may be related to Interstitial pneumonia:

  • idiopathic pulmonary fibrosis
  • restrictive lung disease
  • idiopathic fibrosing alveolitis

Terms associated with Interstitial pneumonia:
Broader terms for Interstitial pneumonia

  • respiratory disease
  • respiratory illness
  • respiratory disorder
Hierarchical classifications of Interstitial pneumonia

The following list attempts to classify Interstitial pneumonia into categories where each line is a subset of the next.

  • respiratory disease,respiratory disorder,respiratory illness
  • disease
  • illness,malady,sickness,unwellness
  • health problem,ill health,unhealthiness
  • pathological state
  • condition,status
Interstitial lung disease/ Interstitial pneumonia

Description of Interstitial pneumonia
Interstitial pneumonia (medical condition): A category of chronic lung diseases characterized by scarring and/or inflammation of the lungs.
Interstitial pneumonia: chronic lung disease affecting the interstitial tissue of the lungs.

Background

Interstitial pneumonias are a confusing and frustrating set of diseases both for the treating physician and for the diagnostic pathologist. One source of the confusion has been the lack of overlapping terms that treating physicians and pathologists use. For example, idiopathic pulmonary fibrosis (IPF) is a clinical term describing a slowly progressive, chronic interstitial pneumonia. Since many of the interstitial pneumonias, including UIP, DIP, and NSIP, fall under this category, it is a non-specific term. Most pathologists who are experts in lung pathology use the terms IPF and UIP to mean the same disease process. To complicate matters even further, European clinicians utilize the term cryptogenic fibrosing alveolitis for IPF. Pathologists also share in the confusion. Terms that were commonly used by pathologists just a few years ago have also undergone an evolution. Bronchiolitis obliterans with organizing pneunomina (BOOP) is no longer used because it has been considered a mixture of terms. Lymphocytic interstitial pneumonia (LIP) is now considered a lymphoproliferative disease. Giant cell interstitial pneumonitis (GIP) is now considered a hard metal pneumoconiosis.

The symptoms vary for each of the pneumonias but most are characterized by a slowly progressive shortness of breath. Chest radiographs reveal a hazy ground glass appearance with linear opacities. Most of the diseases are progressive and are treated with corticosteroids.

Usual interstitial pneumonia (UIP) is a form of lung disease characterized by progressive scarring of both lungs. The scarring (fibrosis) involves the supporting framework (interstitium) of the lung. UIP is thus classified as a form of interstitial lung disease. The term “usual” refers to the fact that UIP is the most common form of interstitial fibrosis. “Pneumonia” indicates “lung abnormality”, which includes fibrosis and inflammation. The term used for UIP in the British literature is cryptogenic fibrosing alveolitis, a term that has fallen out of favor since the basic underlying pathology is now thought to be fibrosis, not inflammation.

Causes

The cause of the scarring in UIP may be known or unknown. The latter situation is more common. Since the medical term for conditions of unknown cause is “idiopathic” the clinical term for UIP of unknown cause is idiopathic pulmonary fibrosis (IPF). Examples of known causes of UIP include systemic sclerosis/scleroderma, rheumatoid arthritis, asbestosis and chronic nitrofurantoin toxicity.

Symptoms

The typical symptoms of UIP are progressive shortness of breath and cough for a period of months. In some patients, UIP is diagnosed only when a more acute disease supervenes and brings the patient to medical attention.

Prognosis

Regardless of etiology, UIP is relentlessly progressive, usually leading to respiratory failure and death. Some patients do well for a prolonged period of time, but then deteriorate rapidly because of a superimposed acute illness (so-called “accelerated UIP”). The outlook for long-term survival is poor. In most studies, the median survival is 3 to 4 years. Patients with UIP in the setting of rheumatoid arthritis have a slightly better prognosis than UIP without a known cause (IPF).

How is interstitial lung disease treated?

The choice of treatment depends upon a number of factors including the cause of the interstitial lung disease and the overall health status of the patient. Most commonly, corticosteroid drugs are given in an attempt to reduce the inflammation. Sometimes, immune-suppressing drugs, such as asazathioprine (Imuran) or cyclophosphamide(Cytoxan) are also given, either in combination with steroids or following a course of steroid treatment. Some patients with interstitial lung disease benefit from oxygen therapy and/or respiratory therapy (pulmonary rehabilitation) to improve daily functioning. Smoking cessation is critical for those with interstitial lung disease. Finally, in severe cases, lung transplantation may be considered in certain patients.

Pneumonia

What is pneumonia? Pneumonia is an infection of the tiny air sacs of the lungs. There are many different types of pneumonia, which can range from mild to severe.

The symptoms vary for each of the pneumonias but most are characterized by a slowly progressive shortness of breath. Chest radiographs reveal a hazy ground glass appearance with linear opacities. Most of the diseases are progressive and are treated with corticosteroids.

An incurable, deadly lung disorder.

Medical Marijuana

Medical marijuana should never be smoked by anyone with lung problems. My suggestion is that you acquire a Sativa x Indica hybrid and then make yourself a whole plant tincture. Place a drop under the tongue twice a day to start. Increase when necessary.

I also recommend edibles made from good cannabutter. These you should also make yourself using: leaves, petioles, and (bud) shake/ trimmings and unsalted butter. Or if making an oil: use good quality olive oil, grapeseed oil, etc.

There are articles on our website: Acquire organically grown medical marijuana (free of any pathogens). Make your own whole plant extracts. This way you will be taking the best medicine possible. (you can heat the medical marijuana in your oven–302 degrees for five minutes) to kill any: microorganisms, mold (mould), fungus or spores.