cbd oil for pkd

CBD Oil Side Effects on Kidneys: What Studies Found

Chronic kidney disease (CKD) and kidney injury are two significant threats to renal function. Depending on the cause, kidney health issues can – at best – affect your quality of life and – at worst – be fatal.

Conventional treatments have existed for quite a while, and some are very effective. Unfortunately, the potential adverse effects can make those options unbearable. Naturally, some people with chronic kidney disease or kidney injury (among others) decide to look outside mainstream options.

Cannabinoid medicine exploded in recent years, with millions claiming cannabidiol (CBD) helped relieve their symptoms where prescription medication doesn’t cut it.

So how can CBD oil help with chronic kidney disease – or any renal disorder? It’s a complicated topic that, despite some research, leaves more questions than answers.

What is CBD Oil?

If you’re familiar with CBD, you likely know about CBD oil. Content and potency vary depending on the oil and brand. But at its core, CBD oil is a type of natural extract from all forms of cannabis Sativa L. – the plant species often (incorrectly) separated into “marijuana” and “hemp.”

Manufacturers extract the CBD and other compounds using methods like hydrocarbon (butane), alcohol, or CO2. Once separated, the CBD is infused into a carrier oil, like MCT, grapeseed, hemp, or coconut.

You then ingest a pre-measured amount based on your CBD dosage needs. But although many claim CBD works for symptom management, there are also CBD oil side effects to consider. We’ll get to that shortly.

How CBD is Absorbed Into the Body

CBD is absorbed into the body using a vast internal network known as the endocannabinoid system (ECS). The ECS consists of specific pathways known as the CB1 and CB2 receptors located in the central nervous and peripheral systems.

Cannabinoids like THC bind to both the CB1 and CB2, which is why recreational or medical cannabis users experience mental and physical effects.

Other cannabinoids interact with just one receptor, but CBD is one of many exceptions. Instead, cannabidiol impacts other receptors and pathways, ultimately altering the shapes of the CB1 and CB2 receptors.

This reaction affects how external (phytocannabinoids) and internal (endocannabinoids) affect the brain and body. These “adjustments” are often beneficial, as are CBD’s interactions with the serotonin, vanilloid, and other vital receptors.

But before it can do all of that, CBD needs to get into your bloodstream. There are several ways to do this. All consumption methods have advantages and disadvantages, which alter the strength, duration, and effects of CBD.

Those being treated for chronic kidney disease or (other kidney diseases) should also consider potential drug interactions.


Inhalation offers a more authentic experience for vape and joint smokers. When consumed through the lungs, CBD hits the bloodstream almost instantly. As a result, you notice effects within minutes. However, the effects wear off faster than any other method – usually within two to four hours.

Many vendors don’t offer inhalable products, often due to health concerns. We’re all aware of the vape illness epidemic that dominated the news in 2019 (and continues to this day). We also don’t know the long-term damage of inhaling burnt cannabis plant matter – although it seems safer than tobacco.


Ingestion offers a broad range of options for taking CBD. Cannabidiol extracts can be infused into hundreds of foods and drinks, from desserts smoothies – even beer and wine! A few examples are:

With ingestion, the majority of CBD is broken down in the liver. Consequently, eating or drinking CBD is the slowest-acting option. But it makes up for this by lasting up to eight hours – longer than any other method.


Topicals are another diverse group of CBD products. But unlike smoking and eating, topicals don’t enter your bloodstream. Applied directly to the skin, these products provide a more focused, instant effect.

Is CBD Oil Excreted Through the Kidneys?

We know how CBD enters the body, but how does it leave? Considering urine tests are a common way to detect drug use, you’d think the kidneys eliminate a lot of THC and CBD. But a 2019 review in the Canadian Journal of Kidney and Health Disease shows that nothing could be further from the truth.

The authors explain THC and CBD mostly exit through the feces. As a result, they feel CBD’s minor effects on kidneys don’t require a CBD dosage adjustment. However, they’re unsure if we eliminate minor cannabinoids in the same fashion.

What are the Side Effects of CBD Oil?

Studies universally found that CBD is well-tolerated with no possibility for abuse or addiction. Side effects of CBD oil are mild, especially compared to prescription medication. Still, it might not be for you. Keep an eye out for some common side effects:

  • Dry mouth
  • Appetite changes
  • Nausea
  • Fatigue
  • Insomnia
  • Dizziness
  • Diarrhea

High doses of CBD – especially when introduced immediately without titrating – are more likely to trigger those effects. If these problems persist or worsen, stop using CBD.

Since hemp oil contains little to no tetrahydrocannabinol (THC), CBD extracts shouldn’t make you high. However, if you feel intoxicated, it’s possible the manufacturer mislabeled their product.

Common Causes of Kidney Disease

According to the National Institute of Diabetes and Digestive and Kidney Diseases, chronic kidney disease (CKD) is usually caused by diabetes or high blood pressure.

However, there are many other reasons, including (but not limited to):

  • Drug interactions
  • Poison
  • Infection
  • Physical injury
  • Genetics

Symptoms of Kidney Disease

The symptoms of kidney disease can be difficult to pinpoint since various common infections or toxins often cause them. However, if you have high blood pressure or diabetes, pay extra close attention to the following signs:

  • Nausea and vomiting
  • Back pain
  • Increased or decreased urination
  • Fatigue
  • Sleep issues
  • Muscle cramps
  • Dry or itchy skin
  • Swelling of the feet or ankles
  • Chest pain
  • Shortness of breath
  • Hypertension (high blood pressure)

Regardless of the cause, chronic kidney disease is a serious threat to kidney function. If you’re concerned about your renal health, talk to a doctor as soon as possible.

Does CBD Oil Hurt Your Kidneys?

CBD oil may hurt the kidneys, but it also might help renal function. Preliminary research is either promising, inconclusive, or negative.

We’ll look at all the results next.

What Studies Say About CBD Oil Side Effects on Kidneys

The relationship between chronic kidney disease (or any other kidney health issue) and CBD oil isn’t well understood. Some research looks positive.

For example, a 2009 Study in the Journal of Pharmacology and Experimental Therapeutics discovered that CBD might help alleviate inflammation, oxidative stress, and cell destruction, reducing nephrotoxicity.

“Nephrotoxicity” refers to kidney damage from drugs or toxins. This condition makes it difficult to eliminate urine or waste, leading to a potentially deadly outcome.

The authors of the said review found that the activation of the CB1 receptors regulates renal vascular blood flow. Meanwhile, the renal CB2 receptors reduce the effects of inflammation, oxidative stress, and renal fibrosis. These findings support and explain the 2009 study’s observations.

Subsequent 2017 research in the American Journal of Physiology also concluded that cannabinoids have potentially beneficial effects on kidneys. However, they caution that we don’t know about the effects of CBD on acute kidney injury (AKI) or chronic kidney disease.

The following study shows how accurate this warning may have been.

Among the promising or inconclusive findings are some upsetting discoveries. One 2018 study in the American Society of Nephrology Found that cannabis consumers with impaired kidney function showed a faster decline than non-cannabis users.

One important detail, however, is that these subjects used THC and CBD products. This makes it difficult to determine if CBD or THC is responsible (if at all).

However, the mix of positive and negative findings might be attributed to CBD rather than CBD products. According to

2o2o review from Current Opinion in Nephrology and Hypertension says, “There is no evidence to suggest that CBD has any adverse effect on kidney function. In fact, CBD prevented cisplatin-induced nephrotoxicity in a mouse model by reducing oxidative stress. However, some products may contain toxic contaminants such as heavy metals, pesticides, and solvents.”

So are CBD’s effects on kidneys good or bad? For now, we don’t know. But even if cannabidiol is effective, quality CBD may be hard to find. Without a green light from the Food and Drug Administration, there’s no way to guarantee CBD oil is free of the aforementioned contaminants.

Potential Benefits of CBD Oil in Kidney Diseases

The effects of CBD oil on kidney disease are mostly promising but still warrant caution. But there’s some good news. Even if CBD has no direct therapeutic effects on those organs, chronic kidney disease patients can (and do) use cannabis for symptom control.

The 2020 study above mentions CBD’s potential for pain management. Researchers believe CBD may help mitigate chronic pain related to kidney disease.

They also theorize that maybe CBD’s analgesic benefits could reduce the need for opioids – but that’s an enormous “maybe.”

Dosage and Precautions for CBD Oil and Kidneys

We know very little about the effects of CBD oil on kidneys and next to nothing about the proper CBD dosage. Unfortunately, dosing cannabinoids isn’t an exact science, despite decades of research. Synthetic cannabinoids, like Sativex and Marinol, being are a couple of exceptions.

However, those prescription drugs are designed to treat specific symptoms rather than the broad range of potential benefits assigned to CBD.

It also doesn’t help that we can’t (yet) conclusively prove that CBD oil side effects on kidneys outweigh the possible beneficial effects of CBD.

But if you feel it helps with symptoms like nausea or chronic pain, you can at least benefit from those effects.

In this case, follow the “start low and go slow” rule. Begin with the smallest dose possible (usually 2.5 to 5 mg) and increase every few days as needed.

That being said, don’t try adding CBD to your daily health routine without consulting a doctor – especially if you have kidney disease.

Summary: CBD Oil Side Effects on Kidneys

There’s some promising CBD research that could be a game-changer for those with kidney injury, chronic kidney disease, or other renal function problems.

But while exciting, we need to remember Despite some worthwhile findings, none of the potential benefits have been evaluated by the Food and Drug Administration. CBD oil isn’t intended to prevent, diagnose, or treat any illness.

However, we should see these discoveries as springboards to inspire further research.


“Causes of Chronic Kidney Disease | NIDDK.” National Institute of Diabetes and Digestive and Kidney Diseases, Oct. 2016, www.niddk.nih.gov/health-information/kidney-disease/chronic-kidney-disease-ckd/causes. Accessed 25 Nov. 2021.

CDC. “Outbreak of Severe Pulmonary Disease Linked with E-Cigarette Product Use.” Centers for Disease Control and Prevention, 6 Sept. 2019, www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html. Accessed 25 Nov. 2021.

Ho, Claudia, et al. “A Review of Cannabis in Chronic Kidney Disease Symptom Management.” Canadian Journal of Kidney Health and Disease, vol. 6, Jan. 2019, p. 205435811982839, www.ncbi.nlm.nih.gov/pmc/articles/PMC6388458/, 10.1177/2054358119828391. Accessed 26 Nov. 2021.

Nesbitt, Hal. “American Society of Nephrology | Kidney Week – Abstract Details.” Www.asn-Online.org, www.asn-online.org/education/kidneyweek/2018/program-abstract.aspx?controlId=3017229. Accessed 26 Nov. 2021.

Pan, Hao, et al. “Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death.” Journal of Pharmacology and Experimental Therapeutics, vol. 328, no. 3, 12 Dec. 2008, pp. 708–714, 10.1124/jpet.108.147181. Accessed 26 Nov. 2021.

Park, Frank, et al. “Cannabinoids and the Kidney: Effects in Health and Disease.” American Journal of Physiology-Renal Physiology, vol. 313, no. 5, Nov. 2017, pp. F1124–F1132, www.ncbi.nlm.nih.gov/pmc/articles/PMC5792153/, 10.1152/ajprenal.00290.2017. Accessed 26 Nov. 2021.

Rein, Joshua L. “The Nephrologistʼs Guide to Cannabis and Cannabinoids.” Current Opinion in Nephrology and Hypertension, vol. 29, no. 2, Mar. 2020, pp. 248–257, 10.1097/mnh.0000000000000590. Accessed 26 Nov. 2021.

CBD Oil and Kidney Disease

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Over the last few years, the medical uses of cannabis have piqued the curiosity of many Americans. More states are legalizing the use of cannabis for both medical and recreational use, so medical professionals study what benefits it can have on our health.

Over 30 million Americans have some form of chronic kidney disease (CKD). The kidney’s main function is to filter blood, and kidney disease occurs when this process is impaired.

The two primary causes of kidney disease are diabetes and high blood pressure. If left untreated, these conditions can progress to end-stage kidney disease. Patients at this stage either go on dialysis or undergo a kidney transplant.

There are many different medications prescribed to patients with kidney disease. Most of them are diuretics or focus on lowering blood pressure. However, many of these medications don’t help combat the symptoms of kidney disease. They also come with side effects that make them undesirable by the patients.

So what’s the alternative?

A significant number of patients have turned to cannabidiol (CBD) to help treat the symptoms of chronic kidney disease. CBD doesn’t intoxicate its users because it doesn’t contain THC, which is the psychoactive compound found in cannabis.

If you’re looking for a natural alternative for treating kidney disease, CBD oil is worth investigating. However, there’s a lot of confusing information out there about the actual benefits of CBD oil.

This guide will cover everything you need to know about CBD oil and kidney disease.

What Causes Kidney Disease?

According to the Mayo Clinic, chronic kidney disease occurs when kidney functions gradually deteriorate.

The main job of the kidneys is to filter waste and other unnecessary compounds from the blood. Without our kidneys, toxins would overwhelm our blood and ultimately damage other organs, causing our bodies to shut down.

Early signs of kidney disease are often difficult to detect without a proper examination. Unfortunately, many patients don’t notice they have chronic kidney disease until there has already been noteworthy damage.

Here are some of the common causes of chronic kidney disease:

  • Diabetes (both type 1 & type 2) – Diabetes is when blood glucose levels are higher than normal. Excess glucose can damage blood vessels, which makes them inefficient. As a result, diabetes usually leads to high blood pressure, which can ultimately damage the kidneys, causing kidney disease.
  • High blood pressure – High blood pressure (hypertension) is the number one cause of kidney disease. It can directly damage the filters (the glomeruli) within the kidneys, causing them to malfunction.
  • Glomerulonephritis – Glomeruli are important components of the kidneys. Glomerulonephritis is when the blood vessels within the glomeruli—the kidney’s filtration units—become inflamed or damaged. This damage can lead to chronic kidney disease.
  • Interstitial nephritis – Interstitial nephritis is inflammation around the tubules within the kidney. This inflammation impairs the ability of the kidney to filter waste properly.
  • Polycystic kidney disease – PKD Is a genetic disorder that causes multiple cysts to form within the kidney. The cysts contain fluid, and can grow large enough to interfere with kidney function.
  • Vesicoureteral reflux – In this condition, urine backs up in the kidney tract, leading to inflammation, urinary tract infections, and scarring that can destroy kidney function.

There are many causes of kidney failure, but the two main causes are diabetes and hypertension. The best way to know if you are experiencing kidney disease is to consult your doctor for a thorough examination.

Introducing CBD Oil

CBD oil has skyrocketed in popularity over the last few years. It’s known as a healthy natural alternative to most over-the-counter medicines, and can also treat unpleasant symptoms such as chronic pain, stress, anxiety, and insomnia. But what exactly is CBD oil, and how does it work?

CBD is short for cannabidiol, which is a compound found in the cannabis plant. So, in short, CBD comes from marijuana and hemp. Though CBD comes from marijuana, it doesn’t get you high. CBD a great alternative for those who want to experience the medical benefits of cannabis without THC.

CBD is extracted from hemp plants using carbon dioxide or other methods. After extraction, it’s refined and prepared to be used by the consumer by mixing with a carrier oil that helps to deliver and preserve the extracted CBD. You can purchase CBD either online or in most stores that sell dietary supplements. It’s important only to consume CBD that was extracted safely by a reputable manufacturer.

Now that marijuana is becoming more acceptable in the United States, researchers and medical professionals are starting to recognize CBD as the main therapeutic compound found in cannabis. It’s a versatile substance that comes in many different shapes and forms.

More research is underway on the direct effects CBD has on the body and how it can treat certain symptoms, but CBD oil is already a recommended treatment for several conditions.

When CBD oil enters the body, it reacts with receptors in the endocannabinoid system (ECS), which help regulate pain, sleep, inflammation, and other effects regulated by the nervous system. When ingested through the digestive system, these effects seem amplified. That is why ingesting CBD oil in the form of food or tablets is so popular.

Since the widespread use of CBD oil is relatively new, the exact reasons for its positive effects on the body are still unknown. More research is underway to narrow down how exactly it works in the body and whether it’s a viable long-term solution. Currently, CBD oil should only be used as a supplement to known kidney disease treatments, not as a cure.

There has been some promising research done on CBD oil and kidney disease. While no research has been able to solidify a connection between CBD and kidney receptors, patients have experienced less severe symptoms while taking the natural herbal remedy. CBD has also been proven less harmful to the kidneys than other common drugs such as ibuprofen and aspirin.

How Does CBD Oil Help With Kidney Disease?

Kidney disease is one of the major killers in the United States. It’s deadlier than both breast and prostate cancer. The most alarming aspect of chronic kidney disease is that it’s often undetected until it has already caused significant damage. Some symptoms of kidney disease are low energy, bloody urine, unnatural weight loss, and difficulty breathing.

Due to the developing research on CBD oil and kidney disease, many patients seek out the herbal remedy as a form of treatment. CBD oil is widely known to help treat symptoms such as pain and inflammation, both of which are omnipresent in patients diagnosed with chronic kidney disease. Therefore, if you’re experiencing pain due to chronic kidney disease, CBD oil may help.

Cannabidiol amplifies what our bodies do naturally. As mentioned above, our bodies already have an endocannabinoid mechanism that binds CBD compounds. It primarily works as a neurotransmitter, which signals your brain to alleviate pain and promote relaxation. Naturally, the body might produce endocannabinoids as a mental defense to an injury or a stressful situation.

CBD oil can help relieve pain and anxiety and let your body’s internal systems zero in on the more crucial steps toward recovery. When CBD binds with your cannabinoid receptors, it allows the tissue around the kidney to produce more anandamide, blocking pain. Other compounds found in cannabis such as THC also aid in this process, but CBD specifically does the best job.

To better understand how CBD oil helps treat chronic kidney disease symptoms, let’s first break down different pain receptors. Here is a not-too-technical crash course on how receptors work.

Receptors 101: What are they?

Your brain is a network that transmits and receives information throughout the body. Signals get sent through the nervous system, which is just a complex system made up of billions of cells. Imagine the brain as the control center for the body’s functions and pain receptors as different lookout towers stationed throughout the body.

Whenever there’s damage to organ tissue, such as the kidney, pain receptors send a signal to the brain to initiate a defense. Neurotransmitters like endocannabinoids can regulate these signals, causing them to be less severe. In other words, they make you feel less pain.

The two key receptors for CBD oil are:

CB1 Receptors – Receptors found in the spinal cord, and the brain
CB2 Receptors – Receptors located throughout the body.

It’s no surprise then that many people are looking into CBD oil as a treatment for chronic kidney disease. It’s non-toxic and has fewer long-term effects (if any) on the body compared to other forms of medication.

There are also other benefits of taking CBD oil other than treating CKD. It can also help improve your sleep cycle, decrease anxiety, increase your appetite, and decrease joint inflammation.

Other Benefits of CBD Oil

Research has shown that CBD oil may be a suitable treatment for those with chronic kidney disease. CKD comes with a multitude of symptoms that cause fatigue and discomfort. CBD oil can help combat the symptoms of CKD, allowing patients to be in a more relaxed state as they battle the disease.

Here are some of the additional benefits of taking CBD Oil:

    – Battling a disease such as CKD can take a huge toll on your mental health, adding additional stress and fatigue, which is not ideal for a healthy recovery. Studies have shown CBD oil to reduce anxiety and depression in most users. – There’s no doubt that the symptoms of CKD can be painful. CBD oil can amplify your body’s natural response to pain. It won’t eliminate the pain, but it’s a much healthier alternative to most pain medications. – When humans are sick, we tend to lose our appetite. Decreased food intake is detrimental because our bodies need food’s energy to recover. CBD oil might increase appetite in certain users. However, there hasn’t been enough research to support this claim. – Insomnia can result from a variety of factors such as anxiety, caffeine consumption, and medications. CBD oil can help treat the main causes of insomnia, improving sleep quality.

Does CBD Oil Have Any Negative Side Effects?

Before undergoing a new form of treatment, it’s important to know that it’s both safe and effective. Modern medicine has blessed us with a wide variety of choices. However, some remedies can do more harm than good. Luckily CBD oil is labeled safe by most medical professionals if it’s extracted safely and consumed responsibly.

Just like any other treatment, CBD oil has guidelines for safe consumption. You have to know the right dose and frequency to take. Though it’s not a deadly substance, there are a few negative side effects of misuse, including:

  • Dry mouth
  • Upset stomach/diarrhea
  • Increased heart rate
  • Groggy headaches
  • Nausea/dizziness
  • Changes in appetite

Taking CBD oil can also offset the effects of other medications. If you’re currently taking medication for CKD, make sure to consult your doctor before trying CBD oil. As mentioned above, CBD oil should be handled as a supplemental treatment, not as a magical cure.

You must purchase your CBD oil from a reputable brand. Since the substance is in such high demand, many “enthusiasts” create homemade oil and sell their products online. Unless you’re sure the CBD oil was extracted in a controlled environment and lab-tested, you should hesitate to buy it.

The negative effects of CBD aren’t severe and often go unnoticed. Compared to other medications that have numerous negative side effects, it’s no surprise that CBD oil is more desirable. However, make sure you consult a healthcare professional to see if you’re suitable for CBD treatment before searching for products.

How to Take CBD Oil

For starters, before you use CBD oil to help treat chronic kidney disease, you need to ask your doctor or check the packaging to determine the correct dosage. Most reputable manufacturers will have dosage guidelines for you to follow. You’ll need to gradually increase your dosage over time to feel the same effects.

CBD oil is a versatile product. There are many ways to consume CBD oil, and that is why it’s so popular. Each method has its unique benefits—it’s all about finding the form most comfortable for you.

Here are some of the most common ways to consume CBD oil:

Edibles – If you’ve been to a health supplement store recently, you may have noticed CBD gummies, cookies, or even lollipops. Edible CBD products, as you may have guessed, are eaten by the user. Though CBD is becoming more accepted across the country, edibles are a less obvious way of using CBD than smoking it.

Be careful when eating CBD edibles, though. They can take up to two hours to kick in. Some people unknowingly eat too much at once and can start to feel sick.

Tinctures and oil– This is by far the most common way to consume CBD oil directly. CBD is mixed with a carrier oil or a small amount of alcohol for absorption through the skin (typically under the tongue). This form is one of the fastest ways to feel the effects of CBD oil.

Topical creams – Did you know that CBD oil can also be a beauty product? You can find many lotions and balms that contain CBD oil, which is applied directly to the skin. In this, “two birds, one stone” scenario, CBD oil can soothe skin and provide medical benefits.

Smoking – Smoking isn’t the healthiest way to consume CBD, but if you already smoke, this might be a suitable method. You can get CBD in the form of flowers and smoke it in a joint, blunt, pipe, or even vaporize it.

Many companies make vape cartridges that contain CBD oil. Vaping is one of the most convenient ways to consume CBD oil. However, THC-containing e-cigarettes have been implicated, but not positively associated with, lung damage in users. The effects might be due to contaminants, carriers, or oils in the vaping solution, and it’s not clear if CBD vaping carries the same potential risk.


Every day, research is discovering more health benefits from CBD oil. For patients experiencing chronic kidney disease, CBD oil can be a healthier alternative to over-the-counter medications. Also, it’s a great way for patients to reap the benefits of cannabis without ingesting THC.

Remember to make sure you’re getting your CBD oil from a trusted source. The best way to know whether or not a manufacturer is reliable is to check their reviews online. Most companies selling high-quality CBD products have a long list of positive reviews from customers.

Another way to determine a company’s credibility is to see how good their customer service is. Good customer service is normally a by-product of a high-quality brand.

Now you have the confidence to start looking into CBD oil as a supplement to treat some of the symptoms of chronic kidney disease.

FAQs About CBD Oil and Kidney Disease

Question: Can you use CBD to help treat kidney disease?
Answer: A significant number of patients have turned to cannabidiol (CBD) to help treat the symptoms of chronic kidney disease. CBD doesn’t intoxicate its users because it doesn’t contain THC, which is the psychoactive compound found in cannabis.

Question: How does CBD work?
Answer: When CBD oil enters the body, it reacts with receptors in the endocannabinoid system (ECS), which help regulate pain, sleep, inflammation, and other effects regulated by the nervous system. When ingested through the digestive system, these effects seem amplified.

Question: How Does CBD Oil Help With Kidney Disease?
Answer: Due to the developing research on CBD oil and kidney disease, many patients seek out the herbal remedy as a form of treatment. CBD oil is widely known to help treat symptoms such as pain and inflammation, both of which are omnipresent in patients diagnosed with chronic kidney disease.

Question: What are the two key receptors in CBD oil?
Answer: CB1 Receptors. Receptors found in the spinal cord, and the brain. Another one is the CB2 Receptors. Receptors located throughout the body.

Question: What are the other benefits you can get in CBD oil besides helping in kidney disease?
Answer: CBD can help anxiety & depression, pain relief, regulate appetite, and can give you a good sleep.

Question: Does CBD Oil Have Any Negative Side Effects?
Answer: Some of the negative side effects of CBD oil includes dry mouth, diarrhea, increased heart rate, headaches.

Question: How do you take CBD oil?
Answer: Some of the common ways to take CBD is through tinctures, topical creams, edibles or gummies, smoking, and supplements.

CBD Oil for Kidney Disease: Benefits, Side Effects, and Dosage

CBD may provide support for kidney disease through its anti-inflammatory, antioxidant, and analgesic benefits.

But there are some limitations to be aware of.

Here’s how you can get started using CBD oil today.

Article By

According to research conducted by the American Kidney Fund, roughly 10% of the American public are believed to suffer from chronic kidney disease.

In this article, we’ll explore how to use CBD as a supplement for chronic kidney disease, how it works, and when you should avoid it.

Let’s get straight into it.


Updated on January 12, 2022

Table of Contents
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Summary: Using CBD for Kidney Disease

Cannabis could be a useful aid in managing certain symptoms of kidney disease — which often includes chronic pain, nausea, emesis, anemia, itching, insomnia, and an overall lack of well-being

There’s evidence that CBD and other related cannabinoids can support the health of the kidneys during both acute and chronic kidney disease in mice — though this has yet to be confirmed with research on humans.

One of the main advantages of using CBD over other pain medications is that it doesn’t cause any additional damage to the kidneys.

Other pain medications — such as acetaminophen or opiate medications — are metabolized by the liver and eliminated through the kidneys. These drugs have been shown to cause damage to the sensitive cells making up the kidneys, which can lead to a worsening of the condition.

CBD is also metabolized by the liver but has been proven not to cause additional damage to the kidneys — making it a non-toxic option for managing kidney-related pain.

The Benefits of CBD for Kidney Disease:
  1. Potentially reduces pain associated with common side-effects of kidney disease
  2. May slow the progression of kidney disease
  3. Studies suggest it may lower inflammation of the kidneys
  4. Could help protect the kidneys from oxidative damage

What’s the Dose of CBD Oil?

Kidney disease is a severe disease so any potential treatment options should be discussed with a medical doctor. This condition can quickly lead to serious consequences.

With that said, many people with kidney disease are turning to CBD as an adjunctive treatment option along with other medications and diet/lifestyle modifications.

Finding the right dose of CBD can be a challenge, as the compound affects everybody differently.

Unfortunately, there isn’t much research highlighting the effective dose of CBD for kidney disease — most of the research done up to this point has been investigating the safety of using CBD with kidney disease (which is positive) and animal testing to explore how it works.

We can use dosage information from similar conditions, such as liver or cardiovascular disease which involve similar mechanisms of action. Usually, these conditions require higher doses of CBD to produce effects.

Therefore, it’s likely that the dose of CBD should be on the higher end of the spectrum to be useful for kidney disease.

Whenever using CBD (or any supplement for that matter) for the first time, it’s essential that you start with a small dose, and build up gradually over time once you know how it affects you individually.

We recommend starting at the low-strength dose and build up slowly over time to the medium or high-strength doses.

Calculating CBD Dosage Strengths By Weight

Unit of Measure Low Strength Medium Strength High Strength
Imperial (pounds) 1 mg every 10 lbs 3 mg every 10 lbs 6 mg every 10 lbs
Metric (kilograms) 1 mg every 4.5 kg 3 mg every 4.5 kg 6 mg every 4.5 kg

Using this information, you can calculate what a low dose, medium dose, or high dose of CBD may look like.

To simplify this for you, we’ve included a dosing chart based on weight and desired strengths.