cbd oil for ptsd and anxiety

5 Best CBD Oils for PTSD | Exploring the Options

Life is full of unexpected and difficult circumstances. Sometimes after a traumatic life event, memories of the situation persist in the form of a disorder known as PTSD.

PTSD is typically thought of as being prevalent among veterans who witnessed gruesome events during deployment. However, plenty of other people can also experience symptoms.

Children who have been abused, for example, often experience PTSD. Rape victims, police officers, and firefighters also frequently experience PTSD after traumatizing circumstances.

It goes without saying that PTSD makes life challenging – sometimes even debilitating. It can cause isolation not only from yourself, but also from people around you. Loved ones, friends, and family members are all affected.

What Triggers PTSD?

PTSD arises when an individual becomes triggered. Triggers can stem from anything and can arise at any moment in time. This is why PTSD is so unexpected and unpredictable.

Although there are treatment methods for PTSD, many are seeking alternative therapy in the form of CBD. Though clinical studies are lacking, we do know that CBD oil can help some people who suffer from PTSD.

In this article, we’ll take a close look at using CBD oil for PTSD. In addition to including a few firsthand stories of how CBD oil has helped people with PTSD, we have provided a basic jumping off point in terms of what CBD products to trust. Moreover, we have also highlighted key research studies on the success of CBD oil, as well as frequently asked questions regarding how to use the all-natural extract.

Keep reading to discover the 5 Best CBD Oils for PTSD…

PTSD and the Benefits of CBD Oil

The way in which CBD oil helps individuals with PTSD is fairly unique. The compound directly targets chemical responses that produce stress, anxiety, depression, and many of the other mental symptoms associated with PTSD. Triggers will still exist in everyday life, but by reducing these symptoms, CBD can help to block the mood receptors that are triggered, thereby:

  • Promoting natural sleep hormones
  • Regulating stress hormones
  • Blocking reconsolidation memory (flashbacks, etc.)
  • Improving extinction learning (which is the reprogramming of the brain’s response in certain circumstances)
Real Accounts of Using CBD for PTSD

In fact, most everything CBD does relates to mechanisms that individuals with PTSD must experience in order to relieve and reduce the onset of symptoms. Here are two firsthand accounts of instances where CBD use has helped victims of severe post-traumatic stress disorder:

“I served in the military for 2 years, and came back home from my deployment with a serious case of diagnosed PTSD. Although I speak with a therapist regularly, I also manage my PTSD by taking 30 mg daily doses of pure CBD oil. This incredible element helps me sleep better, in addition to decreasing my day to day sensitivities to outside triggers. CBD oil has made a profound difference in not only my life, but also the lives of my family surrounding me and my friends.”

“5 years ago I survived a tragic car accident. Although the physical damage to my body has pretty much all healed, my mind was overwhelmingly damaged by the incident. I was diagnosed with PTSD a couple years ago, and searched high and low for something to relieve the constant anxiety and panic I was experiencing, sometimes from simple and normal outside triggers. I started ingesting CBD oil about 9 months ago, and the results have been astonishing. Now, I am able to drive my car to work and back without experiencing panic attacks, and my general overall sensitivities in day to day life have improved.”

Frequently Asked Questions: CBD Oil, PTSD, and Therapeutic Effects

Aside from personal accounts of PTSD patients who have discovered success with the help of CBD, thousands of other individuals have had similar experiences. Simply put, the seemingly miraculous healing benefits of CBD oil are not going unnoticed.

PureKana , one of the US’ most reputable CBD oil producers, has gone so far as to receive praise from media outlets and popular magazines, and CBD as a whole has been featured on many popular sites such as Men’s Health, The Wall Street Journal, and CNN.

Here are a few frequently asked questions about what CBD is, how it’s used, and how it has been incorporated into reliable treatment for symptoms of PTSD.

What Are Some of the Benefits of CBD?

There are so many benefits of CBD, the list would go on forever if we mentioned them all. However, here are just a few examples to begin with:

  • Anxiety
  • Arthritis
  • Chronic pain
  • Depression
  • Inflammation from various conditions
  • Insomnia
  • Multiple Sclerosis
  • Nausea (emesis)
  • Obesity
  • Post-Traumatic Stress Disorder (PTSD)
How Is CBD Oil Extracted?

There are a few various ways to get the CBD out of the marijuana or hemp plant, but the purest method that creates the best quality final product, is known as CO2 extraction . During this method, high pressure carbon dioxide is applied at very low temperatures, and this process requires an immense level of experience and professionalism to successfully, safely accomplish, as well as expensive, qualified machinery, so not everyone can make oil in this manner.

Is CBD Legal?

Most manufacturers claim that CBD from industrial hemp is legal in all 50 states, as long as THC amounts are under 0.3%. These products are delivered to any doorstep, anywhere within the United States. Products with THC amounts higher than 0.3% are legal in some states , so be sure to do some research and familiarize yourself with what’s legal – and what’s not – in the area you live.

How Long Does It Take the Body to React to the CBD?

This of course greatly depends on a person to person basis, but typically speaking it takes around 20-40 minutes for CBD to kick in. Because these products do not contain any THC, you won’t experience any psychoactive or “high” effects.

5 Best CBD Oils for PTSD

1. PureKana

One of our all time favorite vendors, and rated as one of the top CBD oil producers of 2017, PureKana is our go-to recommendation for those just getting started with this medicinal, all-natural alternative to pharmaceuticals. Their products are of the purest quality, and are produced using the most advanced CO2 extraction methods. Their customer service is also superior, and they offer quick, efficient shipping and delivery services to customers throughout the U.S.

[Receive 20% off your next order today, just by using our discount code: 20KANA ]

PureKana CBD products are:
  • Tested by third party labs for purity and quality
  • 100% organic and non-GMO
  • Delivered to all 50 states in the U.S.
  • Non-psychoactive
  • Lab-tested to produce 99% product purity

To view the full range of PureKana CBD products, visit their site at www.purekana.com

2. PremiumJane

Offering one of the best quality products in the industry, PremiumJane displays an attractive collection of both CBD oils and edibles. The company has really put a lot of effort into creating a solid product that not only tastes good but is also effective. One thing we love about PremiumJane is that they assure quality and professionalism from the source of the product, until the moment when it is delivered at your doorstep.

Features of Premium Jane CBD oils:
  • Potent CBD products available, offering variety and a multitude of options for all individual types and needs
  • Affordable prices, ranging from $48.00-$124.00

Need more details about Premium Jane? Visit their online store at premiumjane.com

3. Elixinol

World-renowned CBD vendor Elixinol not only offers top quality products, but also displays information with clarity and ease and offers solutions and suggestions for those who might feel lost during their hunt for the right CBD selection. As mentioned earlier, Elixinol has received media recognition from multiple sources, so their hard work and attention to service and detail is not going unnoticed.

Elixinol CBD oil highlights:
  • Massive variety of products
  • Product prices ranging from $39.00-$249.00
  • Mild, moderate and strong formulations are available

Want to learn more about Elixinol’s products? Head on over to www.elixinol.com [And don’t forget to use our coupon code 10off591 if you’re thinking of picking up a bottle!]

4. CBD Essence

CBD Essence offers a diverse collection of products ranging from gels, creams, gummies, powders, pet-safe products and tinctures. This is a brand that masterfully knows how to develop pure and honest CBD products, which can be used by a variety of individuals.

CBD Essence highlights:
  • Certified safe for humans and pets
  • EU Industrial grade certified hemp products
  • Delivery straight to your doorstep in all 50 states

Want to learn more about CBD Essence? Visit their expansive online store at www.cbdessence.com

5. CBDPure

CBDPure utilizes a rather unique company model in which their focus is upon 3 core products, ranging in a variety of potency levels. By focusing on such a small range of products, the company is able to produce and specialize on a smaller, yet brilliantly-developed selection so that all of their listings go above and beyond in standards.

CBDPure employs transparent and honest communication with customers, clients, and other vendors, as well as offers helpful information and advice to those who are trying to choose the right path towards healing with CBD.

CBDPure Highlights:
  • All products produced from Danish industrial-grade certified hemp
  • 100% free from synthetic and artificial ingredients free
  • Certified non-psychoactive
  • Products extracted with CO2 methods
  • 90-day satisfaction guaranteed (CBDPure wants to work with you, not against you!)

Want to learn more about this super brand, read the complete CBDPure Review

CBD Oil, PTSD, and Where to Start

Although the internet is full of options to choose from, one easy place to start your CBD journey would be with the trustworthy company PureKana . After surveying, testing, and reviewing numerous oils and CBD products from a multitude of companies, it is clear to us PureKana offers the best overall value — especially if you are a beginner to the world of hemp-derived products.

Their website is easy to navigate, and they offer detailed information about each product. Furthermore, their customer service is world class, and they even can assist you in discovering a product that is right for you. What’s even better is the fact that their selections are all certified organic and verified non-GMO, so the quality and purity is top-notch.

Final Thoughts About CBD Oil for PTSD

Most of the products listed above are risk-free, making them simple and convenient to try – especially if you or a loved one is suffering from the debilitating effects that PTSD can have on your life.

Pharmaceutical and conventional medications still have a difficult time controlling the symptoms of PTSD, but surprisingly, CBD oil has experienced success in several instances where conventional drugs have not.

CBD can be coupled with traditional talk therapy as a brilliant combination for relief, though it is important to keep in mind that none of the information above is clinically proven, and thus should not be interpreted as medical advice.

Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder

The overarching objective of the proposed project is to test the clinical efficacy of CBD in the treatment of post-traumatic stress disorder using a rigorous double-blind randomized clinical trial methodology. Participants (n=150) meeting full DSM-5 criteria for post-traumatic stress disorder (PTSD) will be randomized to one of 3 treatment arms: (a) CBD -Isolate; (b) CBD-Broad Spectrum; (c) Placebo oil.

We predict that patients receiving CBD isolate or CBD Broad Spectrum will show significantly greater improvements in PTSD symptoms and functional impairment at the posttreatment, one month, and three month follow-up assessments relative to patients receiving placebo oil. Additionally, we expect that patients receiving CBD Broad Spectrum will show significantly greater improvements relative to patients receiving CBD Isolate.

Condition or disease Intervention/treatment Phase
Post Traumatic Stress Disorder Drug: CBD Isolate Other: CBD Broad Spectrum Other: Placebo oil Phase 2

Background and Significance of the Proposed Project

Over 80% of Americans are exposed to a significant trauma sometime during their lifetime and approximately 7% will meet for a threshold diagnosis of posttraumatic stress disorder. PTSD is the most costly anxiety-related disorder and confers significant interference in work, social functioning, increased risk for other physical and mental health problems, and a four-fold increase in suicide rates compared to the general population.

Over the past two decades, trauma-focused psychotherapies for PTSD have been shown to outperform more traditional supportive psychotherapy or pharmacotherapy and have become the first line treatment for PTSD. Despite these advances, trauma focused treatments such as prolonged exposure therapy (PE) are associated with high rates of treatment refusal, and among those who do enter treatment, approximately 25% drop-out. These data highlight the need to develop PTSD treatment strategies that are both effective and more palatable to patients.

More recently, there’s been considerable excitement in the press over the potential therapeutic use of cannabidiol (CBD) products in the treatment of a variety of physical and mental health problems.( Delta-9-tetrahydrocannabinol (delta-9 THC) is still illegal in most states because of its psychoactive abuse potential. In contrast, cannabidiol (CBD) does not convert to THC in the body and has negligible side effects relative to main stream psychiatric drugs (benzodiazepines and antidepressants) commonly prescribed for the treatment of PTSD. Mounting evidence from studies with rodents suggests that CBD may confer significant promising health-related benefits including anti-inflammatory, pain-relieving, anti-cancer, memory enhancement, and facilitation of fear extinction (see White for a recent review).

The biggest success story for CBD use in humans to date comes from controlled randomized clinical trials demonstrating a 50% or more reduction in previously intractable seizures in children suffering from Dravet syndrome and Lennox-Gastaut syndrome. Moreover, several controlled clinical trials have shown promising findings in reducing psychotic symptoms among patients with schizophrenia and among young adults displaying THC-induced psychosis.

Preliminary Evidence that CBD may offer promise in the treatment of anxiety-related disorders has started to emerge. A small pilot trial with 24 patients presenting with social anxiety disorder found that relative to placebo, a single dose of 100 mg of CBD oil led to lower levels of anxiety, cognitive impairment, and discomfort in their actual speech performance as well as their anxiety before the speech. Unfortunately, human treatment studies for anxiety-related problems is limited almost exclusively to single dose effects on an anxiety challenge task. Studies are clearly needed to assess the effects of multi-dose CBD treatments across the full spectrum of trauma and anxiety-related disorders such as posttraumatic stress disorder.

The overarching objective of the proposed project is to test the clinical efficacy of CBD in the treatment of posttraumatic stress disorder using a rigorous double-blind randomized clinical trial methodology.

Specific aims of the project include:

Compare the efficacy of an 8-week multi-dose regimen of two CBD oil formulations (CBD Isolate (300 mg/day) and CBD Broad Spectrum) relative to placebo oil in reducing clinician and patient-rated PTSD symptoms at the posttreatment and one month follow-up assessments.

We predict that patients receiving CBD oil (CBD isolate or CBD Broad Spectrum) will show significantly greater improvement in PTSD symptoms and functional impairment at post-treatment and one month follow-up relative to patients receiving placebo oil.

We also predict that patients receiving the CBD Broad Spectrum formulation will show significantly greater improvement in PTSD symptoms and functional impairment relative to patients receiving CBD Isolate.

Examine predictors of patients’ clinical response to the various treatment combinations.

We expect that the superiority of CBD relative to placebo will be more pronounced for patients showing more severe PTSD symptoms at baseline and for those showing significant sleeping difficulties.

We expect that CBD-treated patients will show equivalent levels of side effects as those receiving placebo oil.

STUDY METHODS AND PROCEDURES

Participant Recruitment: 150 participants between the ages of 18 and older will be recruited through several outlets including notices posted on campus, announcements on our research laboratory website and national organizations related to PTSD and its treatment.

Participant Screening: Participants will undergo a two-stage screening procedure. Stage 1 will be a brief structured web-based screening interview. Stage 2 will be a telephone-administered structured clinical interview (CAPS-5). Participants meeting the following inclusion and exclusion enrollment criteria will be invited to take part in the study (see below).

NOTE: ALL STUDY PROCEDURES ARE COMPLETED AT PARTICIPANTS’ HOMES. NO VISITS TO OUR RESEARCH LABORATORY ARE REQUIRED.

  1. Meets for a current DSM-5 diagnosis of PTSD as their "primary" mental disorder
  2. Age between 18 to 70
  3. Fluent in English
  4. Willingness to provide signed informed consent online
  5. No history of a suicide attempt in the past 6 months
  6. No history of psychosis with the past 6 months

9. No history of current alcohol or substance use disorder within the past 6 months.

10. No current medical problems that would preclude safe ingestion of CBD oil 11. Willingness to refrain from other forms of Cannabis use during the 8-week treatment phase of the study.

12. Has home access to the internet.

Participant Informed Consent:

All study participants will be consented by the study coordinator or a doctoral student research assistant during the screening visit conducted over the phone. The online informed consent document will provide participants with information regarding the aims of the project, what they will be asked to do, any anticipated risks or benefits associated with participating in the study, as well as a clear statement that their participation is voluntary and that they may discontinue participation at any time.

Study Design Overview: The research plan is to conduct a Phase II double-blind placebo controlled randomized clinical trial comparing the efficacy of two CBD oil (300 mg./day) versus Placebo Oil.

Nightly dosing of a hemp-derived formulation of purified CBD isolate (300 mg), CBD Broad Spectrum (300 mg.) or matching placebo oil daily for 8 weeks. Individual doses of both CBD formulations and placebo oil will be provided in identical individual plastic syringes. All patients, PI, and staff who interact with study participants will be blind to participants’ assigned treatment condition.

Clinical Assessment Schedule:

Week 0 – Pre-Treatment Screening Visit: All enrolled study participants will complete from their home a clinical assessment battery consisting of (a) self-report rating scales over the Internet (see measures); and (b) a structured clinical interview (CAPS-5).

Treatment Visits (Weeks 1 – 8) : During this phase, all study participants will (a) receive via Fed-Ex their weekly allotment of CBD/Placebo oil; (b) complete weekly clinical status assessments via the Internet (see measures).

Posttreatment Assessment Visit (Week 9): All participants will complete an online battery of clinical outcome measures identical to those administered during their pre-treatment visit (see outcome measures).

1-Month Follow-up Assessment Visit (Week 13) – All participants will be re-administered the complete battery of primary and secondary outcome measures (see outcome measures).

Primary Clinical Outcomes: The primary clinical outcomes will be (a) scores on the Clinician Administered PTSD Scale (CAPS-5) and (b) independent evaluator ratings of clinical status using the Clinical Global Improvement Scale administered at each of the three posttreatment assessment periods (Week 9, Week 13).

Secondary Clinical Outcomes: Several additional psychiatric outcomes will be assessed at each of the three follow-up assessment visits. These clinical outcomes and their respective measures appear below. Additional information on these measures is available in the accompanying cited publication for each measure.

  • Patient-rated PTSD symptoms using the PCL-5
  • Depression – Patient Health Questionnaire (PHQ-9)
  • Life Impairment – Sheehan Disability Scale (SDS)
  • Quality of Life – World Health Organization (WHOQOL-BREF)
  • Substance Use Disorders – NIDA-Modified Alcohol, Smoking, and Substance Involvement Screening Test (NIDA M-ASSIST)
  • Pittsburgh Sleep Quality Index (PSQI)

Data Management Data Management involves development of methods for ensuring that data collection instruments are programmed; data are properly collected; participants are tracked and monitored over the course of the study; data sets are documented and maintained; variables are created and documented; and main analyses are conducted. To enhance quality control, all data for the current study including demographic information, diagnoses, and participant and clinician rated measures will be directly entered into a HIPPA compliant electronic case report form (eCRF) using Qualtrics – a secure cloud-based platform designed exclusively for supporting HIPPA compliant data capture and storage. Qualtrics provides: (a) An intuitive interface for data entry with data validation; (b) Audit trails for tracking data manipulation and export procedures; (c) Procedures for importing data from external sources; (d) Automated export procedures for seamless data downloads to common statistical packages (SPSS, SAS, Stata, R) to facilitate data analysis; (e) automated and secure data back-up and storage to servers housed at the University of Texas Population Research Center (PRC). Dr. Telch in his role as Principal Investigator will serve as the Senior data manager and will meet bi-weekly with the biostatistician and research staff on issues related to data management.