cbd oil with mct for dementia

CBD for Dementia

Dementia is not a single disease; it’s an umbrella term for memory loss, which interferes with day-to-day lives. It affects language, problem-solving, and critical thinking abilities. Among all the brain disorders, Alzheimer’s is the most common category of dementia. Though treatments can help, dementia is incurable.

There’s no hard evidence proving that cannabidiol can stop or prevent the progression of dementia, but it has shown effective results in improving behavioral conditions, including aggression, mood swings, irritation, and more. CBD is garnering a huge reputation in the medical field due to its therapeutic and healing properties. But can CBD for dementia be an effective treatment? Let’s find out!

8 Best CBD for Dementia in 2022

View all CBD oil for Dementia

CBD in a Nutshell

Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the two prime components found in hemp plants. Unlike THC, CBD doesn’t affect the mind because it contains zero psychoactive compounds. Instead, studies suggested that CBD can be used for medicinal and recreational purposes due to its restorative properties. Besides extracted from the marijuana plant, cannabidiol is safely sourced from organic hemp plants, which are industrially grown. The products are lab tested, and thus are made legal in many states.

What’s Dementia?

Dementia is characterized by a group of conditions, including Parkinson’s, Alzheimer’s, Lewy body dementia, vascular dementia, and frontotemporal dementia. The abnormal changes in the brain cells cause a decline in cognitive abilities, weakening memories, and other cerebral functions. This also triggers a change in thinking, explaining, and judgments. Dementia affects feelings, relationships with people, and impedes daily life functions.

In the maximum of the cases, 60-80% of people are reported to suffer from Alzheimer’s. Besides this, vascular dementia is the second most found cases, and it is caused due to blockage in blood vessels and microscopic bleeding in the brain.

What are the Dementia Symptoms?

The warning signs of dementia include:

  • Fails to keep track of personal items;
  • Problems with short-term memory;
  • Problems with counting;
  • Preparing and planning meals;
  • Going out in the neighborhood;
  • Failing to remember appointments.

The signs start very slowly and with time get worse. Early diagnosis can help in controlling the progression, but there’s no possible cure. Now, many studies suggest that CBD hemp oil for dementia can help in improving the condition and symptoms related to it.

How CBD Works for Dementia?

Weed-infused products improve dementia-related conditions as the cannabinoids recover the connection between the brain cells. There’re three ways in which CBD oil for dementia can improve the condition:

  • By reducing inflammation within the membranes;
  • By lowering the buildup of oxygen;
  • By functioning as a neuroprotectant and brain stimulant.

Since CBD reduces anxiety and stress, it works great with dementia patients. It helps them in stabilizing moods and enhancing other brain functions. Want to know more? Check our review sections.

CBD for Alzheimer

In current studies, it has been concluded that CBD removes swelling and oxygen buildup from the brain and stop the declining activity in the brain cells. In Alzheimer’s, inflammation occurs when the immune cells in the brain fail to clear the blockages. The key cause of Alzheimer’s is swelling that can be controlled using CBD products.

When the brain cells swell up, more oxygen is released, causing a drop in cerebral functions. With more inflammation, you will face more negative impacts. Loss of memory and other weakening of functions are directly linked to the increased oxygen in the brain. As CBD contains antioxidant properties, it lowers the stress in the brain and stimulates the tissues.

CBD has shown unbelievable results in clinical trials, proving to have the ability to reverse and stop the negative impact on the brain. It promotes the growth of brain cells, thus, recovering patients from short-term memory loss.

CBD For Vascular Dementia

In vascular dementia, patients have problems in aligning different thought processes like, planning, reasoning, memories, and judgment. This is caused due to the restriction of blood flow to the brain. A study has found that medical marijuana for dementia activates CB2 receptors in the brain, boosting the flow of blood. When CB2 receptors get triggered, the activity in the brain cells increases, hence, reducing the damage.

If you’re looking for medical weed, you can check our top 8 product list

CBD for Lewy Body Dementia

Lewy body dementia is a condition in which alpha-synuclein, a kind of protein that gets deposited in the brain. These deposits, often termed as Lewy bodies, affect chemicals present in the brain, hindering mood, sleep, behavior, and movement. The interesting fact about CBD is that it doesn’t block acetylcholine, the active component responsible for this condition. CBD acts as an anti-inflammatory agent, maintaining sleep patterns and reducing motor symptoms like, bradykinesia, tremor, and rigidity.

CBD for Parkinson

Parkinson’s mainly affects the elderly associated with a deterioration in the working of the nervous system. The disease is linked to a drop in the production of dopamine, resulting in slow movement, muscular rigidity, and tremor. Sometimes, patients also experience digestive imbalance. Cannabinoids have effective antioxidants, brain protectors, and anti-inflammatory compounds, which slow down the progression.

Check best CBD for Parkinson’s here

More choices available

CBD for Frontotemporal Dementia

Frontotemporal dementia occurs when there is nerve cell loss in the frontal lobes and temporal lobes of the brain, causing symptoms of psychosis and depression. Cannabis for dementia stirs brain activity, controlling the symptoms associated with this disorder.

CBD for Huntington

Huntington is an inherited disorder that happens due to the death of brain cells. In the nascent stage, the signs are quite subtle, beginning with mood swings and irritation. CBD’s effectiveness can be used to manage the condition.

CBD Proper Dosage

If you’re considering giving cannabinoids to patients, you need to stick to a precise CBD oil dosage for dementia. There’re several considerations to make, including the patient’s age, weight, height, and severity of the condition. It’s vital to consult a doctor to determine the standard dosage for the patients.

CBD oil dosage can be calculated by “step-up method”, in which patients can consume 1-2mg in the first week and then increasing the dosage to 2-4mg in the next week if you notice changes in their behaviors. In a “step-up” table, the values increases and decrease as per the conditions. You can check our reviews for more information.

Forms of CBD for Dementia

Patients with Dementia can take CBD in any viable form. As a wide range of cannabidiol products are available in the market, you can choose an option that can be feasible for an elderly patient. Most of them prefer non-inhalable marijuana for dementia, such as oils, capsules, tinctures, gummies, and other edibles. CBD oil can last its effects for 4-5 hours and the effects start showing effects with half-an-hour. For immediate relief, you can stick to inhalers.

Ready to buy CBD oil for Dementia? Check our top 8 product list.

Bottom Line

CBD emerges as a ray of hope for deteriorating cerebral conditions. Dementia robs an individual’s thinking ability and other cognitive functions, making it troublesome to lead a normal life. The cannabinoids interact with CB1 and CB2 receptors of the endocannabinoid system, signaling the nerves in the brain.

CBD reverses dementia and makes patients happier and calmer. With its overwhelming benefits, the products have captured the attention of the public and slowly entered the medical and scientific fields.

Research has unveiled the excellent properties and benefits of cannabidiols that can improve the condition of dementia, Alzheimer’s, and other neurological disorders. Though cannabis is not a medication to treat the disorder, it is alternative prevention to anxiety, stress, and acts as a mood enhancer.

Any doubts about CBD’s curative characteristics? Our reviews can help you with the same.

Personal history leads physician to coconut oil for dementia relief

Dr Mary Newport, MD, gave a presentation about the effects of coconut in helping ameliorate the cognitive decline caused by Alzheimer’s disease at the recent Expo West trade show. It was a difficult personal experience brought Dr May Newport, MD, to her discoveries. Her late husband started to develop signs of early onset Alzheimer’s disease a number of years when he was only 51.

Husband started to be affected

“He was an accountant, and he started making big payroll mistakes. And he started to not be able to remember if he had taken things to the bank or the post office,”​ Dr. Newport told NutraIngredients-USAcalories.

“At first his doctors thought he might be suffering from depression,”​ she said. “Then he started to not be able to read a map.”

Dr. Newport’s husband was formally diagnosed with Alzheimer’s disease eight years after having started to show symptoms. By that time he had been unable to read for more than a year because of visual disturbances. His gait had become unsteady, and he had started to not be able to recognize certain relatives.

That was in 2008, and some experimental clincal trials were starting to get underway for various drugs to treat the condition. Dr Newport’s husband was screened for one of the trials but was found to have too low a score on the Mini Mental Status Exam (MMSE). He scored a 12 out of 30, but required a 16 to qualify for the trial.

‘Diabetes of the brain’

Dr Newport had done much research on the condition in the meantime, and came to understand it as a type of ‘diabetes of the brain.’ One of the first aspects of the disease, before the plaques and tangles of neurons start to become apparent, is that the brain starts to lose its ability to use glucose.

Best CBD Oil for Dementia

Is your prescribed medication for dementia giving you undesirable side effects ? Find out the best cannabidiol (CBD) oils you can use as an alternative for managing dementia-related symptoms and conditions.

Spruce 750mg Lab Grade CBD Oil
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

View Latest Prices

Mid-strength
Natural peppermint flavor
Made from 100% organic and natural ingredients
No other flavors
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

View Latest Prices

Pure CBD hemp
All natural
Approximately 300 drops total
No other flavors
Spruce 2400mg Lab Grade CBD Oil
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

View Latest Prices

Extra Strength
No artificial flavoring or colors
Made from 100% organic and natural ingredients
Tastes bitter
No THC-free option
Avida Full Spectrum CBD Oil Tincture 500mg
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

View Latest Prices

Light Spearmint flavor
Non-THC, Non-detected in drug test
No other flavor

Best Natural Alternative

cbdMD CBD Oil Tincture Natural 1500mg
  1. made using only CBD sourced from medical hemp
  2. available in many flavours
  3. safe for daily use

View Latest Prices

Various delicious flavors to choose from
Has vegan, organic, and gluten-free ingredients
Free shipping for this particular product within USA
World-class customer service team
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
CBDistillery THC Free CBD Oil Tinctures
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

View Latest Prices

60-Day Satisfaction Guarantee
Various strengths
Oil extracted from aerial plant parts of US grown industrial hemp
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Dropper is a bit shaky

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

View Latest Prices

Vegan and Gluten free
Has a third-party lab test
Wide variety of CBD strengths and sizes
Does not ship internationally
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

View Latest Prices

Pure CBD hemp
All natural
Approximately 100 drops total
No other flavors
A bit pricey compared to competitors

Best Flavor Range

Hemp Bombs 750mg CBD Oil
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

View Latest Prices

Wide variety of flavors
Lab test results are complete
30-day money-back guarantee
Incomplete information about the product
Does not ship to all international countries

Best CBD Oil for Dementia 2022

    Editor's Pick Best Organic Editor's Pick Best Seller Best Natural Alternative Best THC-Free Best Customer Rated Best Starter Best Flavor Range

Compare the Best CBD Oils for Dementia in 2021

Best CBD Oil for Dementia

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Mid-strength No other flavors
Natural peppermint flavor
Made from 100% organic and natural ingredients
Pros
Mid-strength
Natural peppermint flavor
Made from 100% organic and natural ingredients
Cons
No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Pure CBD hemp No other flavors
All natural
Approximately 300 drops total
Pros
Pure CBD hemp
All natural
Approximately 300 drops total
Cons
No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Extra Strength Tastes bitter
No artificial flavoring or colors No THC-free option
Made from 100% organic and natural ingredients
Pros
Extra Strength
No artificial flavoring or colors
Made from 100% organic and natural ingredients
Cons
Tastes bitter
No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Light Spearmint flavor No other flavor
Non-THC, Non-detected in drug test
Pros
Light Spearmint flavor
Non-THC, Non-detected in drug test
Cons
No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Various delicious flavors to choose from cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Has vegan, organic, and gluten-free ingredients
Free shipping for this particular product within USA
World-class customer service team
Pros
Various delicious flavors to choose from
Has vegan, organic, and gluten-free ingredients
Free shipping for this particular product within USA
World-class customer service team
Cons
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
60-Day Satisfaction Guarantee Dropper is a bit shaky
Various strengths
Oil extracted from aerial plant parts of US grown industrial hemp
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
60-Day Satisfaction Guarantee
Various strengths
Oil extracted from aerial plant parts of US grown industrial hemp
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Pure CBD hemp No other flavors
All natural A bit pricey compared to competitors
Approximately 100 drops total
Pros
Pure CBD hemp
All natural
Approximately 100 drops total
Cons
No other flavors
A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Vegan and Gluten free Does not ship internationally
Has a third-party lab test
Wide variety of CBD strengths and sizes
Pros
Vegan and Gluten free
Has a third-party lab test
Wide variety of CBD strengths and sizes
Cons
Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Wide variety of flavors Incomplete information about the product
Lab test results are complete Does not ship to all international countries
30-day money-back guarantee
Pros
Wide variety of flavors
Lab test results are complete
30-day money-back guarantee
Cons
Incomplete information about the product
Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

How We Rank
Our Ratings

How CBD Helps With Dementia

A 2017 study noted that CBD possesses anti-inflammatory and antioxidant properties that may help with dementia. Researchers also noted how CBD acts as a neuroprotectant to improve various brain functions (1) .

There are many types of dementia , like Alzheimer’s disease , vascular dementia , Lewy body dementia , Parkinson’s disease , Huntington ’s disease, and frontotemporal dementia (2) .

CBD’s potential to manage dementia is realized through its interaction with the endocannabinoid system (ECS), a system responsible for essential biological functions (3) . The ECS consists of two central cannabinoid receptors , CB1 and CB2.

CB1 receptors are responsible for cognitive functions , including movement, thinking, memories, and mood. Meanwhile, CB2 receptors affect pain and inflammation.

A study was conducted on ten dementia patients with severe behavior problems. Patients were given a combination of two phytocannabinoids , CBD and tetrahydrocannabinol ( THC ) (4) .

CBD and THC both come from the cannabis plant . However, CBD is non-psychoactive, while THC generates a high among users.

Based on the researchers’ findings, higher doses of CBD and THC improved the patients’ behavior problems. Patients also reported improvements in dementia symptoms, like muscle rigidity.

In one study on Alzheimer’s, a common form of dementia, it was found that CBD’s anti-inflammatory properties reduced critical elements in reactive gliosis (5) .

In gliosis, glial cells undergo a reactive change in response to damage in the central nervous system (CNS). Glial cells are the most abundant cells in the CNS, which surround, support, and provide insulation between neurons (6) .

CBD has been shown to reduce the negative impact of inflammation, oxygen buildup , and brain cell decline (7) .

Another study outlined CBD’s potential to prevent the production of large membrane proteins called amyloid -beta proteins (8) . These proteins are essential for neural growth and repair.

However, later in life, a corrupted form of amyloid -beta proteins can destroy synapses and eventually result in nerve cell death. This cell death leads to the loss of thought and memory in Alzheimer’s disease (9) .

According to the researchers, CBD may help suppress gene production related to Alzheimer’s.

Benefits of CBD Oil for Dementia

Several studies have suggested that CBD might have therapeutic benefits to the nervous system and its brain cells .

CBD vs. Neuroinflammation

According to a 2018 review of animal and human research data, CBD has anti-inflammatory properties that may reduce neuroinflammation (10) . The study also demonstrated that CBD may decrease inflammatory cytokine production.

Cytokines are signaling molecules that help in cell-to-cell communication in immune responses. These molecules are also responsible for the cells’ movement towards infection, trauma, and inflammation sites in the body (11) .

CBD vs. Oxidative Stress

A study on mice revealed that CBD possesses antioxidant , anti-inflammatory , and neuroprotective effects on oxidative stress . CBD also helps modulate glial cells and prevents the death of nerve cells (12) .

Oxidative stress is an imbalance that occurs when oxidants (reactive molecules that may cause inflammation) outnumber antioxidants (substances that protect cells from damage) (13) .

Oxidative stress is a major cause of different neurodegenerative diseases, specifically vascular dementia and Alzheimer’s. This imbalance is also linked to Parkinson’s disease and Huntington ’s disease.

CBD and Brain Stimulation

According to a 2017 study found in the Frontiers in Pharmacology journal, CBD promotes hippocampal neurogenesis or the production of new neurons in the hippocampus (14) .

Hippocampus is part of the brain that gets damaged by dementia. Hippocampal neurogenesis significantly decreases in patients with Alzheimer’s disease (15) .

A study on the treatment of Alzheimer’s suggested that the long-term use of CBD may help prevent the development of social recognition memory impairments in rodent subjects (16) .

The study also highlighted CBD’s antioxidant , neuroprotective, and anti-inflammatory properties . According to the researchers, CBD’s neuroprotective properties are related to its ability to reduce inflammation and oxidative stress .

Another study was conducted on patients with Parkinson’s to demonstrate CBD’s efficacy in treating psychosis associated with the disease (17) .

The test subjects were given a flexible CBD dose for four weeks, starting with an oral dose of 150mg CBD per day.

CBD may be useful in treating psychosis in patients with Parkinson’s disease . During the clinical trial , the test subjects did not experience any adverse side effects .

CBD vs. Nightmares

A study found that CBD may improve sleep-related conditions associated with rapid eye movement (REM) sleep behavior disorder (RBD) in patients with Parkinson’s disease (18) .

RBD is associated with low sleep quality and nightmares. Other sleep-related conditions include active behavior when one is dreaming and paralysis of muscles during nightmares.

CBD and Cognitive Functions

A 2018 study has noted that CBD’s long-term medical use may result in improved cognition , particularly in verbal learning, memory, and attentional switching (19) .

Meanwhile, results from multiple impairment studies on patients with schizophrenia showed CBD’s potential to improve cognition (20) . Preclinical models of cognitive impairment include Alzheimer’s disease , neuro-inflammatory disorders , and neurological disorders.

CBD vs. Anxiety and Depression

People with dementia may also experience anxiety and depression (21) . According to a 2018 study published in Frontiers in Immunology , CBD has the potential ability to alleviate the symptoms of depression (22) .

The researchers noted that CBD’s anxiety-reducing and antipsychotic effects may help with symptoms of epilepsy, social phobia, schizophrenia, bipolar disorder, and Parkinson’s disease .

A study also reported that CBD has anxiolytic (anti-anxiety) effects that may help with anxiety disorders, such as generalized anxiety disorder, social anxiety disorder, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder (23) .

CBD Dosage and Delivery Methods for Dementia

Dosage

Based on a 2017 review, there is no standard CBD dosage chart for any specific medical condition , like dementia (24) . The review also noted that humans and animals respond uniquely to different doses of CBD.

The general rule for dosing with CBD i s to begin with small amounts, especially if you are taking it for the first time.

It is essential to take note of your body’s reaction to CBD. If there are no adverse effects observed, you may gradually increase the dosage to maximize CBD’s potential health benefits.

It is recommended to start with a small dose of 1mg to 2mg CBD daily for one week. Then, increase the dosage by 2mg to 3mg CBD weekly until you notice significant symptom improvements (25) .

The CBD dosage should be based on the patient’s body weight—the heavier the individual, the larger their dose. The standard dose for average adults is approximately a maximum of 5mg.

Before adding CBD to their medication regimen, dementia patients or their family members should consult a doctor.

Methods of Delivery

You can find various forms of CBD products on the market. For people with dementia, it is recommended to administer CBD in gelcap form (26) .

Compared to CBD tinctures , gelcaps help in the administration of consistent amounts of CBD. Elderly patients may also feel more familiar with swallowing pills.

Patients may also take CBD orally using other product forms, such as CBD oil , sprays, gummies , or capsules. CBD oil can be mixed with food and beverages if CBD administration to dementia patients is complicated.

You may take tinctures sublingually (under the tongue) using a dropper . Hold for 60 to 90 seconds before swallowing for more efficacy.

The sublingual method takes about 15 to 30 minutes to sta rt taking effect in the system. Results may last up to a few hours (27) .

Meanwhile, CBD oil may be used topically during massages to relieve the pain felt by patients. Various CBD topical formulations available to patients include salves, gels, lotions, balms, and creams.

It is recommended to purchase topical products that use CBD micellization, nanotechnology, or encapsulation since CBD has limited absorption when used topically (28) .

The technologies and methods mentioned above guarantee that CBD, as an active ingredient, is transmitted through dermal layers and does not only stay on the skin (29) .

After applying CBD topical to your skin, you may notice the effects within 30 to 90 minutes (30) .

Inhaling CBD through vape oils and pens provide fast-acting effects. However, vape products are not advisable for dementia patients who are usually elderly.

Side effects of vaping include dry mouth and throat, coughing, and shortness of breath (31) . Vape use may also cause lung diseases, such as collapsed lung and lipoid pneumonia (32) .

CBD and Other Alternative Treatments for Dementia

People have been exploring alternative treatments for dementia, as the commonly used medications often have adverse effects. These effects may be detrimental, especially to elderly dementia patients .

Pharmaceutical medicines for dementia may cause nausea, vomiting, appetite loss, diarrhea, fatigue, muscle pain, headaches, dizziness, itchiness or rashes, sleep problems, agitation or aggression, and hallucinations (33) .

Acupuncture

Several studies have explored acupuncture treatment as a potential remedy for dementia. Acupuncture is a vital component of traditional Chinese medicine believed to enhance the body’s flow of energy (34) .

Unlike massage therapies that focus on stimulating the blood flow and movement in the body, acupuncture targets specific body points using thin needles (35) .

According to a study published in the Evidence-Based Complementary and Alternative Medicine journal, acupuncture is more effective when used with Western and herbal medications (36) .

The researchers noted that acupuncture has mixed efficacy in treating dementia and cognitive impairments .

Another study demonstrated that acupuncture elicited significant improvement in the sleep quality of elders with dementia (37) . Over the treatment period, researchers observed significant gain in resting and sleep time.

The researchers found that acupuncture has a beneficial effect on the cognitive status and daily activities of dementia patients .

Herbal Supplements

Herbal supplements may also be used as an alternative treatment for dementia.

Some of the most commonly studied and used herbs include Ginkgo biloba , Huperzia serrata , Curcuma longa (turmeric), Panax ginseng, Panax notoginseng, Bacopa monnieri (water hyssop), and Camellia sinensis (tea plant) (38) .

Numerous clinical trials have shown that ginkgo helps with memory loss and concentration and decreases anxiety in patients with dementia (39) .

According to reports, a standard preparation of the ginkgo herb may improve neurocognition and enhance the daily activities of vascular dementia and Alzheimer’s patients (40) .

CBD

Other alternative remedies may only treat a few aspects of dementia. Thus, some studies suggest that the use of cannabis -related products, like CBD, may have more advantages (41) .

CBD’s neuroprotective and antipsychotic properties have the potential to alleviate the symptoms associated with dementia.

Using CBD for Dementia: Risks and Side Effects

CBD is generally well-tolerated and safe to use (42) . According to the National Institute on Drug Abuse (NIDA), CBD is classified as “non-addictive (43) . ”

The World Health Organization (WHO) has not recorded any case of CBD dependence in humans (44) . Thus, it was concluded that CBD is not a substance that has the potential for abuse.

However, risks and side effects may still occur. Possible adverse reactions to CBD may include (45) :

  • nausea
  • fatigue
  • dry mouth
  • drowsiness
  • diarrhea
  • mood changes, like irritability
  • loss of appetite
  • gastrointestinal problems
  • liver damage

CBD may also interact with other medications and supplements and raise their levels in the bloodstream.

The typically prescribed treatments for dementia are cholinesterase inhibitors. These inhibitors have been shown to have a modest effect on symptoms of dementia , like cognition (46) .

Donepezil and galantamine are some of the most commonly used cholinesterase inhibitors. Both treatments are metabolized by a group of enzymes called cytochrome P450 (47) .

Caution is advised when taking CBD with dementia medications to avoid drug interactions.

Since CBD may inhibit liver enzymes, the compound has the potential to reduce the efficacy of certain dementia medications (48) .

Another safety concern is CBD’s lack of regulation from the United States Food and Drug Administration (FDA). Many CBD products are being primarily marketed with unsubstantiated therapeutic claims and sold as supplements (49) .

The FDA currently does not regulate the purity and safety of dietary supplements. Some CBD companies continue to sell products online without thorough testing (50) .

The only FDA-approved drug derived from purified CBD is Epidiolex. This product is used to treat seizures associated with two rare forms of epilepsy, such as Lennox-Gastaut syndrome and Dravet syndrome (51) .

How to Choose the Best CBD Oil for Dementia

Before buying any CBD product , it is important to know the three types: full-spectrum, broad-spectrum, and CBD isolates.

All the parts of a Cannabis sativa plant are used in a full-spectrum CBD oil . There are also trace amounts of THC , terpenes , flavonoids, fatty acids, and essential oils.

Some studies suggest that full-spectrum CBD oil is the most effective type of CBD oil because all the ingredients of the cannabis plant synergize for maximum therapeutic benefits (52) . This synergistic effect is known as the entourage effect.

However, note that THC may be detected in drug tests. THC also causes psychoactive effects.

If you want to avoid the risk of getting high, broad-spectrum CBD is more recommended. Broad-spectrum CBD oil contains the same components as full-spectrum CBD except for THC .

People looking to use pure CBD or avoiding its other components due to allergies may use CBD isolates. This type of pure CBD oil is made from isolated cannabidiol .

There is a significant difference between CBD oil and hempseed oil. CBD is derived from a hemp plant’s stalks, flowers, and leaves.

Meanwhile, hempseed oil is primarily obtained from raw hemp seeds. There may be trace amounts of CBD in hempseed oil or none at all.

The other things you should consider in choosing the best CBD oil product include the following:

  • Identify the CBD product ’s source of hemp. The most common hemp sources include Colorado , Oregon, and Kentucky.
  • Choose high-quality CBD products that are derived from non-GMO, organic hemp.
  • Find out which method is used in extracting CBD oil . According to a report, CO 2 extraction is recognized as a safe process and recommended by the US FDA in pharmaceutical manufacturing (53) .
  • CBD companies should give consumers access to third-party lab reports and analyses. Accredited third-party labs issue certifications on a CBD product ’s components and quality.
  • If you have a loved one with dementia , encourage them to consult with a medical professional first before letting them use any CBD product .
  • Before purchasing from a retailer or dispensary , ensure that CBD’s sale or use is legal in your state.
  • Make sure to research the CBD brand and check reviews from other customers when purchasing online.

Legality of CBD

When the 2018 Farm Bill was passed, hemp-derived CBD containing less than 0.3% THC became legal (54) . This bill also allowed the growth, production, and manufacturing of hemp on the federal level.

Although CBD is easily accessible in many parts of the United States, state laws may have varying degrees of restriction.

Some states have laws permitting cannabis oil with a high concentration of THC (55) . Under a state’s medical marijuana program, patients with qualifying conditions may have legal access to medical cannabis (56) .

Medical marijuana patients may require an official diagnosis and prescription from a licensed physician.