is.cbd oil.good.for.dogs.braind

5 Amazing Benefits CBD Oil Can Do For Your Dog

CBD, or cannabidiol, is a compound found in cannabis, aka marijuana.

CBD oil is non psychoactive so it will not make your dog “high,” it will only relax your dog.

Now how is CBD oil beneficial for your dog? Well, I did some quick research to find out what CBD oil can do for your dog.

Studies show that CBD oil can be a powerful painkiller, an anticonvulsant, anxiety reducer, appetite stimulator, and a tumor growth inhibitor.

1. CBD Oil Relieves Pain

CBD oil is a natural painkiller. It suppresses and interrupts the pain signals in your dog’s brain. It can also help alleviate acute and chronic pain.

Additionally, CBD oil can help reduce chronic inflammation.

Common health problems CBD oil can help your dog with:

  • Arthritis/ Joint Pains
  • Sprains & Strains
  • Recover From Surgery
  • Torn Ligaments
  • Hip Dysplasia

CBD oil has potent anti arthritic therapeutic properties that assist and help with pain and protect your dogs joint.

Furthermore, CBD can help improve the quality of life of your arthritic dog. Your dogs pain will be more tolerable and your dog will live comfortably.

2. Reduces The Risk of Seizures

CBD oil can help control seizures, tremors, tics, and spasms.

Also, CBD can help reduce the duration of seizures and decrease the amount of seizures.

Preliminary research suggests that CBD can help restore rapid, uncontrolled firing of neurons in your dog’s brain.

Common symptoms of a seizure are:

  • Paddling (constantly moving the feet as if in water)
  • Suddenly Collapsing
  • Foaming of the mouth/ Excessive Drooling
  • Whining or Barking
  • Temporary Loss of Consciousness
  • Stiffness
  • Twitching & Jerking
  • Dazed or Confused

3. Reduces Anxiety & Stress

CBD oil contains compounds that work with the Endocannabinoid system to produce calming effects.

Research suggests that CBD can help boost serotonin levels in the brain. However, there is still not enough research to completely validate this theory. What we do know is that the body has cannabinoid receptors throughout the central nervous system. When the body naturally releases Endocannabinoid chemicals they connect with these receptors to stimulate serotonin.

Common forms of anxiety in dogs are:

  • Separation Anxiety
  • Noise Anxiety
  • Travel Anxiety
  • Phobias

Common Symptoms of Dogs With Anxiety:

  • Chewing (furniture, rubbish, shoes, etc.)
  • Aggression
  • Urinating & Defecating (inside the house or crate)
  • Tremors

4. Increases Appetite

Sometimes our dogs don’t eat and this can be due to many reasons, like drugs or toxins, or even health problems.

CBD oil may help increase your dogs appetite.

The National Cancer Institute reports that CBD oil can help stimulate your dog’s appetite.

CBD regulates appetite hormones, helping your dog feel satisfied and stimulating the urge to eat.

CBD oil also prevents nausea. Studies show that CBD oil targets specific receptors to activate a bodily response that suppresses the feeling and urge of nausea.

5. Fights Cancer

Cancer and malignant tumors can be fatal, treatments can also cause painful side effects.

CBD oil has been found to inhibit the growth of tumors. Studies also show that CBD has the ability to stop the growth of cancer cells and increase the death of tumor cells .

How does CBD oil do this?

Well, CBD oil helps the immune system fight against foreign cells and kill cancer cells. In addition, CBD kills cancer cells by blocking the ability of cancer cells from producing energy. Lastly, the anti tumor properties contained in CBD oil help inhibit and slow the growth of glioma cells.

How To Give CBD Oil To Your Dog

The right dosage depends on your dogs weight and size. It is also best to use CBD oil specifically formulated for dogs. It will be much easier to give the same dose of oil to your dog every time.

CBD oil is non toxic so it won’t produce any negative side effects if you give your dog too much CBD.

However, be aware that it will make your dog feel drowsy if given too much oil. Do not panic though, these effects are only temporary and won’t cause your dog any harm.

If your dog is new to CBD oil then it is best to start off with a small dose and gently increase the dosage after several weeks. This gives you time to measure your dog’s reaction after a few weeks of taking CBD.

To get the most out of CBD oil, give your dog CBD oil twice a day. Once in the morning and once at night.

I have provided two examples to help you have a better idea of how much oil to give your dog. I have also provided dosage levels to calculate the right dosage for your dog.

  • A 30 kg labrador would need 15 drops of CBD oil.
  • A 10 kg french bulldog would only need 5 drops of the oil.

Dosage Levels:

  • Low Dosage — 0.022 mg/lb or 0.05mg/kg
  • Average Dosage — 0.068 mg/lb or 0.15 mg/kg
  • Strong Dosage — 0.136 mg/lb or 0.30 mg/kg

Giving your dog CBD in its oil form is not the only way he/she can benefit from CBD. There are also other ways you can give your dog CBD.

  • CBD Capsules
  • Topicals
  • Cannabis Oil
  • CBD Tincture
  • Dog Treats with CBD

If you don’t know where to start then here are a few examples of how to give CBD to your dog.

  • Mix CBD oil in your dog’s treats
  • Find a CBD product your dog will absolutely love!
  • If your dog is picky, be direct and apply it directly to your dogs mouth by using a dropper or spoon.
  • Add the CBD oil to your dogs food

Below is a list of the top best brands of CBD for your dogs:

  • Therabis- best for anxiety
  • Honest Paws- Comes in 3 formulas, pain reliever, health restorer, and calming
  • Hemp Chews- best for arthritis/ joint pain
  • Zest Paws- best for behavioral problems (calming your dogs excessive biting)
  • Natural doggie organic CBD infused coconut oil dog super supplement

Does Your Dog Need CBD Oil?

It’s up to you, but there are positive reviews out there and its popularity is booming.

Not only that, it can be very beneficial to your dog and its a safe, natural approach to improve your dogs health.

If your dog has any of these common health problems listed above then I highly recommend you try CBD. It can be a good alternative to medication that may be causing your dog unwanted side effects.

You can also use this oil to help your dog relax.

Talk to a holistic vet to see if CBD oil is the best choice for your dog.

Can CBD Oil Help Dogs With Dementia or CCD?

When your dog enters their senior years, you may notice a change in their behavior. It can be tough to spot at first, but if your senior dog is showing behavioral changes, it may be time to take them to the vet to find out if they have Canine Cognitive Dysfunction (CCD).

CCD is also known as dog dementia, sundowners, or “dogzheimers” but all are terms for the same cognitive issues.

If your dog is diagnosed with CCD, it can be heartbreaking. Nobody likes to see their best friend suffer, and as your pet ages, you may feel helpless. But, knowing ways to prevent CCD, knowing the symptoms of CCD and making your pet’s twilight years comfortable with all-natural treatments can be beneficial in minimizing stress.

Table of Contents

Signs of CCD or Dementia

Recognizing dementia or CCD in dogs is not quite as straightforward as it is in humans. Your dog cannot tell you that they forgot something, they cannot tell you that they are scared or worried or don’t know where they are. So as your pet ages, it is important to pay attention to their habits and routines so that you can know when something is off.

Since there is no easy test to diagnose a dog with CCD, it is important that you write down any observations you have made and bring that paper to the vet.

Your veterinarian may be looking for the following symptoms:

Disorientation and Increased Anxiety

If your dog is experiencing signs of CCD or dementia, you may notice her pacing behind closed doors. The reason for the pacing is usually due to being lost. She may not remember how to exit the room or might not remember the home at all. You may also notice her gazing into space; almost as if she is staring into the wall. This could be a house she has lived in for years. She may simply not remember it due to a declining mental state.

This will lead to increased anxiety. That’s as to be expected. Think about what would happen if we were completely lost and didn’t know where we were or where to go. We would become anxious ourselves.

Excessive barking may occur. You know your dog’s bark and what each one means. You’ll hear the anxiety or nervous bark along with some possible howling. She’s letting you know she’s in distress.

Lack of Bowel Control

Even if your dog has the best track record for using the bathroom outside, he might start peeing and/or pooping inside the house. Stay calm if this occurs; this isn’t his fault. He may lose control of his bowels due to anxiety or another underlying condition. Comfort her and let her know everything is going to be okay. If you remain optimistic, she is more likely to remain optimistic.

Changes in Appetite

You may notice a decrease or increase in appetite with CCD or dementia. Usually, this is due to increased anxiety, but it could be she just forgot to eat. She may not eat until she remembers; or if you place her food bowl directly in front of her.

Changes in Hearing and/or Vision

It is important to note that changes in hearing or vision can cause some of the same symptoms. For example, a dog who is losing hearing or vision may become disoriented and may have increased anxiety as a result. Have your vet test for hearing and vision problems to rule out CCD.

How to Help Your Dog Through the Mental Decline

There is no cure-all for dementia or CCD. However, there are ways that you can keep your pet comfortable and slow their decline.

Routine, Diet, and Essential Oils

Maintaining a regular routine can help your dog maintain a sense of balance, even if they have trouble remembering the routine. It can also soothe their anxiety to listen to soft music and exercise regularly. Incorporating omega-3 fatty acids into their diet can also help brain-health.

Additionally, essential oils, like lavender , can provide a calming effect and can help senior dogs feel comfortable. Many pet owners also turn to melatonin to help their senior pet rest at night.

It is important that you consult your veterinarian (we recommend a holistic vet when possible) to discuss supplements that can help slow decline and to discuss all of your options.

CBD For Cognitive Decline

CBD has been proven to help treat everything from seizures to anxiety and depression, and neurological issues in dogs. In fact, the U.S. government has a patent on cannabis as a neuro-protectant .

CBD can be used as a preventative measure against dementia and has been proven to help brain function. In dogs, CBD can not only help prevent dementia or CCD from beginning in the first place but if your dog has CCD , it is an excellent treatment option.

CBD may not fully bring back your dog’s memory or old behaviors, but it can ease the anxiety and stress related to dementia and can help your dog stay calm and comfortable in their senior years. Full Spectrum – Hemp Extract is rich in omega-3 and omega-6 fatty acids, which contribute to brain health.

If your pet has dementia, we recommend our HEAL CBD oil for dogs, as it has 1100 mg of full-spectrum CBD and has a perfect balance of fatty acids and omega-3 and omega-6 fatty acids.

CBD can safely be incorporated into your pet’s diet early on to use as a preventative measure, and as your pet ages, it is a more natural way to treat the changes that come with age. Whether your pet is suffering from dementia or just aches and pains associated with aging, when you start using CBD oil for dogs, your pooch will thank you for it.

To learn more about keeping your senior pet healthy and happy, visit CBDDogHealth.com or AngelaArdolino.com .

Research on CBD for Dementia and CCD

The AHVMA recently published a Scientific Review on the Integrative Treatment of Canine Cognitive DysfunctionScientific Review on the Integrative Treatment of Canine Cognitive Dysfunction, by Janice L. Huntingford, DVM, MS.

“CBD affects both GABA and serotonin receptors and has been shown to have anxiolytic properties (64). A review by Maroon and Bost discussed the neuroprotective benefits of CBD, which include decreasing the production of inflammatory cytokines, influencing microglial cells to return to a ramified state, preserving cerebral circulation during ischemic events, and reducing vascular changes and neuroinflammation (65). CBD has been shown to reverse or prevent the development of cognitive defects in a mouse model of AD (66). Other studies show that a combination of tetrahydrocannabinol (THC) and CBD in a full-spectrum product reduced memory impairment in AD mice. In other murine studies, cannabinoids were found to reduce oxidative stress, microglial activation, and neuroinflammation; facilitate removal of Aβ plaques and reduce their production; and decrease tau protein aggregation (66). Cannabinoids have been used in humans to reduce the signs of dementia in AD patients. Caregivers report decreased distress, agitation, and aggression and improvement in mood, appetite, and sleep quality in AD patients taking cannabis oil (67). Because CCD is a model for AD, this would suggest that cannabinoids may work in a similar way in canine patients.”

Dosing for Dementia with Full-Spectrum Hemp Extract

Dogs with dementia are recommended 35-50 mg of CBD per day, but this can vary by age and condition (many dogs with dementia are in their senior years). Split the daily dose into multiple applications a day. This will maintain blood concentration of CBD throughout the day. Additionally, it will lower the possibility of any stomach upset as your pet’s gut gets used to an oil tincture.

Book a Consultation and Ask All Your Questions

Here at CBD Dog Health, we know trying something new can be difficult, especially when it comes to our beloved furry family. Luckily, you can book a consultation to discuss your dog’s individual situation to help you feel more at ease with something new and become accustomed to the dosage.

Best CBD Oil for Brain Health – February 2022

A 2018 review posted in the Surgical Neurology International mentioned how CBD is of particular interest due to its many potential therapeutic benefits and lack of side effects in a variety of neurological diseases and conditions (5) .

The review also mentioned how CBD might possess therapeutic properties for brain function.

The authors further discussed more significant benefits of CBD among test subjects with PTSD, depression, and post-concussion syndrome.

In addition to its potential to improve mental health, CBD has been observed to have neuroprotective properties.

This characteristic might benefit patients with neurodegenerative disorders and motor function disorders like Alzheimer’s disease (AD) and Parkinson’s Disease (PD) (6) .

Many of these neurodegenerative disorders are progressive. The lack of cure may have contributed to some people’s decision to turn to alternative treatments.

CBD Oil for Improved Memory

A 2018 review posted in Cannabis and Cannabinoid Research Journal shared that CBD treatments might confer benefits to mental health and cognitive function.

Furthermore, the beneficial outcomes were observed from test subjects with ongoing cannabis use (7) .

A 2015 study posted in the Journal of Alzheimer’s Disease mentioned how a combination of CBD and tetrahydrocannabinol ( THC ) had reduced learning impairments among animal test subjects (8) .

The study continued with the observation that CBD showed promising results in reducing hypertrophy of glial cells and inflammatory-related molecules in the brain (9) . This resulted in improvements in preserving the memory of the animal subjects.

Improved memory has also been observed among CBD users. Using hair analysis, a study examined individuals who have been naturally exposed to CBD .

They found that CBD has the potential to improve memory and other cognitive performances (10) .

CBD Oil for Pain Relief and Improved Sleep

Some individuals suffering from chronic pain in various parts of the body may also develop insomnia (11) .

Lack of sleep often results in cognitive impairments , such as memory loss and poor motor functions.

A study posted in Therapeutics and Clinical Management reported that CBD demonstrated analgesic and anti-inflammatory effects (12) .

This potential to treat and manage pain might improve sleep among individuals with chronic pain .

A 2017 review in Current Psychiatry Reports summarized the effects of CBD and its therapeutic potential for treating insomnia .

The study explained that CBD might be a promising remedy for REM sleep behavior disorders and daytime sleepiness (13) .

Additional studies have supported the hypothesis founded by the previous review. One study in particular conducted tests on how healthy adults reacted to daily doses of CBD .

A 2019 large case series published in The Permanente Journal shared outcomes of sleep and anxiety scores of 72 healthy human subjects.

The study came to a result that demonstrated several improvements among subjects who took CBD.

During the first week, 57 out of 72 individuals have improved their anxiety scores, while 48 out of 72 have improved sleep scores (14) .

CBD Oil for Headaches

Migraine is a common disabling disorder in the brain that can lead to other problems that aggravate their tendency to headaches, such as anxiety and depression (15) .

According to the US Food and Drug Administration (FDA), migraine is a condition that affects 37 million people in the U.S. and 10% of the worldwide population (16) . They also added that migraine affects women three times more than men.

Since the middle ages, physicians have used cannabis plants , such as hemp ( cannabis sativa ), to treat migraine and headaches (17) .

A 2018 review in Frontiers in Pharmacology mentioned that CBD must be explored as a possible migraine treatment (18) .

CBD ’s affinity in binding to cannabinoid 1 (CB1) receptors in the brain may influence stabilization in the endocannabinoid system (ECS). This binding activity may result in counteracting migraines and blocking neuroinflammation (19) .

CBD Oil for Mental Health

In 2015, Neurotherapeutics published a study that discussed how CBD might have anxiolytic and anti-inflammatory properties (20) .

The study further expounded on how CBD might block reconsolidation and adverse memories in animal test subjects, making it a potential contender in treating post-traumatic stress disorder (PTSD) and panic disorder (PD).

In the same study, the authors discussed how clinical trials on healthy human test subjects demonstrated CBD ’s efficacy in reducing anxiety and other relevant disorders, including PTSD, PD, obsessive-compulsive disorder, general anxiety disorder , and social anxiety disorder (21) .

The findings are later supported by another study in 2018 published in Frontiers of Immunology.

The authors of the study hypothesized that CBD might have a pharmacological effect comparable to mood stabilizers (22) .

CBD ’s anti-anxiety, antidepressant, anticonvulsive, and antipsychotic actions make it a valuable subject for further research (23) .

A study posted in Translational Psychiatry discussed how CBD moderately inhibits the degradation of anandamide , an essential omega-6 fatty-acid neurotransmitter.

The study tested the potential antipsychotic effects of CBD by administering it to patients with psychotic symptoms for 28 days (24) .

Results showed that the improvement in patients treated with CBD is comparable to that of patients treated with amisulpride, a standard antipsychotic drug (25) .

CBD Oil for Neurodegenerative and Neurological Disorders

A review posted in the British Pharmacological Society has attributed the neuroprotective , neurotransmission, and neurogenesis (forming of new neurons) properties of CBD .

These properties have been observed in numerous chronic neurodegenerative disorders (26) .

The review added that CBD , as a monotherapy or in combination with other phytocannabinoids , has demonstrated significant effects among test subjects with neonatal ischemia, Hungtington’s disease, multiple sclerosis , and Parkinson’s disease (27) .

CBD ’s significant neuroprotective effects have been attributed to its anti-inflammatory and antioxidant properties.

The review ended with the hypothesis that CBD has shown valuable influences on many conditions involving brain functions (28) .

In June 2018, the FDA approved a drug ( Epidiolex ) that contains CBD as an active ingredient. This drug is used for two rare and severe forms of childhood epilepsy , Dravet syndrome, and Lennox-Gastaut syndrome.

Epidiolex is the first FDA -approved drug that contains purified extracts from marijuana plants (29) .

A 2019 study posted in Molecules discussed how CBD ’s anticonvulsant properties may help with epileptic seizures among children.

Clinical trials have compared CBD to other antiepileptic drugs. Most assessed that CBD is safe among infants, children, and teenagers (30) .

Still, it is strongly advised that individuals must first consult with a pediatric epileptologist before considering CBD for their children for any reason.

How CBD Oil Works to Help With Brain Health

The endocannabinoid system is made of G-protein receptors located throughout the human body , such as cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2).

These receptors are present mostly in the central nervous system and peripheral nervous system (31) .

The ECS has been studied for its regulatory function on several health and mood conditions.

It has been discussed in a study published in Pharmacological Reviews that modulating the ECS might result in many therapeutic promises in a wide range of pathological conditions and diseases (32) .

The ECS has been observed to hold influence over depression, neurogenesis, cognition, learning, and memory (33) .

Moreover, the ECS is believed to have receptors present in the immune system . It is speculated that Immune cells secrete endocannabinoids and express both CB1 receptors and CB2 receptors (34) .

A study published in the British Journal of Pharmacology explained how cannabinoids , such as THC and CBD , bind to CB1 and CB2 receptors (35) .

Using animal test subjects, the study came upon CBD ’s therapeutic potential to treat many symptoms.

A 2015 review posted in Neurotherapeutics explained how CBD ’s interactions with several receptors like CB1 and serotonin receptors ( 5-HT1A ) have the potential to regulate fear and anxiety behaviors (36) .

Pros and Cons of CBD Oil for Brain Health

The Pros
  • CBD might have the potential to improve memory and other cognitive performances (37) .
  • In a study, CBD showed potential in reducing learning impairments among animal subjects presenting with Alzheimer’s disease (38) .
  • CBD might be a promising remedy for REM sleep behavior disorders and daytime sleepiness (39) .
  • In a study, CBD demonstrated analgesic and anti-inflammatory effects, which may promote good sleep among individuals with chronic pain (40) .
  • CBD may help in reducing migraines by blocking neuropathic pain and neuroinflammation (41) .
  • CBD might have a wide range of therapeutic properties, including anxiolytic (42) , antipsychotic (43) , and antidepressant effects (44) .
  • CBD is safe and well-tolerated among human and animal subjects.
  • The World Health Organization (WHO) acknowledged CBD is non-addictive and safe for daily intake (45) .
  • One does not need prescriptions to buy CBD oil .
  • CBD is legal in most of the United States, (46) as long as THC (the cannabinoid that produces psychoactive effects ) content does not exceed 0.3%. CBD is also legal in some countries in Europe and Canada, but prescriptions may be needed.

The Cons

  • CBD may have a few side effects , such as diarrhea, fatigue, loss of appetite, and sleepiness (47) .
  • CBD can be expensive. Some brands sell high-quality CBD oil up to 400% per few thousand milligrams.
  • CBD may interact with other medications. It is not advisable to use CBD in conjunction with other medicines without conducting research first.
  • In the United States , CBD is currently unregulated. Individuals are advised to research before buying CBD .
  • CBD is not a cure-all . More studies are needed to verify it’s potential health benefits .

How Does CBD Compare to Other Alternative Treatments?

Alternative treatments for boosting brain health may vary. Individuals who use the natural approach may often opt for particular herbs and spices , such as sage, turmeric, ginseng, and ginkgo biloba.

Ginkgo biloba is believed to have properties that improve memory among individuals with Alzheimer’s disease .

Ginkgo biloba supplements do not need a prescription. However, there are reported cases of side effects of this herb, like stomach problems and headaches (48) .

Salvia or sage has shown evidence for its ability to enhance cognitive function and neuroprotection.

Many cultures have used sage for thousands of years. Scientists acknowledge that this inherited tradition has merit (49) .

Like sage, hemp ( cannabis sativa ) has a rich history dating back to the 18th century. The Arabic physicians from the medieval Islamic world used hemp extracts for pain-relieving, anti-inflammatory, analgesic, fever-reducing , and antiepileptic properties (50) .

A popular food supplement for the brain is omega-3 fatty acid. Commonly found in food , such as fish, soybeans, and flaxseed, omega-3 fatty acid is rich in eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

A 2015 study published in Frontiers in Aging Neuroscience acknowledged the potential benefits these fatty acids may have on improving cognitive functions and enhancing neuroprotection (51) .

Like omega-3 fatty acid, CBD oil is natural because it is derived from industrial hemp plants. The oil pressed from hemp seed, in particular, is a rich source of polyunsaturated omega-3 fatty acids, which are essential for human health (52) .

Many manufacturers use only non-GMO organic hemp to cater to vegan and vegetarian communities. Many CBD oil products use hemp seed oil as the carrier oil to take advantage of its rich fatty acid.

How to Choose the Right CBD Oil for Brain Health

CBD oil comes in three types of concentrations. The best type varies per individual’s needs.

For individuals suffering from symptoms associated with neurodegenerative conditions such as Alzheimer’s disease , Parkinson’s disease, and dementia, the best CBD oil is the full-spectrum.

CBD , combined with THC and other cannabinoids , may provide therapeutic benefits (53) .

Full-spectrum CBD oil contains all the cannabinoids present in the hemp plant, including THC (0.3% or lower), the psychoactive compound.

Taking in all the benefits from the cannabinoids in one dosing produces the entourage effect. This means that an individual gets a supposed boost in health by taking all the compounds present in hemp.

For individuals who want to achieve the entourage effect without the presence of THC , the best CBD oil to use is the broad-spectrum type. Broad-spectrum CBD oil contains all the cannabinoids without THC .

Some individuals cannot have any trace amounts of THC in their system due to work or other personal reasons.

For people who cannot tolerate other cannabinoids , they can benefit from CBD isolates. This formulation contains >99% purified CBD .

The CBD industry remains unregulated. This is why individuals are advised to research before buying. When shopping for CBD oil , one must always look for the product’s certificate of analysis (COA).

The COA is a third-party laboratory test result that indicates the concentration of the cannabinoids contained in the product.

The COA also confirms that the CBD product is free from harmful chemicals , like heavy metals and pesticides.

One can find the COA on the brand’s company website. There should be a COA for every batch produced by the manufacturer.

Knowing the extraction method is also essential. The CO2-extraction is a process that does not involve adding heat or solvents.

This method keeps the CBD oil concentration pure and free from harmful chemicals.

Additional tips on shopping for the best CBD oil

  • One must always choose non-GMO, organic industrial hemp oil from legitimate brands.
  • Read testimonials and brand reviews from other customers. Check the rating of each product.
  • When buying CBD vape cartridges, make sure the concentration does not contain fillers and toxic substances, like propylene glycol and polyethylene glycol.

CBD Dosage for Brain Health

There is no medically accepted dosage for CBD oil . Although CBD oil has been reported to be well-tolerated and safe (54) , caution is still advised, especially to first-time CBD users.

CBD beginners must always start with a low dose. One can gradually increase the dose as the body gets used to CBD oil .

When taking CBD oil for a brain- or central nervous system -related condition, researchers suggest a dose of less than 1 milligram to 50 milligrams of CBD per kilogram per day (<1 and 50 mg/kg/d) (55) .

The authors of the review recommended the amount by organizing a clinical trial involving patients with schizophrenia, epilepsy, social anxiety disorder , and dystonic movement disorder.

How to Take CBD Oil for Brain Health

The same group of doctors who conducted the clinical trial (previously mentioned) used the oral delivery method, such as capsules, oral solution, and sublingual spray (56) .

For individuals who want to partake in CBD ‘s overall potential health benefits , they can take CBD tinctures, CBD capsules, or CBD gummies. The oral method ensures that CBD stays in the system longer.

For individuals experiencing headache pain or a severe migraine, a faster delivery method is vaping. This method ensures that CBD goes into the system within minutes after delivery.

However, vaping may have several side effects. It has also been linked to lung disease (57) .

There are also other ways to administer CBD , such as creams, essential oils, bath bombs, and teas. These methods are recommended for individuals who want to maintain overall wellness and relaxation.

Can CBD Oil Make Dementia Better Or Worse?

Although there are studies that acknowledge CBD ’s potential to treat epilepsy and improve symptoms of motor function disorders, its efficacy on individuals with dementia remains in an academic setting.

There was some evidence from a preclinical study that CBD might interact with receptors, resulting in blocking neurotoxicity and increased cell survival (58) . However, there was no mention of CBD making the symptoms worse.

The Canadian Agency for Drugs and Technologies in Health released a report in 2019 that mentioned how dementia patients who were given CBD with dronabinol (an FDA -approved synthetic version of medical marijuana ) showed improvement, significantly reducing their caregiver’s burden (59) .

The report also mentioned that there were significant improvements in agitation, irritability disinhibition, aberrant behavior, and nocturnal behavior disorder.

Since studies on CBD remain in preliminary stages and dronabinol may only be taken with a prescription, it is advisable to consult a physician before using CBD for dementia.

Can CBD Oil Help With Brain Injury?

A 2017 animal study posted in Frontiers of Pharmacology noted that CBD might help with traumatic brain injury .

The study mentioned that CBD activated the g-protein-coupled receptor, which produces increased adenosine concentrations that downregulate inflammatory cells (60) .

Adenosine is an organic molecule and a building block of ribonucleic acid (RNA), which is essential for forming new brain cells .

The study concluded that CBD might be a promising subject for future investigations in the study of neuroinflammation caused by brain injury .

Can CBD Show Up in Drug Tests?

Derived from hemp, CBD is a legal substance under the United States Federal Law (61) . The United States 2018 Farm Bill legalized hemp extraction, making CBD legal in all 50 states and U.S. territories.

THC may show up in drug tests. In a full-spectrum CBD oil , the THC content must not exceed 0.3%. Even with the very low concentrations, there may be a chance that THC may show in drug tests.

Individuals are advised not to take full-spectrum CBD oil if their occupation requires them to take routine drug tests. They may opt for broad-spectrum CBD oil instead.

Conclusion

Many studies acknowledged CBD ‘s therapeutic effects and how it might improve brain health.

A study mentioned that CBD had been found to improve memory and cognitive performances (62) . It also demonstrated neurogenesis (forming of new nerve cells) and neuroprotective properties (63) .

Moreover, some studies have shown CBD’s potential benefits of reducing sleep disorders (64) , neuroinflammation (65) , and anxiety (66) .

The FDA has already acknowledged CBD ’s potential in treating neurological disorders by approving the first CBD drug for epilepsy. However, the total acceptance of CBD in the medical field remains to be seen.

A 2018 study mentioned that regulatory agencies may eventually approve CBD as a form of treatment. However, a careful study of safety, quality, and efficacy is still needed (67) .

Individuals are advised to consult a physician before adding CBD to their daily regimen.

  1. Maroon, J., & Bost, J. (2018). Review of the neurological benefits of phytocannabinoids . Surgical neurology international , 9 , 91. https://doi.org/10.4103/sni.sni_45_18
  2. Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente journal, 23, 18–041. https://doi.org/10.7812/TPP/18-041 .
  3. Watt, G., & Karl, T. (2017). In vivo Evidence for Therapeutic Properties of Cannabidiol ( CBD ) for Alzheimer’s Disease . Frontiers in pharmacology , 8 , 20. https://doi.org/10.3389/fphar.2017.00020
  4. Peprah K, McCormack S. Medical Cannabis for the Treatment of Dementia: A Review of Clinical Effectiveness and Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Jul 17. Available from: https://www.ncbi.nlm. nih .gov/books/NBK546328/
  5. Maroon, J., & Bost, J. (2018), Op cit.
  6. Cassano, T., Villani, R., Pace, L., Carbone, A., Bukke, V. N., Orkisz, S., Avolio, C., & Serviddio, G. (2020). From Cannabis sativa to Cannabidiol : Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases. Frontiers in pharmacology , 11 , 124. https://doi.org/10.3389/fphar.2020.00124
  7. Solowij, N., Broyd, S. J., Beale, C., Prick, J. A., Greenwood, L. M., van Hell, H., Suo, C., Galettis, P., Pai, N., Fu, S., Croft, R. J., Martin, J. H., & Yücel, M. (2018). Therapeutic Effects of Prolonged Cannabidiol Treatment on Psychological Symptoms and Cognitive Function in Regular Cannabis Users: A Pragmatic Open-Label Clinical Trial . Cannabis andcannabinoidresearch , 3 (1), 21–34. https://doi.org/10.1089/can.2017.0043
  8. Aso, E., Sánchez-Pla, A., Vegas-Lozano, E., Maldonado, R., & Ferrer, I. (2015). Cannabis-based medicine reduces multiple pathological processes in AβPP/PS1 mice. Journal ofAlzheimer’s disease: JAD , 43 (3), 977–991. https://doi.org/10.3233/JAD-141014
  9. Ibid
  10. Solowij, N., (2018). Op cit.
  11. Tang N. K. (2008). Insomnia Co-Occurring with Chronic Pain : Clinical Features, Interaction, Assessments and Possible Interventions. Reviews in pain , 2 (1), 2–7. https://doi.org/10.1177/204946370800200102
  12. Russo E. B. (2008). Cannabinoids in the management of difficult to treat pain. Therapeutics and clinical risk management, 4(1), 245–259. https://doi.org/10.2147/tcrm.s1928
  13. Babson, K. A., Sottile, J., & Morabito, D. (2017). Cannabis, Cannabinoids , and Sleep: a Review of the Literature. Current psychiatry reports , 19 (4), 23. https://doi.org/10.1007/s11920-017-0775-9
  14. Ibid
  15. Weatherall M. W. (2015). The diagnosis and treatment of chronic migraine. Therapeutic advances in chronic disease , 6 (3), 115–123. https://doi.org/10.1177/2040622315579627
  16. US Food and Drug Administration , The FDA Approves New Treatment for Adults With Migraine (2019). Retrieved from https://www. fda .gov/news-events/press-announcements/ fda -approves-new-treatment-adults-migraine
  17. Lochte, B. C., Beletsky, A., Samuel, N. K., & Grant, I. (2017). The Use of Cannabis for Headache Disorders. Cannabis andcannabinoidresearch , 2 (1), 61–71. https://doi.org/10.1089/can.2016.0033
  18. Leimuranta, P., Khiroug, L., & Giniatullin, R. (2018). Emerging Role of (Endo) Cannabinoids in Migraine. Frontiers in pharmacology , 9 , 420. https://doi.org/10.3389/fphar.2018.00420
  19. Ibid
  20. Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a Potential Treatment for Anxiety Disorders . Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 12(4), 825–836. https://doi.org/10.1007/s13311-015-0387-1
  21. Ibid
  22. Crippa, J. A., Guimarães, F. S., Campos, A. C., & Zuardi, A. W. (2018). Translational Investigation of the Therapeutic Potential of Cannabidiol ( CBD ): Toward a New Age. Frontiers in immunology , 9 , 2009. https://doi.org/10.3389/fimmu.2018.02009
  23. Ibid
  24. Leweke, F. M., Piomelli, D., Pahlisch, F., Muhl, D., Gerth, C. W., Hoyer, C., Klosterkötter, J., Hellmich, M., & Koethe, D. (2012). Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Translational psychiatry , 2 (3), e94. https://doi.org/10.1038/tp.2012.15
  25. Ibid , J., Sagredo , O., M. Ruth Pazos , García , G., Pertwee , R., Mechoulam , R., Martínez‐Orgado , J., (2012). Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid ? British Pharmacological Societyhttps://doi.org/10.1111/j.1365-2125.2012.04341.x
  26. Ibid
  27. Ibid
  28. U.S. Food and Drug Administration . FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy. Retrieved from https://www. fda .gov/news-events/press-announcements/ fda -approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms
  29. Silvestro, S., Mammana, S., Cavalli, E., Bramanti, P., & Mazzon, E. (2019). Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials . Molecules (Basel, Switzerland) , 24 (8), 1459. https://doi.org/10.3390/molecules24081459
  30. Pacher, P., Bátkai, S., & Kunos, G. (2006). The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacological reviews , 58 (3), 389–462. https://doi.org/10.1124/pr.58.3.2
  31. Ibid
  32. Mechoulam, R., & Parker, L. A. (2013). The endocannabinoid system and the brain. Annual review of psychology , 64 , 21–47. https://doi.org/10.1146/annurev-psych-113011-143739
  33. Pandey, R., Mousawy, K., Nagarkatti, M., & Nagarkatti, P. (2009). Endocannabinoids and immune regulation. Pharmacological research , 60 (2), 85–92. https://doi.org/10.1016/j.phrs.2009.03.019
  34. Pertwee R. G. (2008). The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids : delta9- tetrahydrocannabinol , cannabidiol and delta9-tetrahydrocannabivarin. British journal of pharmacology , 153 (2), 199–215. https://doi.org/10.1038/sj.bjp.0707442
  35. Blessing, (2015), Op cit.
  36. Solowij, N., (2018), Op cit.
  37. Aso, E., (2015), Op cit.
  38. Babson, K. A., (2017), Op cit.
  39. Russo E. B. (2008), Op cit.
  40. Leimuranta, P., (2018), Op cit.
  41. Blessing, (2015), Op cit.
  42. Leweke, F. M., (2012), Op cit.
  43. Crippa, J. A., (2018), Op cit.
  44. WHO. Expert Committee on Drug Dependence. (2017, Nov 6-10). Cannabidiol ( CBD ). Retrieved from https://www.who.int/medicines/access/controlled-substances/5.2_ CBD .pdf .
  45. The 2018 United States Farm Bill. Retrieved from https://www.usda.gov/farmbill
  46. Bauer, B. (2018, Dec 20). What are the benefits of CBD — and is it safe to use? Retrieved from https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is- cbd -safe-and-effective/faq-20446700
  47. InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Alzheimer’s disease : Do Ginkgo products help? 2009 Mar 10 [Updated 2017 Jun 29]. Available from: https://www.ncbi.nlm. nih .gov/books/NBK279357/
  48. Lopresti A. L. (2017). Salvia (Sage): A Review of its Potential Cognitive-Enhancing and Protective Effects. Drugs in R&D , 17 (1), 53–64. https://doi.org/10.1007/s40268-016-0157-5
  49. Lozano, I.,(2008), The Therapeutic Use of Cannabis sativa (L.) in Arabic Medicine. Journal of Cannabis Therapeutics.https://doi.org/10.1300/J175v01n01_05
  50. Dyall S. C. (2015). Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA. Frontiers in aging neuroscience, 7, 52. https://doi.org/10.3389/fnagi.2015.00052
  51. Calaway, J.C., Hempseed in a Nutshell., (2010)., Retrieved from https://www.google.com/url?q=https://www.aocs.org/stay-informed/inform-magazine/featured-articles/hempseed-oil-in-a-nutshell-march-2010?SSO%3DTrue&sa=D&ust=1595289444529000&usg=AFQjCNGR6eMTeP7H1D7xy3W6jPQIMNUnBw
  52. Aso, E.,(2015), Op cit.
  53. WHO, (2017, Nov 6-10), Op cit.
  54. Millar, S. A., Stone, N. L., Bellman, Z. D., Yates, A. S., England, T. J., & O’Sullivan, S. E. (2019). A systematic review of cannabidiol dosing in clinical populations. British journal of clinical pharmacology , 85 (9), 1888–1900. https://doi.org/10.1111/bcp.14038
  55. Shmerling, R.H., Can Vaping Damage Your Lungs? (2019)., Retrieved from https://www.health.harvard.edu/blog/can-vaping-damage-your-lungs-what-we-do-and-dont-know-2019090417734
  56. Ibid.
  57. Watt, G., & Karl, T. (2017). In vivo Evidence for Therapeutic Properties of Cannabidiol ( CBD ) for Alzheimer’s Disease . Frontiers in pharmacology , 8 , 20. https://doi.org/10.3389/fphar.2017.00020
  58. Peprah K, McCormack S. Medical Cannabis for the Treatment of Dementia: A Review of Clinical Effectiveness and Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Jul 17. Available from: https://www.ncbi.nlm. nih .gov/books/NBK546328/
  59. Schurman, L. D., & Lichtman, A. H. (2017). Endocannabinoids: A Promising Impact for Traumatic Brain Injury . Frontiers in pharmacology , 8 , 69. https://doi.org/10.3389/fphar.2017.00069
  60. The 2018 United States Farm Bill, Op cit.
  61. Solowij, N., (2018). Op cit. , (2012), Op cit.
  62. Babson, K. A., (2017), Op cit.
  63. Leimuranta, P., (2018). Op cit.
  64. Blessing, E. M., (2015). Op cit.
  65. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules (Basel, Switzerland) , 23 (10), 2478. https://doi.org/10.3390/molecules23102478

CBD Clinicals is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more