is entourage oil better for cbd

The Entourage Effect & CBD Oil – Is It A Game-Changer?

Thanks to a phenomenon known as the entourage effect, CBD oil and other CBD products appear to be more effective when in the presence of other natural hemp compounds, rather than by themselves.

If true, this would suggest that full-spectrum CBD products may be more beneficial compared to isolate or even broad-spectrum products. Full-spectrum products include a complete range of terpenes, cannabinoids, and other compounds found in hemp. Broad-spectrum products are similar, minus the presence of THC.

Of course, few reliable studies have been published relating to the entourage effect and its potential impact on humans using CBD products. In this article, we summarize what we know.

Read on to find out more.

What Is The Entourage Effect?

In basic terms, the entourage effect helps maximize the beneficial effects of CBD oil. It occurs when hundreds of different compounds in hemp interact with each other simultaneously to produce a synergistic physiological effect.

In 1998, doctors Raphael Mechoulam and Shimon Ben-Shabat were the first to suggest that the endocannabinoid system (ECS) demonstrated an ‘entourage effect.’ According to the Israeli researchers, various inactive metabolites and related molecules appeared to boost the activity of primary endogenous cannabinoids in the human body (namely 2-AG and anandamide).

In simpler terms, the entourage effect basically suggests that CBD is not solely responsible for the beneficial effects it produces in the body. The presence of other cannabinoids – such as CBN and CBDV – as well as terpenes like myrcene and beta-caryophyllene, appear to “amplify” the activity of CBD and its influence on various physiological systems.

Many suggest that terpenes, in particular, have a far more impactful presence in hemp extract than previously imagined. Terpenes are genuinely fascinating, not least because we’re still finding out how much they can help us. You can find terpenes everywhere, from the skin of citrus fruits to the essential oils squeezed from plant seeds.

Aside from smelling great, terpenes appear to help CBD function in the most efficient way possible. Think of it like a car; you could hypothetically drive down the road with a flat tire, a busted windshield, and a leaking radiator, but it would be a lot more efficient — and effective — if all those parts were functioning properly and working together.

What Does CBD Have To Do With The Entourage Effect?

Some people are incorrectly referring to this phenomenon as the “CBD entourage effect.” Indeed, CBD plays a tremendous role in the synergistic effects produced by dozens of hemp compounds working together and interacting with one another. However, it is inaccurate to label it as the most important part of the process.

In fact, no single hemp component should be labeled as the most important aspect of the entourage effect. All the “working internal parts” of hemp play a role; even if a single phytochemical component is missing, the cumulative effect may be diminished.

That being said – and going back to the car analogy – some hemp components do likely play more influential roles in terms of doing what the car is designed to do – which is get down the road as efficiently as possible.

In this analogy, CBD would almost certainly be the engine of the car; without it, the car’s not going anywhere. So, while it’s incorrect to label the entourage effect as the “CBD entourage effect,” there’s no denying that CBD plays a massive role in the whole synergistic process.

An “Entourage” of CBD Products…

So what’s a potential CBD user to make of all this information? It seems that with each passing day, there’s a greater entourage of CBD oil products out there on the market to choose from. How do you know which one’s best for you?

Well, it goes without saying that any quality CBD oil product needs to start out with quality hemp. At Premium Jane, we source all of our hemp from farms right here in the USA. We also only use non-GMO.

Why? Because we believe the safety and effectiveness of the end product can only ever be as high as the quality of the starting plant material. In other words, only the purest, highest quality plants can produce the purest, highest quality CBD oil products. It’s really as simple as that.

What Else Should I Know About CBD Oil & The Entourage Effect?

In order to take full advantage of the entourage effect, CBD oil would need to be consumed in the form of a full-spectrum hemp extract (FSE). In the most basic sense, full-spectrum products contain a complete range of hemp’s natural phytochemicals — including small amounts of THC at levels of 0.3% or less.

Of course, FSE products are not the best option for every single user out there. For example, for folks that want to avoid consuming THC altogether, a broad-spectrum product or even a CBD isolate product would be a better option.

Broad-spectrum CBD products are very similar to full-spectrum products. The only difference is that broad-spectrum products are 100% THC-free. CBD isolate products, of course, contain CBD and nothing else.

At Premium Jane, we understand that the needs of our customers vary. This is why we offer two major types of CBD products: full-spectrum and CBD isolate. If you’re looking for the market’s most expertly-crafted range of authentic hemp-derived products, there’s really no better option than the USA-made Premium Jane range.

The Bottom Line On The Entourage Effect & CBD Products

According to the phenomenon of the entourage effect, CBD is most effective when in the presence of other natural hemp phytocompounds. In other words, it appears that cannabinoids (including CBD) are influenced by the presence of compounds like terpenes, flavonoids, and possibly even nutritional components like hemp-derived omega acids.

Both full and broad-spectrum CBD products contain a variety of hemp compounds. Hemp CBD isolates, on the other hand, contain nothing except for the isolated CBD compound. Depending on a user’s personal needs, one type of CBD product may be preferred over another. Those looking to take advantage of the entourage effect, for example, will want to opt for a premium full or broad-spectrum CBD product. Those who want to avoid consuming any quantity of THC, on the other hand, may find that a CBD isolate product is the preferred option.

The Entourage Effect and CBD: What Does It Mean?

CBD has the potential to unlock several health and wellness benefits, but it does its best work in combination with other compounds found in the Cannabis plant.

The Entourage Effect Explained

The entourage effect:

  • is the theory that all compounds in cannabis work together, and when taken in combination, they produce a better effect than when taken alone.

The hemp plant:

  • contains more than 100 different compounds called cannabinoids and terpenes that can interact with your endocannabinoid system

Your endocannabinoid system:

  • works to keep your body in homeostasis, or balance.
  • Its purposes range from neuroprotection to regulation of your immune system, impacting things like appetite, sleep, mood, and pain.
Related post: How CBD Works With Your Body For Natural Relief

CBD & THC are the 2 most popular cannabinoids. Other cannabinoids like CBN, CBC, CBA, CBG, and THC and terpenes such as myrcene, pinene, limonene, and caryophyllene, are also naturally present in cannabis and play a supportive role.

Research has shown that taking a precise, balanced formulation of these cannabinoids and terpenes is more effective than taking even the highest quality CBD or THC alone. This is due to an interaction between the cannabinoids and terpenes called “the entourage effect.”

What does the Entourage Effect Mean For CBD Consumers?

In the world of CBD products, this means that in order to experience optimal health benefits you will want to find full-spectrum CBD products. If you can’t take THC, look for broad-spectrum CBD products. CBD Isolate will not provide the same effects, as it contains only the CBD cannabinoid.

This also means that you’ll want to buy from a trusted manufacturer who balances their products with a scientifically-based amount of cannabinoids, flavonoids and terpenes. There are many manufacturers of CBD products who have no idea how much of each cannabinoid are in their product, and you’ll find the effects will vary with each purpose. This is because it isn’t balanced or consistent.

Simply put – The Entourage Effect means that CBD works better in combination with other cannabinoids and terpenes found in the hemp plant (including some THC), than when isolated. As a consumer, you will want to use full-spectrum CBD products for maximum benefits. If you can’t take THC, look for broad-spectrum CBD products.

Try Redeem’s pharmaceutical-grade CBD products

What’s the Difference in CBD Products: CBD Isolate, Broad-Spectrum, Full-Spectrum and Optimal Spectrum?

There are several different types of CBD products on the market that contain different compounds of the plant – CBD Isolate, Broad-Spectrum, Full-Spectrum & Optimal-Spectrum. These terms are basically referring to the makeup of the team, the synergy of the players that surround the CBD in the product.

  • CBD Isolate contains no terpenes or cannabinoids other than CBD, removing potential benefits associated with the entourage effect. contains a combination of cannabinoids and terpenes but has all traces of THC removed. It still harnesses some of this synergistic power, although the entourage effect may be reduced because these CBD products have all traces of THC removed.
  • Full-spectrum is packed with cannabinoids like CBD, terpenes, and trace amounts of THC–less than the national legal limit of 0.3%–to maximize your unique benefits through the entourage effect.
  • Optimal-Spectrum CBD contains a precise, balanced formula of all cannabinoids and terpenes found in the hemp plant that has been shown to have the optimal entourage effect, and is Redeem Therapeutic’s promise to consumers

Some CBD products may also highlight other cannabinoids or terpenes they’ve added into their mix to increase it’s effects for a specific purpose, like our special Sleep Formula with CBD and CBN. Although every company is unique, the main differences from one CBD product to another are the cannabinoids and terpenes included and how those compounds work together.

But don’t let the labeling fool you. Just because a product says it is broad-spectrum or full-spectrum CBD doesn’t mean that it’s quality. This is why we introduced our Optimal-Spectrum CBD promise for quality and consistency.

Related Post: Understanding Optimal-Spectrum CBD

The Redeem™ Promise

Grown by Nature, Perfect by Science. We Are Redeem Therapeutics.

The number and concentrations of cannabinoids and terpenes in full-spectrum products offered by most CBD companies is not standardized. The mix of cannabinoids and terpenes differs in each cannabis plant with each grow season, from farm to farm, in different locations within a field, and with inconsistencies in the processing methods. Due to this variability, CBD consumers may buy the same product over and over again and experience varying beneficial effects with every new purchase. The product and processes are not optimized.

Redeem offers Optimal Spectrum™ CBD tinctures with formulations based on our extensive research. Yes, our products are Full-Spectrum, but they have been optimized to ensure that the spectrum remains consistent from batch to batch. When the natural variation falls short, we redeem the solution of terpenes, flavonoids and cannabinoids for a consistent product every time. That’s the Redeem Promise.

Redeem™ bridges the gap between natural alternatives and pharmaceutical precision. Our unique perspective is formed by the scientific discipline of more than 60 years in the pharmaceutical industry. We offer Full-Spectrum and Broad-Spectrum CBD Products. All Redeem™ CBD products are made from 100% organic hemp & Crafted in the Carolinas. The Redeem™ team adheres to cGMP (Good Manufacturing Practice) and 3rd party testing so that you’ll never have to wonder about the quality of what’s in your bottle.

We used cGMP compliant processes and test each lot of product for key cannabinoids and terpenes. Then, we add back any compound that is below our minimum specification. If our product works for you today, it will work the same with each subsequent purchase.

Want to try the Redeem™ difference? Shop our Optimal Spectrum CBD Products online today.

The Entourage Effect Defined

The “entourage effect” is defined as the synergistic relationship between CBD and the other naturally occurring compound. It means that all cannabinoids and terpenes found in the Cannabis plant work together for optimal benefits, and that CBD isolated by itself will be less effective that when used in combination with other cannabinoids and terpenes.

The term “entourage effect” was first coined in 1998 by Dr. Ben-Shabat in his paper, An Entourage Effect: Inactive Endogenous Fatty Acid Glycerol Esters Enhance 2-Arachidonoyl-Glycerol Cannabinoid Activity . The concept has most notably been explained and expanded upon by Dr. Etahan Russo in his 2011 peer-reviewed article entitled, Taming THC: Potential Cannabis Synergy and Phytocannabinoid-Terpenoid Entourage Effects . In his article, Dr. Russo summarizes the results of dozens of research papers concerning medicinal uses of cannabis and the evident synergies between the various cannabinoids and terpenes found in Cannabis sativa.

One particular animal study published in the Journal of Pharmacology and Pharmacy in 2015 showed that CBD alone demonstrated a bell-shaped dose response in the treatment of inflammation-induced pain. The bell-shaped or biphasic dose response refers to the fact that increasing the dose of pure CBD without other cannabinoids or terpenes results in pain relief up to a point but actually showed reduced effectiveness once that dose was exceeded. However, increasing the dose of CBD that is combined with other cannabinoids and terpenes evidenced a consistent, more linear, increase in effectiveness.

The bottom line? CBD is more effective and predictable with its entourage. Synergy matters.

With this newfound knowledge on the entourage effect, you can maximize your CBD benefits with products that include all of your favorite compounds. Find your new favorite CBD product with Redeem Therapeutics!

At Redeem, we are only satisfied with the best, which is why we make sure all of our Optimal Spectrum CBD tinctures present the ideal amounts of CBD and terpenes in our balanced formula. Whether you’re enjoying our easy-to-use CBD tincture sprays, our CBD topical pain cream, or our paws-itively amazing CBD oil for dogs and cats, you can be confident you are using high-quality, organically grown CBD.

CBD & The Entourage Effect – The Ultimate Guide

As a CBD consumer, what do you need to know about the entourage effect? Is this scientific theory something that you need to consider when picking the next CBD product to add to your daily wellness routine? The entourage effect is often shrouded in mystery and we’ve been noticing that there is a general lack of understanding around what this theory is and why it’s important.

We believe that education is the key to encouraging more people to incorporate CBD products into their daily wellness routine. In this article, we are going to be holding a magnifying glass to the theory of the entourage effect. We will be giving you crucial insights into everything that you need to know about the entourage effect.

With a back-to-basics approach, we will be looking specifically at these commonly asked questions relating to CBD and the entourage effect:

What is CBD?

How does CBD oil make you feel?

Can CBD oil get you high?

Does the human body have a cannabinoid system?

Do all humans have cannabinoid receptors?

What does CBD do to you?

Will CBD show on a drug test?

How often should I take CBD oil?

Can you take too much CBD?

What is the entourage effect?

How does the entourage effect work?

What does the entourage effect feel like?

Is full spectrum CBD better?

Does broad-spectrum CBD get you high?

After reading this article, we are confident that you will have a solid understanding of what the entourage effect is, why it could benefit you, and how it could influence your future buying decisions. We wanted to make this article as accessible as possible for those that are new to the world of CBD. So, let’s start at the very beginning…

What is CBD?

CBD is just one of many cannabinoids found in the cannabis plant. Cannabinoids are a group of chemical compounds that collectively represent the many different characteristics of cannabis. CBD and THC are perhaps the most widely recognized of all the cannabinoids. Despite having the same molecular structure, these two chemical compounds could not be more different in terms of how they interact with cannabinoid receptors in the body.

THC is the main psychoactive component of the cannabis plant. This is directly responsible for the “high” sensation that many people are left with after smoking cannabis. CBD is also psychoactive but it is non-intoxicating and won’t result in a “high” sensation, no matter how much of it you consume. Instead, whilst THC can alter your state of mind, CBD focuses on providing potentially therapeutic effects.

CBD products have been taking the wellness industry by storm. This cannabis-derived chemical compound has been incorporated into a full range of different products that can be used for everyday wellbeing. From oils and topicals to beverages and edibles, there’s a wide variety of CBD products available to choose from with their own unique methods of consumption. The sheer level of consumer choice and flexibility has helped make CBD products accessible to everyone.

How does CBD oil make you feel?

CBD oil is one of the most popular products in the CBD marketplace. In the space of just a few years, it has emerged in popular culture as a go-to wellness product for those that are looking for a food supplement to support their overall wellbeing. It’s important to remember that CBD products, including CBD oil, are sold as food supplements. They are not intended to be used for medicinal purposes, despite the rather exciting therapeutic benefits of this compound.

CBD oil can make you feel calm and relaxed alongside a range of other benefits. Extensive research into the effects of CBD oil has shown that it has the potential to support the reduction of unnecessary inflammation in the body. The way in which CBD interacts with cannabinoid receptors, located throughout the body, enables it to influence human physiology in a number of ways, regulating things such as sleep, mood, and appetite.

CBD oil is to be consumed through sublingual administration. This is where you place a few drops of the oil under your tongue. You should hold these drops under your tongue for up to 30 seconds. This gives the oil enough time to diffuse into your bloodstream through the tissues in your tongue. CBD is only effective when it enters the bloodstream. The more CBD you can get into the bloodstream, the more effective it is likely to be.

Sublingual administration is seen as being the most efficient way to introduce CBD into your body. It all comes down to the route in which CBD takes to enter the bloodstream. If you give CBD a shorter route into your bloodstream, you will inevitably lose less CBD along the way. If you’re looking for value for money and you want to get the most out of this chemical compound, CBD oil is the ideal product for you.

Can CBD oil get you high?

As we said earlier, consuming CBD in an isolated form cannot result in a “high” sensation. CBD can often contain trace amounts of THC but this is not enough to present any noticeable effects. At Spero CBD, all of our CBD products are THC-free due to our rigorous testing process. Taking products like CBD oil, as part of your daily wellness routine, will not create this sensation.

In comparison to THC, the overall effects of CBD on the human body are much more subtle, placing an emphasis on wellbeing and instilling a sense of calm in the franticness of modern life. If you’re looking for a product that will get you “high,” CBD oil is not for you. However, if you need a product to support your day-to-day wellbeing, you need to consider CBD oil.

Does the human body have a cannabinoid system?

Yes – every human body has an endocannabinoid system that plays an essential role in supporting the physiological systems that must be maintained for health. The endocannabinoid system has a singular mission: to bring a sense of balance to the human body by regulating many of its core functions and ensuring that everything is working in harmony.

The role of the endocannabinoid system is to create this equilibrium. The human body is at its very best when everything is working in unison. In other words, this system is designed to promote homeostasis, keeping your body functioning optimally regardless of any challenges that it may face from external forces. A strong ECS will support the performance of your core functional processes whatever the weather!

Do all humans have cannabinoid receptors?

The cell-signaling system consists of neurotransmitters, receptors, and enzymes. These three components help the system to promote homeostasis throughout the body. Principally, there are two main types of receptors: CB1 and CB2 receptors. CB1 receptors are found in the brain (central nervous system) and elsewhere in the body, whilst CB2 receptors are typically located in the gastrointestinal and immune systems (periphery). There are usually far fewer CB2 receptors than CB1 receptors in the body.

The vast majority of cannabinoids can bind to both CB1 and CB2 receptors. As humans, we naturally produce cannabinoids in our bodies. These are known more specifically as endocannabinoids, stemming from the word “endogenous.” When you consume a cannabinoid through the use of a product like CBD oil, these are called exogenous cannabinoids because they come from external sources, such as the cannabis plant.

Whilst everyone has an endocannabinoid system, some of us have stronger systems than others. This is because many people are enhancing the power and capability of their endocannabinoid system with exogenous cannabinoids. Products like CBD oil is an example of this. CBD is a plant-based cannabinoid that can help to support the ECS in its endeavours to promote homeostasis.

What does CBD do to you?

The therapeutic benefits of CBD can vary from person to person. Anecdotal evidence and scientific evidence has suggested that CBD can provide a sense of relief to those that are suffering from chronic pain, anxiety, and stress. There’s still so much about this cannabis-derived chemical compound that we don’t know. However, evidence is quickly mounting to show just how beneficial this cannabinoid can be to our everyday wellbeing.

Scientific research has found that CBD can have a tremendous impact on the overall effectiveness of your endocannabinoid system, stimulating both CB1 and CB2 receptors. Although, unlike many other cannabinoids, CBD does not directly bind itself to either of the two receptors, having the unique ability to influence the ECS in a way that sets it apart from other exogenous cannabinoids.

Will CBD show on a drug test?

This is one of the most common questions that we get asked. It’s a completely reasonable question but the fact it keeps getting asked shows that the general public still have a very limited understanding of exactly what CBD is. Hopefully, with the assistance of educational articles like the one you’re reading now, you will increase your knowledge of CBD and use this to inform your buying decisions.

No – CBD is highly unlikely to show up on a drugs test. The assumption that CBD will show up on a drug test is tied to the false belief that this chemical compound will result in a “high” sensation when consumed. It’s incredibly important to understand that CBD is just one component of the cannabis plant. This does not automatically mean that it carries all of the same traits and characteristics as the whole plant.

At Spero CBD, our CBD products are entirely THC-free, so there is little to no chance of CBD showing up on a drugs test. Full spectrum CBD products have the potential to show up on a drugs test, as these contain all of the naturally occurring cannabinoids in the cannabis plant, including trace amounts of THC. Although, even then, we would be very surprised if full spectrum CBD showed up on a drugs test.

How often should I take CBD oil?

When you introduce a new food supplement like CBD oil to your body, you should aim to start with a small dosage before gradually increasing it. This will give you time to see how your body reacts to the cannabinoid before consuming a large amount. You should always follow the instructions that come with each individual CBD product. It’s important to do this as some CBD products have different strengths and contain higher percentages of CBD than others.

Can you take too much CBD?

Experiencing adverse effects to CBD is incredibly rare but you should try your best to monitor the amount of CBD that you are taking on a regular basis. It isn’t possible to overdose on CBD, but if you take too much at one time, you could experience some very minor side effects, such as dizziness. As time goes on and you begin to learn more about how your body responds to certain CBD products, you will be able to find an optimal dosage.

Some people can get all of the therapeutic benefits they need from a very small dosage of CBD oil, whereas others require a much larger dosage to experience the same effects. It’s all about finding a dosage that works for you and this will come with experience taking the cannabinoid. You might find that certain CBD products, like CBD oil, have the ability to provide you with greater levels of therapeutic value than other products on the market.

What is the entourage effect?

The entourage effect is a theory that could completely change how you decide to consume CBD going forward. The theory proposes the idea that CBD is more effective when it is ingested with other cannabinoids at the same time. When you purchase standard CBD oil, you are buying the compound in an isolated form with no other cannabinoids attached. Using the whole hemp plant, full spectrum CBD contains all of the naturally occurring cannabinoids in the cannabis plant, along with trace amounts of THC.

How does the entourage effect work?

There is much more to cannabis than just CBD and THC. The plant contains dozens of different cannabinoids that each have their own unique properties. CBD may be the most beneficial from a wellness standpoint, but the support of other cannabinoids can actually boost the performance of the compound and its ability to positively impact the ECS. This is why many people have been turning to full spectrum CBD as part of their daily wellness routine.

The diverse cannabinoid content in full spectrum CBD can help to maximize the possibilities of the cannabis plant as it enters your body. If you are an experienced user of CBD isolate and want to start exploring more cannabinoids in the cannabis plant, you could give full spectrum CBD oil a try to see whether the entourage effect manifests itself.

What does the entourage effect feel like?

While CBD interacts with CB1 and CB2 receptors, it does not bind to them. This is rather unusual among cannabinoids. By using full spectrum or broad spectrum CBD oil, you will be consuming a range of cannabinoids that bind to receptors located in both the central nervous system and the peripheral nervous system. You can think of the entourage effect as the enhancement of your endocannabinoid system through the use of multiple cannabinoids.

Is full spectrum CBD better?

It all depends on what you’re looking for! Some people prefer CBD isolate over full spectrum CBD because of the entourage effect. For more advanced users of CBD, consuming this cannabinoid in an isolated form is going to offer limited therapeutic effects. Whereas full spectrum CBD is going to drastically enhance those effects and unlock the keys to a whole world of new exogenous cannabinoids that have never entered your system before.

If you’re a CBD beginner, trying full spectrum CBD has the potential to overwhelm you. CBD in an isolated form can serve as the perfect introduction to the chemical compound with subtle effects that you will be able to easily monitor. When you’ve never had a CBD product before, buying full spectrum CBD is like jumping into the deep end.

Does broad-spectrum CBD get you high?

Neither broad-spectrum CBD or full spectrum CBD can result in a “high” sensation. It can be very easy to confuse the different CBD products on the marketplace. CBD isolate only contains CBD. Full spectrum CBD contains all of the naturally occurring cannabinoids found in the cannabis plant, along with trace amounts of CBD. Broad-spectrum CBD contains all of the compounds found in the cannabis plant, including terpenes, cannabinoids, and essential oils, with the exception of THC.

Final Thoughts

We hope that this article has proven to be a useful educational resource as you endeavour to learn more about the incredible world of CBD. Understanding the content of the entourage effect is vital to be able to distinguish between different forms of CBD. If you know exactly what you’re buying, you will inevitably make stronger buying decisions that are going to provide you with greater levels of benefit.