topical cbd oil for cancer

Now that Weed Is Becoming Legalized, Should More People with Cancer Use Cannabis?

You and your MSK care team should make a joint decision on using cannabis.

New York State is the latest to legalize the recreational use of marijuana for adults.

We asked Nirupa Raghunathan, an integrative medicine doctor at Memorial Sloan Kettering, and pharmacist Jason Hou, who manages MSK’s About Herbs database, to share what people with cancer should know before trying marijuana or its cousin, cannabidiol (CBD).

What does the new law mean for adults in New York?

Dr. Raghunathan: The new law allows New Yorkers 21 and over to have up to three ounces of marijuana for recreational use. Using and selling marijuana are both legal, except in schools, workplaces, or in cars. The law also allows New Yorkers up to 24 grams of concentrated cannabis products, including products containing CBD, which is one of many chemicals extracted from the cannabis plant. CBD is different from delta-9-tetrahydrocannabinol, also known as THC, which is another chemical extracted from the cannabis plant.

The law also establishes retail licenses, opening the door for dispensaries selling marijuana online and in retail stores.

Should people with cancer consider using marijuana for anxiety or to ease side effects from treatment?

Dr. Raghunathan: While legalization and regulation may change the accessibility and/or quality of all cannabis products, it doesn’t change the lack of scientific evidence. Unfortunately, we still don’t know enough about the benefits of these products for people with cancer. There is a lot of research happening in Canada and Australia because regulations around its use there have changed. It will be interesting to see what comes out of that. In the meantime, you and your doctor should discuss the potential benefits and harms of using anything with cannabis for medical purposes.

What about medical marijuana? How is it different from recreational marijuana and how can patients get it?

Dr. Raghunathan: Medical marijuana contains THC and that requires certification in states that allow for medical marijuana. In New York, people with cancer are allowed to use medical marijuana in the form of capsules, liquids, oils, powder, and patches for the skin. There is medical cannabis that can be vaped, but not medical-grade marijuana leaf that can be smoked. Medical marijuana providers must be registered with the New York State Department of Health’s Medical Marijuana Program. The restrictions in New York state are changing, but we don’t know how just yet.

Cannabis, also known as marijuana, is used to treat some symptoms related to cancer. It’s made from the flowers, leaves, and resin (sticky chemical) of the Cannabis sativa plant.

How can people with cancer use CBD?

Dr. Raghunathan: It is possible that CBD could have a benefit with symptoms of anxiety, poor sleep, and pain. CBD has been studied a lot in the laboratory and in mice but far less in humans. Right now there are some studies that are evaluating CBD as a part of cancer treatment, but none of those have had significant results. The studies that do show a benefit with CBD are for specific epilepsy syndromes in children.

What do we know about how CBD works?

Dr. Hou: When CBD is taken by mouth, some amount is absorbed and becomes available in the blood. There are cannabinoid receptors throughout the human body, and when CBD binds to them, that can trigger biological effects. But the downstream effects are still unclear because currently, there are very few human data. Other edible products containing CBD are likely absorbed and metabolized in a similar manner. There is, however, limited absorption through the skin with topical CBD oil.

Dr. Raghunathan: How CBD works is not fully understood, but it seems to work through a variety of pathways in the body that have different effects. For example, it seems to have an anti-inflammatory effect, which is helpful with pain. It also works on serotonin receptors, which helps with anxiety. Because CBD works in many ways, people should discuss it with a doctor. It is important to understand both the possible benefits and risks.

Dr. Hou: We need more research to assess the safety and effects of CBD. And we need to take a closer look at potential herb-drug interactions, which is especially important for people receiving chemotherapy.

Does CBD have psychoactive properties, like marijuana? Is it a sedative?

Dr. Raghunathan: CBD is not psychoactive in the same way that marijuana is. It doesn’t act on the cannabinoid receptors in the central nervous system, which is how THC works. However, it is possibly psychoactive because it works on serotonin receptors, and anything that affects mood is psychoactive. CBD has been studied in mice and seems to affect sleep-wake cycles. But CBD can be unexpectedly psychoactive and sedative because it’s not well-regulated. Studies have shown that some products that claim to be pure CBD actually have THC and other dangerous contaminants, such as opioids.

Dr. Hou: Since everyone responds to oral CBD differently, the side effects may range from mild sedation to cannabinoid hyperemesis syndrome. This is characterized by repeated and severe bouts of vomiting.

Best CBD Oil for Cancer

Are you or is someone you know undergoing cancer treatments ? We at CBD Clinicals have gathered the top cannabidiol (CBD) products and the best CBD oils to help you regulate your cancer symptoms and maintain overall wellness .

Spruce 750mg Lab Grade CBD Oil
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

View Latest Prices

Mid-strength
Natural peppermint flavor
Made from 100% organic and natural ingredients
No other flavors
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

View Latest Prices

Pure CBD hemp
All natural
Approximately 300 drops total
No other flavors
Spruce 2400mg Lab Grade CBD Oil
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

View Latest Prices

Extra Strength
No artificial flavoring or colors
Made from 100% organic and natural ingredients
Tastes bitter
No THC-free option
Avida Full Spectrum CBD Oil Tincture 500mg
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

View Latest Prices

Light Spearmint flavor
Non-THC, Non-detected in drug test
No other flavor

Best Natural Alternative

cbdMD CBD Oil Tincture Natural 1500mg
  1. Made using only CBD sourced from medical hemp
  2. Available in many flavours
  3. Safe for daily use

View Latest Prices

Various delicious flavors to choose from
Has vegan, organic, and gluten-free ingredients
Free shipping for this particular product within USA
World-class customer service team
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
CBDistillery THC Free CBD Oil Tinctures
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

View Latest Prices

60-Day Satisfaction Guarantee
Various strengths
Oil extracted from aerial plant parts of US grown industrial hemp
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Dropper is a bit shaky

Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

View Latest Prices

Vegan and Gluten free
Has a third-party lab test
Wide variety of CBD strengths and sizes
Does not ship internationally
NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

View Latest Prices

Pure CBD hemp
All natural
Approximately 100 drops total
No other flavors
A bit pricey compared to competitors

Best Flavor Range

Hemp Bombs 750mg CBD Oil
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

View Latest Prices

Wide variety of flavors
Lab test results are complete
30-day money-back guarantee
Incomplete information about the product
Does not ship to all international countries

Best CBD Oil for Cancer 2022

    Editor's Pick Best Organic Editor's Pick Best Seller Best Natural Alternative Best THC-Free Best Customer Rated Best Starter Best Flavor Range

Compare the Best CBD Oil for Cancer in 2021

Best CBD Oil for Cancer

1. Spruce 750mg Lab Grade CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Mid-strength No other flavors
Natural peppermint flavor
Made from 100% organic and natural ingredients
Pros
Mid-strength
Natural peppermint flavor
Made from 100% organic and natural ingredients
Cons
No other flavors
Overview

Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Pure CBD hemp No other flavors
All natural
Approximately 300 drops total
Pros
Pure CBD hemp
All natural
Approximately 300 drops total
Cons
No other flavors
Overview

Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Extra Strength Tastes bitter
No artificial flavoring or colors No THC-free option
Made from 100% organic and natural ingredients
Pros
Extra Strength
No artificial flavoring or colors
Made from 100% organic and natural ingredients
Cons
Tastes bitter
No THC-free option
Overview

The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Light Spearmint flavor No other flavor
Non-THC, Non-detected in drug test
Pros
Light Spearmint flavor
Non-THC, Non-detected in drug test
Cons
No other flavor
Overview

Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Various delicious flavors to choose from cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Has vegan, organic, and gluten-free ingredients
Free shipping for this particular product within USA
World-class customer service team
Pros
Various delicious flavors to choose from
Has vegan, organic, and gluten-free ingredients
Free shipping for this particular product within USA
World-class customer service team
Cons
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Overview

cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
60-Day Satisfaction Guarantee Dropper is a bit shaky
Various strengths
Oil extracted from aerial plant parts of US grown industrial hemp
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Pros
60-Day Satisfaction Guarantee
Various strengths
Oil extracted from aerial plant parts of US grown industrial hemp
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
Cons
Dropper is a bit shaky
Overview

CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Pure CBD hemp No other flavors
All natural A bit pricey compared to competitors
Approximately 100 drops total
Pros
Pure CBD hemp
All natural
Approximately 100 drops total
Cons
No other flavors
A bit pricey compared to competitors
Overview

This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Vegan and Gluten free Does not ship internationally
Has a third-party lab test
Wide variety of CBD strengths and sizes
Pros
Vegan and Gluten free
Has a third-party lab test
Wide variety of CBD strengths and sizes
Cons
Does not ship internationally
Overview

A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Pros Cons
Wide variety of flavors Incomplete information about the product
Lab test results are complete Does not ship to all international countries
30-day money-back guarantee
Pros
Wide variety of flavors
Lab test results are complete
30-day money-back guarantee
Cons
Incomplete information about the product
Does not ship to all international countries
Overview

Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

How We Rank
Our Ratings

How CBD Helps With Cancer

Cancer comes in different forms and involves many types of treatment, including surgery, radiation therapy, chemotherapy, hormone therapy, stem cell transplant, immunotherapy, targeted therapy, and precision medicine (1 ) .

According to the National Cancer Institute, side effects of cancer treatment , particularly chemotherapy, may include fatigue, loss of appetite, nausea, diarrhea, mouth sores, hair loss, and anemia ( 2 ) .

A 2011 research study in the British Journal of Pharmacology suggested that CBD ha d antiemetic ( vomit-preventing ) properties and may help reduce nausea and vomiting induced by chemotherapy ( 3 ) .

CBD interacts with the endocannabinoid system (ECS), which regulates the body’s homeostasis or biological balance in response to environmental changes ( 4 ) . The ECS also affects cell growth and apoptosis (cell destructio n necessary for growth).

The ECS maintains physiological function, including chronic pain perception, mood, and cognition. Experts believe that the system can modulate these functions through its cannabinoid receptors ( 5 ) .

CB1 and CB2 are the primary types of receptors with unique roles in the ECS. These receptors exist in specific parts of the human body and may help with treating different cancer cells in various body parts.

CB1 receptors are prevalent in t he brain and the central nervous system. They are also located in the retina, lungs, liver, reproductive organs, and gastrointestinal and urinary tracts ( 6 ) .

CB1 receptors affect motor regulation, memory processing, pain management, appetite, sleep, and mood ( 7 ) .

Experts link the activation of CB1 receptors to neuroprotective responses, suggesting that cannabinoids with a greater affinity for CB1 receptors may help with neurodegenerative conditions.

Neurodegenerative diseases occur when there are miscommunications between brain cells, result ing in neuron death. Among these neurodegenerative conditions are Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.

Meanwhile, CB2 receptors primarily exist in immune system cells and their associated structures.

Triggering CB2 receptors stimulates a response that fights inflammation, reduces pain, and minimizes tissue damage.

Anti-inflammatory responses like these may help treat conditions linked to inflammation, including arthritis, Crohn’s disease, chronic inflammatory demyelinating polyneuropathy (CIDP), and inflammatory bowel syndrome (8 ) .

A placebo -controlled study in the Journal of Pain and Symptom Management showed that THC :CBD extract was effective for pain relief among patients with advanced cancer pain not fully relieved by potent opioids ( 9 ) .

Tetrahydrocannabinol, or THC, is a cannabinoid that causes users to experience a high.

How to Use CBD Oils and Tinctures for Cancer

For cancer, you may take CBD in edible forms. These consumable formats include CBD gummies , CBD brownies, and CBD capsules. This method of consuming CBD is suitable for beginners, as it is more straightforward than other methods.

The sublingual method is another way to administer CBD suitable for a more controlled CBD intake. With this option, you take the calibrated dropper included in most CBD tincture products and put a few drops of CBD oil tincture under your tongue.

Leave the oil under the tongue for about two minutes before swallowing. This holding period allows your mucous membranes to absorb the tincture.

Meanwhile, you may also inhale CBD through flavored or unflavored vaping products. This method is ideal for choosing peppermint or fruity flavors over the natural, earthy flavor of pure CBD oil .

Vaping also brings CBD in to your system quickly through the lungs. However, note that CBD vapes may affect lung cancer or lung disorders ( 10 ) .

As such, first – time users of CBD for cancer should seek medical advice from a licensed physician. When purchasing CBD products , you should get advice from a doctor with significant experience in CBD and cannabis oil product usage.

How Soon Does It Take to Feel CBD’s Effects on Cancer?

Depending on how you use a CBD product for cancer and its symptoms, the time it takes for CBD to work may vary.

Taking CBD by Mouth

Oral administration of CBD involves ingestion in the form of food, drink s , gummies , or capsules. For beginners, these are more straightforward ways to take CBD oil .

Through sublingual administration, you can absorb CBD directly into your bloodstream.

You might find CBD oil ’s natural flavor unpleasant through sublingual administration. However, the effects of CBD oil generally last for 4 to 6 hours, which you may be able to feel within 15 to 45 minutes ( 11 ) .

CBD oil tinctures or drops are your practical option if you prefer quick results and maximum dosage control.

Topical CBD Application

CBD topicals , such as CBD transdermal patches and CBD creams, work instantly after rubbing the product onto the affected area. This method may help relieve the painful side effects of cancer.

You may opt to apply topical CBD oil alone or combine the product with cream s or lotion s ( 12 ) . Using CBD topicals or other CBD-infused creams with massage therapy may help you feel relief in about 15 minutes ( 13 ) .

Applying CBD topically may result in CBD not interacting with the ECS as a whole. Instead, CBD topicals target localized clusters of cannabinoid receptors .

Note that determining whether the pain-relieving properties of a CBD topical product comes from CBD or another ingredient is difficult. Topical products may include other common over-the-counter pain-relief ingredients, such as menthol, camphor, or capsaicin.

Inhaling CBD

You can feel CBD’s purported effects within minutes when using a vape pen to inhale CBD vape juices. After inhalation, the effects may last between three to five hours ( 14 ) .

However, determining the precise amount of CBD you get from each draw of CBD vapes is challenging.

Still, inhaling CBD vapors may be the quickest way to get CBD into your body. Through inhalation, you allow CBD to enter your bloodstream through the lungs. As such, CBD does not go through your digestive system.

Note that the American Cancer Society Cancer Action Network (ACS CAN), the Society’s advocacy affiliate, opposes the vaping or smoking of medical marijuana and other cannabinoids in public places.

ACS CAN states that the carcinogens in marijuana smoke pose numerous health hazards to cancer patients and other people in the patient’s presence ( 15 ) . Carcinogens are substances that promote cancer formation.

What to Look for When Selecting a CBD Oil or Tincture for Cancer

Although CBD is not approved as a supplement for treating cancer according to the United States Food and Drug Administration ( FDA ) ( 16 ) , you may still choose from the three forms of CBD currently available on the market: full-spectrum CBD , broad-spectrum CBD, and CBD isolates.

Full-spectrum CBD oil contains all of the natural compounds present in Cannabis sativa plants, from flavonoids and terpenes to cannabinoids , including tetrahydrocannabinol ( THC ).

High – quality full-spectrum hemp extract contains a higher cannabidiol content than the other cannabis compounds.

CBD oil that contains all of cannabis ’ naturally occurring chemical compounds produce the entourage effect . This phenomenon involves the combination of all the cannabis plants ’ contents to produce synergistic effects in aiding anxiety disorders and mood disorders ( 17 ) . These conditions are common side effects among cancer patients .

To obtain full-spectrum CBD , manufacturers make industrial hemp plants undergo extraction methods, such as steam distillation, CO 2 extraction, or alcohol extraction. Manufacturers then mix the pure hemp oil with a carrier oil, such as hempseed oil or MCT oil.

Researchers of a 2018 study indicate that the FDA recognizes the Supercritical-CO 2 process as safe in pharmaceutical manufacturing ( 18 ) .

Like full-spectrum CBD , the broad-spectrum CBD variant contains almost the same phytocannabinoids as full-spectrum products, except it is THC -free.

Some individuals may prefer broad-spectrum CBD over full-spectrum as the former contains no psychoactive THC compounds.

Meanwhile, CBD isolate is the purest type of CBD on the market. Companies usually sell CBD isolate products in powdered or crystalline form.

Manufacturers obtain CBD isolate products by removing all other hemp plants ’ compounds during the extraction process to leave pure CBD .

Despite the availability of different CBD types, you must only purchase the best quality products from reputable sources. Here is some advice to consider when selecting the best CBD oil for cancer to maximize the purported health benefits of CBD.

  • Look for the CBD product ’s certificate of analysis (COA) or third-party lab results. This document confirms that the item you selected has undergone thorough lab testing.

The COA indicates that the CBD product contains the exact specifications listed on the product label to prove that it is of the highest quality.

  • Ensure that the COA confirms the absence of residual solvents, chemical additives, pesticides , heavy metals, and other harmful contaminants.
  • Confirm whether the CBD product you intend to purchase comes from organic hemp. High-quality CBD products from organic hemp ensure that the amounts of THC are within the federal limit of less than 0.3%.
  • Look up the CBD legalities within your home state and the CBD brand’s manufacturing location. Consider buying CBD oil from some reputable CBD brands that source their high potency CBD hemp from farms in Colorado , Kentucky, Oregon, and North Carolina.
  • Consult your family healthcare professional before using CBD for alleviating cancer symptoms. We recommend consulting a medical practitioner with experience in using CBD and medical cannabis products.
  • Avoid purchasing CBD products from brands that claim to sell CBD derived from hemp plants ’ stalks and seeds. Non-GMO industrial hemp stalks have very little CBD content, while its seeds have no cannabidiol .
  • Choose a CBD shop that offers a money-back guarantee for its products to ensure product satisfaction.

How Much CBD to Take for Cancer

In a Harvard Health article, Peter Grinspoon, MD, stated that the most effective therapeutic CBD dosage for cancer or any particular medical condition remains unknown ( 19 ) .

Additionally, the FDA , which regulates the safety and purity of medical drugs and dietary supplements, has not approved CBD specifically for cancer.

The American Cancer Society agrees that there is a need for more longitudinal and extensive research on cannabinoids for cancer patients ( 20 ) .

The organization supports the need for more effective therapies that can overcome the side effects of cancer and its treatments, which are often debilitating.

Clinical trials for CBD as a single drug or adjunct cancer therapy are warranted and urgently needed.

However, authors of a 2019 study published in the Brazilian Journal of Psychiatry suggested that subjects who took 300mg of CBD experienced the most noticeable reduced stress response ( 21 ) .

According to the National Cancer Institute, cancer patients may experience emotions that induce anxiety, sadness, fear, sleep problems, and confusion ( 22 ) .

Another study stated that the chronic use of CBD oil , reaching as high as 1,500mg a day, is safe for human consumption ( 23 ) . This study involved an even higher CBD dose yet recorded no harmful side effects among its participants.

Benefits of Using CBD for Cancer

A few promising studies have researched CBD’s potential in treating cancer and its side effects .

In 2012, the results of a study published in the Indian Journal of Urology suggested that cannabinoids are potential agents for managing prostate cancer ( 24 ) .

Another study published in the journal Breast Cancer Research and Treatment highlighted the efficacy of CBD in reducing breast cancer cell proliferation, invasion, and metastasis (the spread of cancer cells from where they first formed) ( 25 ) .

Later on, a 2014 study noted that Cannabis sativa extract with high cannabidiol content supports the inhibition of cancer cell proliferation and weakens colon cancer formation by activating cannabinoid receptors ( 26 ) .

Another 2014 review of related studies published in the Journal of Neuro-Oncology suggested that cannabinoids are promising compounds in the treatment of gliomas ( 27 ) . Glioma is a type of tumor that begins in the glial cells, which surround nerve cells and help them function.

Meanwhile, according to a 2016 study involving animal cancer models, cannabinoids may impede tumor cell growth ( 28 ) . This study is published in the Progress in Neuro-Psychopharmacology & Biological Psychiatry journal.

More recently, a 2019 study published in the journal Oncotarget demonstrated that CBD may initiate cell death and make glioblastoma cancer cells (brain or spinal cord cancer) more vulnerable to radiation while protecting healthy cells ( 29 ) .

In 2020, the National Cancer Institute suggested that CBD may enhance the uptake or increase the potency of certain cancer treatment drugs ( 30 ) .

Risks of Using CBD for Cancer

Although existing studies highlight CBD’s promising results, there is minimal evidence that supports claims highlighting CBD as a viable treatment for any cancer .

The World Health Organization (WHO) says that CBD is “generally well-tolerated with a good safety profile ( 31 ) .” Still, the FDA prohibits the marketing of CBD oil as dietary supplements or medicine for any condition ( 32 ) .

The FDA ensures the safety of human and animal drugs to protect public health ( 33 ) . The agency has approved Epidiolex only as a CBD treatment for children with seizures associated with rare forms of epilepsy : Dravet syndrome and Lennox-Gastaut syndrome.

With significant scientific evidence, Epidiolex is the first and only FDA -approved medication derived from marijuana plants ( 34 ) .

Meanwhile, the FDA has also approved two drugs, dronabinol and nabilone, as synthetic forms of THC for treating chemotherapy-related nausea ( 35 ) .

However, note that using CBD may induce side effects , including dry mouth, drowsiness, diarrhea, reduced appetite, and fatigue ( 36 ) .

CBD also has the risk of interacting with certain medications or supplements that you may already be taking ( 37 ) . Similarly, a 2017 research suggested that CBD may interact with other drugs and alter how the body metabolizes certain medications ( 38 ) .

Legality of CBD

In the USA, you can use CBD legally on a federal level. This legality only applies to 47 out of the 50 states, each with varying degrees of regulation for CBD use ( 39 ) . You may only travel with CBD between states that share similar CBD restrictions.

CBD’s legality in the US was made possible with the Agriculture Improvement Act of 2018 or the 2018 Farm Bill ( 40 ) . This law redefined hemp as cannabis plants with less than 0.3% THC on a dry weight basis to differentiate hemp plants from marijuana plants.

H emp plants and marijuana plants are both varieties of Cannabis sativa plants. Marijuana plants are cannabis plants with more than the established 0.3% THC limit.

Cannabis plants ’ components include terpenes , fatty acids, flavonoids, and cannabinoids . CBD and THC are present in both hemp and marijuana plants because they are the most abundant cannabinoids in cannabis plants .

The psychoactive effects of THC make people experience getting high. This euphoric effect is a critical factor in the legality of CBD products .

CBD oil with the federally legal limit of 0.3% THC by dry weight does not produce euphoria, yet you can still benefit from cannabis plants ’ purported benefits.

Historically, all varieties of cannabis were Schedule I drugs, according to the 1970 Federal Controlled Substances Act ( 41 ) . Schedule I drugs consist of potentially abusive or addictive substances without any officially recognized health benefits.

When c ongress approved the 2018 Farm Bill, hemp plants were removed from the Schedule I category.

The 2018 Farm Bill also gave the FDA the authority to regulate CBD’s circulation on the market ( 42 ) . The agency reprimands CBD companies that make unproven claims of CBD’s health benefits to sell CBD products .

The 2018 Farm Bill relaxed the legal restrictions of producing, manufacturing, and owning hemp-derived CBD products . Still, state laws are the primary authority in drug-related offenses, meaning local laws may supersede federal law ( 43 ) .

Product Frequently
Asked Questions

Cannabidiol has the potential to prevent cancer-related nausea and vomiting from a wide range of causes, including chemotherapy for cancer treatment ( 44 ) .

The journal Progress in Neuro-Psychopharmacology & Biological Psychiatry published a 2016 study suggesting that cannabinoids have antitumor effects and impede tumor growth ( 45 ) .

Another study noted a promising relationship between cannabis and bladder cancer ( 46 ) .

Note that these studies only mention cannabinoids in relation to cancer treatment. While CBD is a cannabinoid in cannabis plants, more longitudinal research linking CBD to cancer treatment is necessary.

CBD has a good safety profile, according to the World Health Organization ( 47 ) . There is no link between CBD and worsening cancer.

However, drug interactions remain a possibility with CBD products and other medications you may be taking for cancer ( 48 ) .

Based on a 2020 review, the National Cancer Institute suggest ed that CBD may enhance the uptake or boost the potency of certain drugs used for cancer treatment ( 49 ) .

CBD is not a substitute for cancer therapy . However, you may use CBD as a complementary or alternative treatment to reduce symptoms of cancer on top of the cancer treatments you may already be taking.

The journal Oncotarget published a study in 2019 that demonstrated CBD’s ability to make glioblastoma cancer cells more sensitive to radiation and initiate cell death while protecting healthy cells ( 50 ) .

Cannabidiol does not show up on a drug test, unlike THC .

However, the best CBD products for cancer contain THC within the 0.3% limit. The volume of THC you consume may accumulate with frequent use.

You must proceed with caution when taking CBD products with THC , especially when there is a scheduled drug test, because accumulated amounts may be detectable on a drug test ( 51 ) .

High-quality CBD for cancer should include THC within the federally legal limit of 0.3% by dry weight. The presence of THC, other cannabinoids, and phytocompounds ensures that the CBD product produces the entourage effect.

If you intend to take CBD oil for cancer, consider buying products from the brands we have collected here, which are available in dispensaries and their online stores .

There is no standard dosing for how much CBD you should take for cancer because the FDA has not approved CBD for cancer treatment .

Still, a study suggested that the chronic use of CBD oil , reaching as high as 1,500 mg a day, is safe for humans (52) .